Results 91 to 100 of about 4,789,885 (343)

Security of intelligent edge computing:a survey

open access: yesDianxin kexue, 2018
With the rise of edge computing,more and more attentions have been paid to security issues of edge computing.The basic concepts,system architecture and the relationship between edge computing and other computing paradigms were introduced.Then the ...
Xingshuo AN   +4 more
doaj   +2 more sources

Information-Centric Networking With Edge Computing for IoT: Research Challenges and Future Directions

open access: yesIEEE Access, 2018
Cloud computing is a paradigm that offers storage, computation, and software services on demand in the Cloud and far from end users. These services and computations are then extended to the Edge of the network with the Edge computing paradigm.
Rehmat Ullah   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Edge and Central Cloud Computing: A Perfect Pairing for High Energy Efficiency and Low-latency [PDF]

open access: yes, 2019
In this paper, we study the coexistence and synergy between edge and central cloud computing in a heterogeneous cellular network (HetNet), which contains a multi-antenna macro base station (MBS), multiple multi-antenna small base stations (SBSs) and ...
Hu, Xiaoyan   +5 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Architecture,challenges and applications of edge computing

open access: yes大数据, 2019
Edge computing is a new type of computing models that performs computing tasks at the edge of the network.Compared with cloud computing,it can respond to user’s needs more quickly and reliably.Starting from the shortcomings of cloud computing,the concept
Linzhe LI   +3 more
doaj  

Home - About - Disclaimer - Privacy