Results 121 to 130 of about 552 (147)

Echinochrome synthesis in hybrid sea urchin embryos

Developmental Biology, 1963
Abstract These experiments were designed to assess the interaction of parental genes and maternal cytoplasm in the development of the pigment echinochrome in sea urchin embryos. Hybrids between Strongylocentrotus purpuratus and Strongylocentrotus franciscanus , including both of the reciprocal crosses, were compared with normal embryos of both ...
R R, CHAFFEE, D, MAZIA
openaire   +2 more sources

Effect of Antioxidant Echinochrome A on Bleomycin-Induced Pulmonary Fibrosis

Bulletin of Experimental Biology and Medicine, 2015
We studied the protective effect of antioxidant echinochrome A on bleomycin-induced pulmonary fibrosis in rats at the early stages of postnatal ontogeny. Administration of echinochrome A was shown to reduce the severity of bleomycin-induced oxidative stress in the lungs, prevented the development of hypertrophy of interalveolar connective tissue and ...
B Ya Ryzhavskiĭ
exaly   +3 more sources

Echinochrome Pigment Improves Male Rats' Fertility

The Natural Products Journal, 2022
Background:: Infertility is the first-rate public health problem affecting one in five married couples globally; male causes embody a significant proportion. Natural products could be an alternative or complementary inexpensive treatment for such matters. Echinochrome (Ech) is a natural quinone pigment obtained from sea urchin, and it was confirmed to
Neveen Asmet Farag, Ayman S Mohamed, Hanan Farag El Sayed, Eman Y. Salah EL Din, Abdel Rahman A. Tawfik   +4 more
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Effects of echinochrome on ventricular repolarization in acute ischemia

Journal of Electrocardiology, 2015
Myocardial ischemic electrophysiological alterations are associated with the generation of reactive oxygen species. However, electrophysiological effects of antioxidants are unclear. Our objective was to determine the effects of the antioxidant echinochrome on ventricular repolarization in a feline model of 30-min ischemia.Activation-recovery intervals
Ksenia, Sedova, Olesya, Bernikova, Jan, Azarov, Dmitry, Shmakov, Vladimir, Vityazev, Sergey, Kharin   +5 more
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Squaric Acid Ester-Based Total Synthesis of Echinochrome A

The Journal of Organic Chemistry, 2002
The total synthesis of echinochrome A is described. Both key intermediates 5 and 8 were efficiently prepared from diisopropyl squarate 7. Nucleophilic addition of aryllithium 8 to 5, followed by thermal ring-expansion/cyclization of the 1,2-adduct 4, furnished hydroquinone 3. Oxidation and full deprotection of 3 gave the title compound.
Eduardo, Peña-Cabrera, Lanny S, Liebeskind   +1 more
openaire   +2 more sources

Reaction of echinochrome trimethyl ether with aqueous ammonia

Russian Chemical Bulletin, 2010
Reaction of 7-ethyl-2,3,6-trimethoxynaphthazarin with NH3·H2O proceeds at the carbonyl groups at the C(4) atoms of the 1,4-naphthoquinonoid tautomeric forms. Methoxy group adjacent to ethyl group is the orienting substituent in this reaction.
G. I. Mel’man, V. A. Denisenko, V. Ph. Anufriev   +2 more
openaire   +1 more source

Molecular and crystal structure of the echinochrome complex with dioxane

Crystallography Reports, 2006
The molecular and crystal structures of a complex of echinochrome (2,3,5,6,8-pentahydroxy-7-ethyl-1,4-naphthoquinone) with dioxane are determined. The molecular complex 2(C12H10O7) · C4H8O2 crystallizes in the form of dark red transparent thin plates.
A. V. Gerasimenko, S. A. Fedoreyev, N. P. Mischenko   +2 more
openaire   +1 more source

7-Ethyl-2,3,5,6,8-pentahydroxy-1,4-naphthoquinone (echinochrome A): A DFT study of the antioxidant mechanism. 1. Interaction of echinochrome A with hydroperoxyl radical

Russian Chemical Bulletin, 2007
The molecular geometry and electronic structure of hydroxy-substituted naphthazarin (NZ)-7-ethyl-2,3,5,6,8-pentahydroxy-1,4-naphthoquinone (echinochrome A, (Et)NZ(β-OH)3, 1) were calculated by the B3LYP/6-311G(d) method. The influence of the (i) character of the β-OH groups dissociation and (ii) conformational mobility of molecule 1 and the anions ...
D. V. Berdyshev, V. P. Glazunov, V. L. Novikov   +2 more
openaire   +1 more source

Cytotoxic activity of intermediates and side products of echinochrome synthesis

Chemistry of Natural Compounds, 2008
The cytotoxic activity of the principal intermediates and side products of echinochrome synthesis toward gametes of the sea urchin Strogylocentrotus intermedius was studied. Di-and trichloro naphthazarin derivatives with two vicinal Cl atoms were the most active.
N. D. Pokhilo, M. I. Kiseleva, V. V. Makhan’kov, V. Ph. Anufriev   +3 more
openaire   +1 more source

Metabolic Products of Echinochrome and Its Trimethyl Ether

Chemistry of Natural Compounds
V F Anufriev
exaly   +2 more sources