Results 101 to 110 of about 22,252 (260)
Echinocandin Resistance in Candida [PDF]
Clinical Infectious Diseases, 2015 Invasive fungal infections are an important infection concern for patients with underlying immunosuppression. Antifungal therapy is a critical component of patient care, but therapeutic choices are limited due to few drug classes. Antifungal resistance, especially among Candida species, aggravates the problem.
openaire +2 more sources
A Review of Antifungals and their Mono- and Combination- therapy in the Treatment of Invasive Fungal Infections [PDF]
Journal of Kerman University of Medical Sciences, 2016 Invasive fungal infections with high mortality rate are a growing health concern in hospitals and medical centers. The infection usually occurs in people with compromised immune systems.
Amir Arastefar, Parisa Badiee
doaj
Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis. [PDF]
, 2020 There are limited treatment options for immunosuppressed patients with lethal invasive fungal infections due to Fusarium and Scedosporium Manogepix (MGX; APX001A) is a novel antifungal that targets the conserved Gwt1 enzyme required for localization of ...
Alkhazraji, Sondus +8 more
core +1 more source
Candida parapsilosis associated with cervical necrotizing fasciitis and descending mediastinitis [PDF]
, 2017 published_or_final_versio
Chan, YW, Choi, WK, Lee, CC
core +1 more source
Environmental Microbiology, 2020 The antifungal echinocandin lipopeptide, acrophiarin, was circumscribed in a patent in 1979. We confirmed that the producing strain NRRL 8095 is Penicillium arenicola and other strains of P.
N. Lan +7 more
semanticscholar +1 more source
Invasive Fungal Infections After Intestine Transplantation: Epidemiology and Outcomes
Mycoses, Volume 69, Issue 5, May 2026.ABSTRACT Background Invasive fungal infections (IFIs) represent a major complication after intestine transplantation, with reported incidence rates between 40% and 49%. These infections are associated with high morbidity and allograft loss. This study evaluates the impact of post‐transplant IFIs on graft outcomes in intestine transplant recipients ...
Mayyadah H. Alabdely +4 more
wiley +1 more source
Comparison of echinocandin antifungals
Therapeutics and Clinical Risk Management, 2007 The incidence of invasive fungal infections, especially those due to Aspergillus spp. and Candida spp., continues to increase. Despite advances in medical practice, the associated mortality from these infections continues to be substantial. The echinocandin antifungals provide clinicians with another treatment option for serious fungal infections ...
Gregory, Eschenauer +2 more
openaire +3 more sources
G3: Genes, Genomes, Genetics, 2016 Candida glabrata is an important human fungal pathogen whose incidence continues to rise. Because many clinical isolates are resistant to azole drugs, the drugs of choice to treat such infections are members of the echinocandin family, although there are
Anne G. Rosenwald +8 more
doaj +1 more source
Fungal Resistance to Echinocandins and the MDR Phenomenon in Candida glabrata
Journal of Fungi, 2018 Candida glabrata has thoroughly adapted to successfully colonize human mucosal membranes and survive in vivo pressures. prior to and during antifungal treatment. Out of all the medically relevant Candida species, C.
K. Healey, D. Perlin
semanticscholar +1 more source
Journal of Infection and Chemotherapy, 2020 Empirical antifungal therapy is recommended in high-risk patients who have persistent febrile neutropenia (FN) despite broad-spectrum antibiotic therapy. Based on high-quality evidence, most guidelines recommend caspofungin.
Chizuru Yamashita +12 more
semanticscholar +1 more source