Results 111 to 120 of about 22,252 (260)

Integrated Genomic and Phenotypic Analyses Reveal Convergent Resistance Patterns in Clinical Candida tropicalis Isolates

open access: yesMycoses, Volume 69, Issue 5, May 2026.
ABSTRACT Background The incidence of Candida tropicalis isolation is increasing in hospital settings. High azole resistance and mortality rates make it a pathogen that requires further analysis. Methods Fourteen azole resistant Candida glabrata clinical isolates were collected from a Lebanese hospital and analysed through whole genome sequencing for ...
Christy Chedraoui   +9 more
wiley   +1 more source

Farnesol increases the activity of echinocandins against Candida auris biofilms.

open access: yesMedical Mycology, 2019
Candida auris biofilms exhibit decreased susceptibility to echinocandins, which is associated with poorer clinical outcomes. Farnesol is a quorum-sensing molecule enhancing the activity of antifungals; therefore, we evaluated the in vitro effect of ...
F. Nagy   +6 more
semanticscholar   +1 more source

Investigating the Chemical, Antifungal, and Cytotoxic Properties of Cochlospermum vitifolium Leaves and Stem Bark Extracts

open access: yesChemistry &Biodiversity, Volume 23, Issue 4, April 2026.
This figure contains images created by Freepik from Flaticon. ABSTRACT Comprehensive analysis of the chemical properties and bioactivities of plant extracts is essential for identifying compounds with therapeutic potential. This study analyzed hydroethanolic extracts from the leaves and stem bark of Cochlospermum vitifolium, investigating their ...
Francisco A. S. D. Pinheiro   +9 more
wiley   +1 more source

Resistance in Candida albicans: exploring the cell wall barrier by proteomics [PDF]

open access: yes, 2015
The incidence of candidiasis has dramatically increased and bloodstream infections due to different species of Candida are becoming a prime cause of morbidity and mortality in different types of immunocompromised patients.
Angiolella, Letizia   +2 more
core   +1 more source

Acute Invasive Pulmonary Aspergillosis With CNS Dissemination in an Immunocompetent Individual: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Invasive pulmonary aspergillosis can occur in patients without classical immunosuppression, particularly those with COPD and corticosteroid exposure. Early recognition, prompt antifungal therapy, and vigilance for neurological symptoms are essential to prevent central nervous system dissemination, which carries high mortality and significant ...
Barbare Khatiashvili   +8 more
wiley   +1 more source

Prognostic factors and historical trends in the epidemiology of candidemia in critically ill patients: an analysis of five multicenter studies sequentially conducted over a 9-year period [PDF]

open access: yes, 2014
To describe temporal trends in the epidemiology, clinical management and outcome of candidemia in intensive care unit (ICU) patients.This study was a retrospective analysis of 1,392 episodes of candidemia in 647 adult ICU patients from 22 Brazilian ...
Andreotti, Ricardo   +7 more
core   +1 more source

Visible Photosensitizing Disinfectant Spray for Combating Multidrug‐Resistant Candidozyma Auris in Healthcare Settings

open access: yesExploration, Volume 6, Issue 2, April 2026.
We designed and synthesized a dual‐type AIE photosensitizer (named TB) spray, containing a cationic quaternary ammonium unit and a glycosyl‐targeted boronic acid moiety, characterized for the elimination of biofilm infections of Candidozyma auris (C. auris) on high‐touch surfaces.
Xiaoyu Xu   +16 more
wiley   +1 more source

The Influence of COVID‐19 on the Composition and Drug Resistance of Pleural Effusion in Shandong Province

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
Our results show that the COVID‐19 pandemic has a significant impact on the detection of pathogens and drug resistance in pleural effusion in Shandong Province. ABSTRACT To analyze the composition and drug resistance changes of pleural effusion in Shandong region from 2017 to 2024, and to provide a basis for clinical empirical treatment and future ...
Wenwen Yu   +60 more
wiley   +1 more source

Candida glabrata Resistance to Echinocandins Associated with FKS Genes Mutations: How Urgent is the Problem? [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия, 2016
The resistance of the systemic Candida infections causative agents is a cornerstone of the selection of an effective therapy. But if before the problem was limited to resistance to azole antifungals, then by now we have enough data about cases of ...
Veselov A.V.
doaj  

Treatment of Aspergillosis. [PDF]

open access: yes, 2018
Infections caused by Aspergillus spp. remain associated with high morbidity and mortality. While mold-active antifungal prophylaxis has led to a decrease of occurrence of invasive aspergillosis (IA) in those patients most at risk for infection ...
Hoenigl, Martin, Jenks, Jeffrey D
core   +1 more source

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