Results 91 to 100 of about 12,522 (211)

Candida auris Bloodstream Infections in Russia

Antibiotics, 2020
Candida auris—a fungus (yeast) that can cause hospital outbreaks was first recognized in 2009. The authors report data on 38 cases of C. auris bloodstream infections in multidisciplinary hospitals situated in two distantly located regions of Russia ...
Natalia E. Barantsevich, Antonina V. Vetokhina, Natalia I. Ayushinova, Olga E. Orlova, Elena P. Barantsevich   +4 more
doaj   +1 more source

Rezafungin Versus Caspofungin in Candidaemia and Invasive Candidiasis: A Post Hoc Pooled Analysis of Phase 2 and Phase 3 Trials

Mycoses, Volume 69, Issue 7, July 2026.
ABSTRACT Background The efficacy and safety of rezafungin in invasive candidiasis (IC) and candidaemia was demonstrated in the Phase 2 STRIVE and Phase 3 ReSTORE trials, and an additional cohort of patients in ReSTORE from China (ReSTORE China). Objectives This post hoc analysis is the first time that combined data from all double‐blind, randomised ...
Alex Soriano, George R. Thompson III, Oliver A. Cornely, Matteo Bassetti, Bart Jan Kullberg, Patrick M. Honoré, Hervé Dupont, Jose A. Vazquez, Haihui Huang, Yingyuan Zhang, Sara Dickerson, Laura Cox, Peter G. Pappas   +12 more
wiley   +1 more source

Current pharmacological concepts for wise use of echinocandins in the treatment of Candida infections in septic critically ill patients [PDF]

, 2013
Candida infections represent challenging causes of severe sepsis and/or of septic shock in the critically ill patients. Knowledge of current pharmacological concepts may promote a more wise use of echinocandins in the management of Candida infections in ...
Pea F., Pea, Federico
core   +1 more source

Empirical and targeted therapy of candidemia with fluconazole versus echinocandins: a propensity score-derived analysis of a population-based, multicentre prospective cohort [PDF]

, 2016
We compared the clinical efficacy of fluconazole and echinocandins in the treatment of candidemia in real practice. The CANDIPOP study is a prospective, population-based cohort study on candidemia carried out between May 2010 and April 2011 in 29 Spanish
Padilla, B., Lopez-Cortes, L. E., Rodriguez-Bano, J., Puig-Asensio, M., Ruiz-Camps, I., Garnacho-Montero, J., Almirante, B., Cuenca-Estrella, M.   +7 more
core   +1 more source

Clinical and Laboratory Development of Echinocandin Resistance in Candida glabrata: Molecular Characterization

Frontiers in Microbiology, 2019
The pathogenic yeast Candida glabrata has become a public health issue due to the increasing number of echinocandin resistant clinical strains reported.
Olga Rivero-Menendez, Patricia Navarro-Rodriguez, Leticia Bernal-Martinez, Leticia Bernal-Martinez, Gema Martin-Cano, Laura Lopez-Perez, Isabel Sanchez-Romero, Ana Perez-Ayala, Javier Capilla, Oscar Zaragoza, Oscar Zaragoza, Ana Alastruey-Izquierdo, Ana Alastruey-Izquierdo   +12 more
doaj   +1 more source

Species-specific and drug-specific differences in susceptibility of candida biofilms to echinocandins: Characterization of less common bloodstream isolates [PDF]

, 2013
Candida species other than Candida albicans are increasingly recognized as causes of biofilm-associated infections. This is a comprehensive study that compared the in vitro activities of all three echinocandins against biofilms formed by different common
Katragkou, A., Velegraki, A., Walsh, T.J., Kyrpitzi, D., Simitsopoulou, M., Peshkova, P., Roilides, E., Tasina, E.   +7 more
core  

Antifungal Susceptibility of Candida Biofilms: Unique Efficacy of Amphotericin B Lipid Formulations and Echinocandins [PDF]

, 2002
Biofilms, likely the predominant mode of device-related microbial infection, exhibit resistance to antimicrobial agents. Evidence suggests that Candida biofilms have dramatically reduced susceptibility to antifungal drugs.
D. M. Kuhn, M. A. Ghannoum, J. Chandra, T. George, P. K. Mukherjee   +4 more
core   +1 more source

Profound cell wall remodeling in Candida parapsilosis during systemic infection confers simultaneous tolerance to echinocandins and host immunity

Microbiology Spectrum
Antifungal tolerance can promote the emergence of resistance yet often incurs fitness costs for fungal pathogens. How tolerant populations compensate for these deficits and how they may be therapeutically targeted remain poorly understood.
Farnaz Daneshnia, Liuyang Cai, Deepika Gunasekaran, Isha Gautam, Austin M. Perry, Pegah Mosharaf Ghahfarokhy, Arefeh Ebadati, Julieta Munoz, Dorian Padilla, Süleyha Hilmioglu-Polat, Shenglin Mei, Daniel J. Floyd, Miquel Àngel Schikora-Tamarit, Diego Fuentes, Maria Artigues-Lleixà, Louise A. Walker, Samuel M. Gonçalves, Mostafa Salehi, Agostinho Carvalho, Jigar V. Desai, David S. Perlin, Carol A. Munro, Alex Hopke, Tuo Wang, Toni Gabaldón, Wenjie Fang, Clarissa J. Nobile, Michael K. Mansour, Amir Arastehfar   +28 more
doaj   +1 more source

The activity of echinocandins, amphotericin B and voriconazole against fluconazole-susceptible and fluconazole-resistant Brazilian Candida glabrata isolates [PDF]

, 2012
The extensive use of azole antifungal agents has promoted the resistance of Candida spp to these drugs. Candida glabrata is a problematic yeast because it presents a high degree of primary or secondary resistance to fluconazole. In Brazil, C.
Milene Silva Antunes, Sydney Hartz Alves, Laura Bedin Denardi, Janio Morais Santurio, Laíssa Arévalo Bandeira, Luiz Carlos Severo, Débora Alves Nunes Mario   +6 more
core   +1 more source

Shifting Epidemiology and Antifungal Susceptibility Patterns of Clinical Fungal Isolates in an Intensive Care Unit (ICU) from Bucharest, Romania: A Retrospective Observational Study

Antibiotics
Background: Antifungal resistance among Candida species represents a growing clinical challenge, particularly in the context of increasing prevalence of non-albicans species. Methods: We conducted a retrospective analysis of 747 fungal isolates collected
Madalina (Preda) Solomon, Beatrice Mahler, Oana Popescu, Lia-Mara Ditu, Irina Gheorghe-Barbu, Laura Ioana Chivu, Loredana Sabina Cornelia Manolescu   +6 more
doaj   +1 more source