Results 91 to 100 of about 962,170 (319)
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Architecture,challenges and applications of edge computing
大数据, 2019 Edge computing is a new type of computing models that performs computing tasks at the edge of the network.Compared with cloud computing,it can respond to user’s needs more quickly and reliably.Starting from the shortcomings of cloud computing,the concept
Linzhe LI +3 more
doaj
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Development status and trend prospect of computing power infrastructure
Dianxin kexue, 2022 The development of digital technology drives the change and revolution of computing power infrastructure.The computing power infrastructure mainly referes to hardware and software infrastructure related to cloud computing, edge computing, end computing ...
Wenjuan XING, Bo LEI, Qianying ZHAO
doaj +2 more sources
Edge computing technologies for Internet of Things: a primer
Digital Communications and Networks, 2018 With the rapid development of mobile internet and Internet of Things applications, the conventional centralized cloud computing is encountering severe challenges, such as high latency, low Spectral Efficiency (SE), and non-adaptive machine type of ...
Yuan Ai, Mugen Peng, Kecheng Zhang
doaj +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
5G edge computing technology and application prospects
Dianxin kexue, 2019 Edge computing is a method of processing data physically close to where data is generated,and it is one of the key technologies of 5G.The development of network technology and the demand of business applications have jointly promoted the maturity of 5G ...
Hongyuan MA +3 more
doaj +2 more sources