Results 101 to 110 of about 12,460 (212)

Epistasis at the cell surface: what is the role of Erg3 loss-of-function in acquired echinocandin resistance?

mBio
Echinocandins, which target the fungal β-1,3-glucan synthase (Fks), are essential for treating invasive fungal infections, yet resistance is increasingly reported.
Hans Carolus, Judith Díaz-García, Vladislav Biriukov, Stef Jacobs, Dimitrios Sofras, Alicia Pageau, Celia Lobo Romero, Lore Vinken, Pilar Escribano, Jesús Guinea, Katrien Lagrou, Christian R. Landry, Toni Gabaldón, Patrick Van Dijck   +13 more
doaj   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Current pharmacological concepts for wise use of echinocandins in the treatment of Candida infections in septic critically ill patients

, 2013
Candida infections represent challenging causes of severe sepsis and/or of septic shock in the critically ill patients. Knowledge of current pharmacological concepts may promote a more wise use of echinocandins in the management of Candida infections in ...
Pea F., Pea, Federico
core   +1 more source

Empirical and targeted therapy of candidemia with fluconazole versus echinocandins: a propensity score-derived analysis of a population-based, multicentre prospective cohort

, 2016
We compared the clinical efficacy of fluconazole and echinocandins in the treatment of candidemia in real practice. The CANDIPOP study is a prospective, population-based cohort study on candidemia carried out between May 2010 and April 2011 in 29 Spanish
Padilla, B., Lopez-Cortes, L. E., Rodriguez-Bano, J., Puig-Asensio, M., Ruiz-Camps, I., Garnacho-Montero, J., Almirante, B., Cuenca-Estrella, M.   +7 more
core   +1 more source

Species-specific and drug-specific differences in susceptibility of candida biofilms to echinocandins: Characterization of less common bloodstream isolates

, 2013
Candida species other than Candida albicans are increasingly recognized as causes of biofilm-associated infections. This is a comprehensive study that compared the in vitro activities of all three echinocandins against biofilms formed by different common
Katragkou, A., Velegraki, A., Walsh, T.J., Kyrpitzi, D., Simitsopoulou, M., Peshkova, P., Roilides, E., Tasina, E.   +7 more
core  

Antifungal Susceptibility of Candida Biofilms: Unique Efficacy of Amphotericin B Lipid Formulations and Echinocandins

, 2002
Biofilms, likely the predominant mode of device-related microbial infection, exhibit resistance to antimicrobial agents. Evidence suggests that Candida biofilms have dramatically reduced susceptibility to antifungal drugs.
D. M. Kuhn, M. A. Ghannoum, J. Chandra, T. George, P. K. Mukherjee   +4 more
core   +1 more source

The activity of echinocandins, amphotericin B and voriconazole against fluconazole-susceptible and fluconazole-resistant Brazilian Candida glabrata isolates

, 2012
The extensive use of azole antifungal agents has promoted the resistance of Candida spp to these drugs. Candida glabrata is a problematic yeast because it presents a high degree of primary or secondary resistance to fluconazole. In Brazil, C.
Milene Silva Antunes, Sydney Hartz Alves, Laura Bedin Denardi, Janio Morais Santurio, Laíssa Arévalo Bandeira, Luiz Carlos Severo, Débora Alves Nunes Mario   +6 more
core   +1 more source

Clinical Features, Outcomes, and Antifungal Susceptibility Profiles of Invasive Candida Infections in a Tertiary Care Hospital in China

Infection and Drug Resistance
Dongting Yao,1,2,* Jia Chen,3,* Guanyi Zhang3 1Department of Laboratory Medicine, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, People’s Republic of China;
Yao D, Chen J, Zhang G
doaj  

Influence of serum on in vitro susceptibility testing of echinocandins for Candida parapsilosis and Candida guilliermondii

, 2011
Echinocandins are antifungal drugs used for the treatment of invasive candidiasis and aspergillosis. They bind to serum proteins within a rate of 96 to >99%.
Gulsen Cetin-Hazirolan, Zeynep Saribas, Sevtap Arikan-Akdagli, Cetin-Hazirolan, Gulsen, Yurdakul, PINAR, Pinar Yurdakul, SARIBAŞ, ZEYNEP, Arikan-Akdagli, Sevtap   +7 more
core   +1 more source

In Vitro Activity of Rezafungin Against Planktonic and Biofilm Forms of Candida albicans and Nakaseomyces glabratus Clinical Isolates from Vascular Infections in Poland: A Pilot Study

Pharmaceutics
Background/Objectives: Certain yeast species are recognized as significant opportunistic pathogens, capable of causing severe systemic infections, particularly in immunocompromised individuals or those with disrupted physiological barriers.
Iwona Skiba-Kurek, Magdalena Namysł, Katarzyna Kania, Joanna Czekajewska, Anna Sepioło, Tomasz Gosiewski, Aldona Olechowska-Jarząb   +6 more
doaj   +1 more source