Results 91 to 100 of about 13,317 (169)

Epistasis at the cell surface: what is the role of Erg3 loss-of-function in acquired echinocandin resistance?

mBio
Echinocandins, which target the fungal β-1,3-glucan synthase (Fks), are essential for treating invasive fungal infections, yet resistance is increasingly reported.
Hans Carolus, Judith Díaz-García, Vladislav Biriukov, Stef Jacobs, Dimitrios Sofras, Alicia Pageau, Celia Lobo Romero, Lore Vinken, Pilar Escribano, Jesús Guinea, Katrien Lagrou, Christian R. Landry, Toni Gabaldón, Patrick Van Dijck   +13 more
doaj   +1 more source

Comparative effectiveness of echinocandins and liposomal amphotericin B for fluconazole-resistant Candida parapsilosis bloodstream infections

Current therapeutic options for fluconazole-resistant Candida parapsilosis (FLZR-CP) bloodstream infections (BSI) are limited to echinocandins and liposomal amphotericin B (L-AmB).
Di Pilato, Vincenzo, Barbieri, Ramona, Tiseo, Giusy, Valerio, Maricela, Forniti, Arianna, Lupetti, Antonella, Bartalucci, Claudia, Escribano, Pilar, Salmanton-García, Jon, Vena, Antonio, Bassetti, Matteo, Limongelli, Alessandro, Mikulska, Malgorzata, Cesaretti, Mario, Muccio, Marco, Soriano Martín, Ana, Guinea, Jesus, Bouza, Emilio, Marchese, Anna, Taramasso, Lucia, Muñoz, Patricia, Giacobbe, Daniele Roberto, Falcone, Marco   +22 more
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Potential Microbiological Effects of Higher Dosing of Echinocandins [PDF]

, 2017
The antifungal "paradoxical effect” has been described as the reversal of growth inhibition at high doses of echinocandins, most usually caspofungin.
Juvvadi, Praveen R., Lamoth, Frédéric, Steinbach, William J.   +2 more
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Species-specific and drug-specific differences in susceptibility of candida biofilms to echinocandins: Characterization of less common bloodstream isolates

, 2013
Candida species other than Candida albicans are increasingly recognized as causes of biofilm-associated infections. This is a comprehensive study that compared the in vitro activities of all three echinocandins against biofilms formed by different common
Katragkou, A., Velegraki, A., Walsh, T.J., Kyrpitzi, D., Simitsopoulou, M., Peshkova, P., Roilides, E., Tasina, E.   +7 more
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Clinical Features, Outcomes, and Antifungal Susceptibility Profiles of Invasive Candida Infections in a Tertiary Care Hospital in China

Infection and Drug Resistance
Dongting Yao,1,2,* Jia Chen,3,* Guanyi Zhang3 1Department of Laboratory Medicine, The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, People’s Republic of China;
Yao D, Chen J, Zhang G
doaj  

Current pharmacological concepts for wise use of echinocandins in the treatment of Candida infections in septic critically ill patients

, 2013
Candida infections represent challenging causes of severe sepsis and/or of septic shock in the critically ill patients. Knowledge of current pharmacological concepts may promote a more wise use of echinocandins in the management of Candida infections in ...
Pea F., Pea, Federico
core   +1 more source

Empirical and targeted therapy of candidemia with fluconazole versus echinocandins: a propensity score-derived analysis of a population-based, multicentre prospective cohort

, 2016
We compared the clinical efficacy of fluconazole and echinocandins in the treatment of candidemia in real practice. The CANDIPOP study is a prospective, population-based cohort study on candidemia carried out between May 2010 and April 2011 in 29 Spanish
Padilla, B., Lopez-Cortes, L. E., Rodriguez-Bano, J., Puig-Asensio, M., Ruiz-Camps, I., Garnacho-Montero, J., Almirante, B., Cuenca-Estrella, M.   +7 more
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Antifungal Susceptibility of Candida Biofilms: Unique Efficacy of Amphotericin B Lipid Formulations and Echinocandins

, 2002
Biofilms, likely the predominant mode of device-related microbial infection, exhibit resistance to antimicrobial agents. Evidence suggests that Candida biofilms have dramatically reduced susceptibility to antifungal drugs.
D. M. Kuhn, M. A. Ghannoum, J. Chandra, T. George, P. K. Mukherjee   +4 more
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Impact of Obesity on Echinocandin Effectiveness in Treating Candida Infections: A Retrospective Observational Cohort Study

Infection and Drug Resistance
Ahmad Aljohani,1,2,* Saeed Alqahtani3,* 1Pharmaceutical Care Services, King Fahd General Hospital, Ministry of Health, Jeddah, Saudi Arabia; 2Department of Pharmacy, College of Pharmacy, Nursing and Medical Sciences, Riyadh Elm University, Riyadh,
Aljohani A, Alqahtani S
doaj  

Susceptibility profile of biofilms of non-albicans Candida spp. to echinocandins

, 2012
Charles University in Prague Faculty of Pharmacy in Hradec Kralové Department of Biological and Medical Sciences Candidate: Pavla Pešková Supervisor: Ing. Lucie Křivčíková Diploma Thesis: Susceptibility profile of biofilms of non-albicans Candida spp. to
Pešková, Pavla
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