Results 121 to 130 of about 22,252 (260)

[Echinocandins].

Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia, 2012
The echinocandins, caspofugin, micafungin, and anidulafungin, are lipopeptides that inhibit fungal growth by binding to β - (1.3) d glucan synthase. This enzyme is responsible for the formation of the peptidoglycan cell wall, and it is essential in fungi such as Candida spp, but less important in the case of Aspergillus and Fusarium species.
Jorge A, Cortés L, July A, Russi N
openaire   +1 more source

Coagulation dysfunction events associated with echinocandins: a real-world study from FDA adverse event reporting system (FAERS) database

Thrombosis Journal
Background Echinocandins belong to the fourth generation of antifungals, and there are no systematic studies on their risk in coagulation dysfunction; this study will predict the risk of coagulation dysfunction of echinocandins using the US Food and Drug
Qian Cheng, Ye Wu, Zeyu Yao, Mengling Ouyang, Shupeng Zou, Xuan Shi, Yazheng Zhao, Minghui Sun   +7 more
doaj   +1 more source

Review of the guidelines for the treatment and prevention of invasive candidiasis in newborns and children [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
nvasive infections caused by Candida species are the most common invasive fungal infections in children of different age groups. Premature neonates, especially newborns with low and extremely low birth-weight, have very high mortality rates, with the ...
Veselov A.V.
doaj  

Antifungal Drugs

Metabolites, 2020
We reviewed the licensed antifungal drugs and summarized their mechanisms of action, pharmacological profiles, and susceptibility to specific fungi. Approved antimycotics inhibit 1,3-β-d-glucan synthase, lanosterol 14-α-demethylase, protein ...
Jiří Houšť, Jaroslav Spížek, Vladimír Havlíček   +2 more
doaj   +1 more source

Micafungin versus anidulafungin in critically ill patients with invasive candidiasis: A retrospective study [PDF]

, 2016
_Background:_ In critically ill patients the incidence of invasive fungal infections caused by Candida spp. has increased remarkably. Echinocandins are recommended as initial treatment for invasive fungal infections. The safety and efficacy of micafungin
Geest, P.J. (Patrick) van der, Groeneveld, A.B.J. (Johan), Hunfeld, N.G.M. (Nicole), Ladage, S.E. (Sophie E.)   +3 more
core   +3 more sources

In Vitro Interactions of Echinocandins with Triazoles Against Multidrug-Resistant Candida auris

Antimicrobial Agents and Chemotherapy, 2017
We determined the in vitro interactions between echinocandins and azoles against 10 multidrug-resistant Candida auris strains by use of a microdilution checkerboard technique.
H. Fakhim, A. Chowdhary, A. Prakash, A. Vaezi, E. Dannaoui, J. Meis, H. Badali   +6 more
semanticscholar   +1 more source

Isolation, RP‐UHPLC‐ESI‐LIT‐Orbitrap‐MS/MS‐Based Metabolic Profiling and Anticandidal Activity of the Root and Leaf Secondary Metabolites of Monotes Kerstingii Gilg (Dipterocarpaceae)

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
This paper describes the isolation and antifungal activity of secondary metabolites from the leaves and roots of Monotes kerstingii. The distribution of these metabolites in the roots and leaves was achieved through comprehensive RP‐UHPLC‐Orbitrap‐MS and MS/MS analysis.
Sorelle Kache Fotsing, Dominique Ngnintedo, Yanick Kevin Dongmo Melogmo, Alena Soboleva, Kevine Dongmo Jumeta, Bruno Ndjakou Lenta, Fabrice Fekam Boyom, Andrej Frolov, Norbert Arnold, Ludger A. Wessjohann, Norbert Sewald, Bonaventure Tchaleu Ngadjui, Ghislain Wabo Fotso   +12 more
wiley   +1 more source

Surveillance of Candida spp Bloodstream Infections: Epidemiological Trends and Risk Factors of Death in Two Mexican Tertiary Care Hospitals [PDF]

, 2014
Introduction: Larger populations at risk, broader use of antibiotics and longer hospital stays have impacted on the incidence of Candida sp. bloodstream infections (CBSI).Objective: To determine clinical and epidemiologic characteristics of patients with
Alvarado Matute, Tito, Colombo, Arnaldo L., Cornejo Juárez, Patricia, Cortés, Jorge, Corzo León, Dora E., Echevarría, Juan I., Guzmán Blanco, Manuel, Macías, Alejandro E., Nucci, Marcio, Ostrosky Zeichner, Luis, Ponce de León, Alfredo, Ponce de León, Alfredo, Queiroz Telles, Flavio, Santolaya de Pablo, María Elena, Sifuentes Osornio, José, Thompson Moya, Luis, Tiraboschi, Iris Nora, Zurita, Jeannete   +17 more
core   +5 more sources

The problem of systemic candidosis after transplantation of solid organs. Review of the literature

Трансплантология (Москва), 2018
The article presents current views on the epidemiology, diagnosis and treatment of candidosis with organ transplantation.
S. V. Zhuravel, A. O. Chugunov, T. V. Chernenkaya   +2 more
doaj   +1 more source

Candida auris Bloodstream Infections in Russia

Antibiotics, 2020
Candida auris—a fungus (yeast) that can cause hospital outbreaks was first recognized in 2009. The authors report data on 38 cases of C. auris bloodstream infections in multidisciplinary hospitals situated in two distantly located regions of Russia ...
Natalia E. Barantsevich, Antonina V. Vetokhina, Natalia I. Ayushinova, Olga E. Orlova, Elena P. Barantsevich   +4 more
doaj   +1 more source