Results 81 to 90 of about 12,522 (211)

Candida glabrata Resistance to Echinocandins Associated with FKS Genes Mutations: How Urgent is the Problem? [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия, 2016
The resistance of the systemic Candida infections causative agents is a cornerstone of the selection of an effective therapy. But if before the problem was limited to resistance to azole antifungals, then by now we have enough data about cases of ...
Veselov A.V.
doaj  

Treatment of invasive candidiasis with echinocandins [PDF]

open access: yesMycoses, 2009
SummaryBlood stream infections by Candida spp. represent the majority of invasive fungal infections in intensive care patients. The high crude mortality of invasive candidiasis remained essentially unchanged during the last two decades despite new treatment options that became available.
Andreas, Glöckner   +3 more
openaire   +2 more sources

Functional Implications of Marine Biosurfactants and Their Therapeutic Potential Against Alzheimer's Disease

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
Marine‐derived biosurfactants produced by microorganisms (including bacteria, fungi, and yeast) have amphiphilic properties that facilitate membrane interactions and transport across the blood–brain barrier (BBB). These biosurfactants exhibit neuroprotective activity by targeting mechanisms implicated in Alzheimer's disease, including reducing ...
Zainab Irfan   +4 more
wiley   +1 more source

Review of the guidelines for the treatment and prevention of invasive candidiasis in newborns and children [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия, 2017
nvasive infections caused by Candida species are the most common invasive fungal infections in children of different age groups. Premature neonates, especially newborns with low and extremely low birth-weight, have very high mortality rates, with the ...
Veselov A.V.
doaj  

Decoding the Structural Complexity of Fungal α‐ and β‐Glucan Matrix via Statistical Analysis of Solid‐State NMR Chemical Shifts

open access: yesIsrael Journal of Chemistry, Volume 66, Issue 4, July 2026.
Solid‐state NMR combined with principal component analysis enables quantitative classification of fungal α‐ and β‐glucan architectures in intact cell walls, revealing conserved triple‐helical β‐1,3‐glucan conformations across species and predominantly bundled‐sheet α‐1,3‐glucan assemblies with condition‐dependent polymorphism. Statistical clustering of
Ankur Ankur   +3 more
wiley   +1 more source

Antifungal Drugs

open access: yesMetabolites, 2020
We reviewed the licensed antifungal drugs and summarized their mechanisms of action, pharmacological profiles, and susceptibility to specific fungi. Approved antimycotics inhibit 1,3-β-d-glucan synthase, lanosterol 14-α-demethylase, protein ...
Jiří Houšť   +2 more
doaj   +1 more source

[Echinocandins].

open access: yesRevista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia, 2012
The echinocandins, caspofugin, micafungin, and anidulafungin, are lipopeptides that inhibit fungal growth by binding to β - (1.3) d glucan synthase. This enzyme is responsible for the formation of the peptidoglycan cell wall, and it is essential in fungi such as Candida spp, but less important in the case of Aspergillus and Fusarium species.
Jorge A, Cortés L, July A, Russi N
openaire   +1 more source

Reduced Activity of Triazole Antifungal Agents Against Aspergillus tubingensis From a Global Collection of Genomically‐Characterized Aspergillus Section Nigri Clinical Isolates (2020–2023)

open access: yesMycoses, Volume 69, Issue 7, July 2026.
ABSTRACT Background The black moulds comprising Aspergillus section Nigri are clinically important organisms causing aspergillosis and otomycosis; triazole (azole) antifungal agents represent the primary prophylaxis and treatment option for these infections.
John H. Kimbrough   +4 more
wiley   +1 more source

The Underestimated Role of Environmental Factors in the Prevention of Invasive Fungal Disease: Experience From a European Childhood Cancer Centre

open access: yesMycoses, Volume 69, Issue 7, July 2026.
ABSTRACT Background Immunocompromised children with hematologic malignancies or undergoing allogeneic haematopoietic stem cell transplantation (HSCT) are at high risk for invasive fungal diseases (IFDs). Reported incidence varies considerably due to heterogeneous diagnostic criteria, antifungal strategies and environmental conditions.
Stefano Malvestiti   +6 more
wiley   +1 more source

The problem of systemic candidosis after transplantation of solid organs. Review of the literature

open access: yesТрансплантология (Москва), 2018
The article presents current views on the epidemiology, diagnosis and treatment of candidosis with organ transplantation.
S. V. Zhuravel   +2 more
doaj   +1 more source

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