Results 61 to 70 of about 962,170 (319)
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
Cloud native based edge computing: vision and challenges
物联网学报, 2021 Cloud native computing, featured by low-cost container technology, well fits edge computing.It was proposed to apply cloud native computing to make edge computing resource management and control transparent to application development and operation ...
Deze ZENG +3 more
doaj +2 more sources
An Overview on Edge Computing Research
IEEE Access, 2020 With the rapid development of the Internet of Everything (IoE), the number of smart devices connected to the Internet is increasing, resulting in large-scale data, which has caused problems such as bandwidth load, slow response speed, poor security, and ...
Keyan Cao +3 more
doaj +1 more source
Applied Sciences, 2022 With the rapid development of wireless networks, wireless edge computing networks have been widely considered. The heterogeneous characteristics of the 6G edge computing network bring new challenges to network resource scheduling.
Yaofang Li, Bin Wu
doaj +1 more source
FEBS Letters, EarlyView.The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source
Bearing thinking of edge computing based on NFV
Dianxin kexue, 2018 Aiming at introducing edge computing into operator’s network,a bearing and deployment thinking based on NFV was presented.Firstly,the industry development trends of edge computing were introduced.Then the concept,service scenarios and special ...
Yujia LUO, Liang OU, Hong TANG
doaj +2 more sources
Joint Computation Offloading and Prioritized Scheduling in Mobile Edge Computing [PDF]
, 2018 With the rapid development of smart phones, enormous amounts of data are generated and usually require intensive and real-time computation. Nevertheless, quality of service (QoS) is hardly to be met due to the tension between resourcelimited (battery ...
Gao, Lingfang
core +1 more source
FEBS Letters, EarlyView.Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki +4 more
wiley +1 more source
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
FEBS Letters, EarlyView.The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke +2 more
wiley +1 more source