Results 171 to 180 of about 3,583,329 (296)

Publishing as knowledge clubs: ASSAf Statement on the Recognition of Editors and Peer Reviewers

South African Journal of Science
Keyan G. Tomaselli
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Global consensus for the screening, diagnosis, staging, treatment, and surveillance of ovarian cancer in areas of significant resource limitations: report from the International Gynecological Cancer Society consensus meeting. [PDF]

Front Oncol
Maluf F, Helber HA, Tostes F, Maluf LA, Helito JK, Moretti-Marques R, Dal Molin GZ, Azevedo BRB, Ortiz DI, Cantu D, Silva Filho AL, Nogueira-Rodrigues A, Ribeiro R, Cintra GF, Guitmann G, de Melo AC, Paulino E, Baiocchi G, Resende L, de Almeida MS, de Andrade DA, de la Vega JL, Noll F, Fin F, Lopes A, Correa ME, Ng JS, Sanabria D, Rendon G, Heredia F, Lopes APE, Mussi MB, Bobinski M, Quintanilla MP, Meymar J, Atallah D, Tsunoda A.   +36 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

SM3DD with segmented PCA: a comprehensive method for interpreting 3D spatial transcriptomics. [PDF]

NAR Genom Bioinform
Blick T, Kilgallon A, Monkman J, Cooper C, Tan CW, Killingbeck EE, Pan L, Kim Y, Liang Y, Nam A, Leon M, Guimaraes PSF, Nagashima S, Martins APC, Machado-Souza C, de Noronha L, Fraser JF, Belz GT, Souza-Fonseca-Guimaraes F, Kulasinghe A.   +19 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Clinical and laboratory markers to distinguish VEXAS from Schnitzler's syndrome: data from the AIDA network registries. [PDF]

Front Med (Lausanne)
Caggiano V, Sbalchiero J, Frassi M, Martín-Nares E, Hinojosa-Azaola A, Sikora M, Jahnz-Różyk K, Crisafulli F, Franceschini F, Airò P, Guaracha-Basañez GA, Torres-Ruiz J, Sfriso P, Bindoli S, Baggio C, Hernández-Rodríguez J, Caverzaschi VG, Espinosa G, Mayrink Giardini HA, Alves Cordeiro R, González-García A, Peña Rodríguez M, Lopalco G, Iannone F, Viapiana O, Tufan A, Kucuk H, Hissaria P, Beecher M, De Paulis A, Mormile I, Dagna L, Campochiaro C, Gidaro A, La Cava L, Bugatti S, Milanesi A, Ruiz-Irastorza G, Piga M, Conti F, Moscato P, Opris-Belinski D, Vitetta R, Chighizola C, Recke A, Tornero-Romero F, Prete M, Govoni M, Emmi G, Kawakami-Campos PA, Triggianese P, Gurnari C, Ragab G, Balistreri A, Ziȩtkiewicz M, Wiesik-Szewczyk E, Frediani B, Fabiani C, Sicuranza A, Bocchia M, Cantarini L, Vitale A.   +61 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source