Results 101 to 110 of about 13,941 (262)

Systemic Hormonal Contraceptive Use Is Associated With Greater Odds of Rotator Cuff Tears, Shoulder Instability, Dislocation, and Other Shoulder Pathologies: A Propensity Matched Epidemiological Study

Arthroscopy, EarlyView.
Purpose To evaluate whether systemic estrogen‐only, progestin‐only, or combined hormonal contraceptives (HCs) are associated with increased risk of shoulder pathologies in reproductive‐age females. Methods A retrospective cohort study of female patients presenting to clinic from 2013 to 2020 and aged 13‐50 with 5 years of follow‐up was conducted using ...
Argen Omurzakov, Arsen M. Omurzakov, Robert J. Burkhart, Aakash K. Shah, Rayyan Abid, James E. Voos, Jacob G. Calcei, John M. Apostolakos   +7 more
wiley   +1 more source

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

Animal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar, Muhammad Arslan Asif, Layla Al‐Mitib, Nabeela Ashiq, Haojie Wang, Yalei Cui, Boshuai Liu, Shucheng Huang, Yinghua Shi   +8 more
wiley   +1 more source

Early pharmacological blockade of the CXCL12-CXCR4 axis attenuates vertebral hypercalcification in a zebrafish model of pseudoxanthoma elasticum

Biochemistry and Biophysics Reports
Pseudoxanthoma elasticum (PXE), caused by pathogenic variants in ABCC6, is characterized by pathological ectopic calcification with poorly understood mechanisms and no effective therapies.
Jianjian Sun, Jichang Huang, Renjie Zhang, Shubin Zhang, Tao P. Zhong, Ping Zhu   +5 more
doaj   +1 more source

Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum [PDF]

, 2011
Pseudoxanthoma elasticum (PXE) is an autosomal recessive disorder in which calcification of connective tissue leads to pathology in skin, eye and blood vessels. PXE is caused by mutations in ABCC6.
Gorgels, TGMF (Theo), Ivandic, Boris, Ivandic, B. (Boris), Waarsing, J.H. (Jan), Schlingemann, Reinier O., Vermeer, C, Herfs, M, Versteeg, D, Bergen, Arthur, Bergen, A.A.B., Schoensiegel, F, Sato, T, Cees Vermeer, Schlingemann, RO, Schoensiegel, Frank, Marjolein Herfs, Ivandic, B, Gorgels, T.G.M.F. (Theo), Schoensiegel, F. (Frank), Schlingemann, R.O. (Reinier), Schurgers, LJ, Versteeg, D. (Daniëlle), Arthur A. B. Bergen, Schurgers, Leon J.; id_orcid, Bergen, Arthur A B, Waarsing, J.H., Schurgers, L.J. (Leon), Schlingemann, R.O., Gorgels, Theo G. M. F., Theo G. M. F. Gorgels, Jan H. Waarsing, Vermeer, C., Sato, T. (Toshiro), Bergen, A.A.B. (Arthur), Schurgers, Leon J., Daniëlle Versteeg, Ivandic, B., Frank Schoensiegel, Boris Ivandic, Schoensiegel, F., Schurgers, L.J., Versteeg, D., Herfs, Marjolein, Sato, T., Waarsing, Jan H., Bergen, Arthur A. B., Sato, Toshiro, Vermeer, Cees, Waarsing, Jan, Gorgels, T.G.M.F., Herfs, M., Toshiro Sato, Herfs, M. (Marjolein), Vermeer, C. (Cees), Reinier O. Schlingemann, Versteeg, Danielle, Leon J. Schurgers   +56 more
core   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Recent Advances in Research on Human Aortic Valve Calcification

Journal of Pharmacological Sciences, 2014
Aortic valve calcification can aggravate aortic stenoses, and it is a significant cause of sudden cardiac death. The increasing number of patients with age-related calcification is a problem in developed nations.
Ken-Ichi Furukawa
doaj   +1 more source

Increased calcification by erythrophagocytosis in aortic valvular interstitial cells

ESC Heart Failure, Volume 12, Issue 2, Page 1469-1473, April 2025.
Abstract Background Calcific aortic valve disease (CAVD) progresses over time to severe aortic stenosis and eventually heart failure. Recent evidence indicates that intraleaflet haemorrhage (ILH) strongly promotes CAVD progression. However, it remains poorly understood how it mechanistically contributes to valvular calcification.
Zihan Qin, Magnus Bäck, Anders Franco‐Cereceda, Sven‐Christian Pawelzik   +3 more
wiley   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source