Zdravniški Vestnik, 2020 Background: Ectodermal dysplasia is a rare hereditary disease, characterized by defects in the development of two to five tissues derived from the embryonic ectoderm. As a part of the manifestation, oligodontia can occur.
Sonja Zarkovic Gjurin +3 more
doaj +1 more source
Par3 interacts with Prickle3 to generate apical PCP complexes in the vertebrate neural plate
eLife, 2018 Vertebrate neural tube formation depends on the coordinated orientation of cells in the tissue known as planar cell polarity (PCP). In the Xenopus neural plate, PCP is marked by the enrichment of the conserved proteins Prickle3 and Vangl2 at anterior ...
Ilya Chuykin +2 more
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Frontiers in Physiology, 2020 Tooth agenesis is one of the most common orodental anomalies that demonstrate phenotypic and genotypic heterogeneity with a prevalence of 2.5%–7%. Mutations in WNT10A have been proposed to be the most common cause of nonsyndromic tooth agenesis (NSTA ...
Charinya Kanchanasevee +8 more
doaj +1 more source
N-cadherin acts in concert with Slit1-Robo2 signaling in regulating aggregation of placode-derived cranial sensory neurons [PDF]
, 2009 Vertebrate cranial sensory ganglia have a dual origin from the neural crest and ectodermal placodes. In the largest of these, the trigeminal ganglion, Slit1-Robo2 signaling is essential for proper ganglion assembly.
Bronner-Fraser, Marianne +1 more
core +2 more sources
A system to enrich for primitive streak-derivatives, definitive endoderm and mesoderm, from pluripotent cells in culture [PDF]
, 2012 Two lineages of endoderm develop during mammalian embryogenesis, the primitive endoderm in the pre-implantation blastocyst and the definitive endoderm at gastrulation.
Familari, M. +6 more
core +4 more sources
Transcriptional profiling of ectoderm specification to keratinocyte fate in human embryonic stem cells. [PDF]
PLoS ONE, 2015 In recent years, several studies have shed light into the processes that regulate epidermal specification and homeostasis. We previously showed that a broad-spectrum γ-secretase inhibitor DAPT promoted early keratinocyte specification in human embryonic ...
Ana Mafalda Baptista Tadeu +6 more
doaj +1 more source
A gene regulatory network underlying the formation of pre-placodal ectoderm in Xenopus laevis
BMC Biology, 2018 Background The neural plate border ectoderm gives rise to key developmental structures during embryogenesis, including the neural crest and the preplacodal ectoderm.
Santosh Kumar Maharana +1 more
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Role of Smad4 from ocular surface ectoderm in retinal vasculature development [PDF]
International Journal of Ophthalmology, 2020 "AIM: To investigate how signals from lens regulate retinal vascular development and neovascularization. METHODS: Le-Cre transgenic mouse line was employed to inactivate Smad4 in the surface ectoderm selectively.
Jing Li +3 more
doaj +1 more source
eLife, 2016 The mechanisms that underlie directional cell migration are incompletely understood. Eph receptors usually guide migrations of cells by exclusion from regions expressing Ephrin.
Oliver A Krupke +3 more
doaj +1 more source
Manipulation of cell:cell contacts and mesoderm suppressing activity direct lineage choice from pluripotent primitive ectoderm-like cells in culture. [PDF]
PLoS ONE, 2009 In the mammal, the pluripotent cells of embryo differentiate and commit to either the mesoderm/endoderm lineages or the ectoderm lineage during gastrulation.
James N Hughes +6 more
doaj +1 more source