Results 31 to 40 of about 3,583,329 (296)

Dzieci nędzy – from a narrative poem to a novel. A preliminary study towards a reconstruction of Stanisław Przybyszewski’s creative process

Acta Universitatis Lodziensis. Folia Litteraria Polonica, 2022
The origins of Dzieci nędzy (1913) and the story of its writing offer interesting insights into the creative work of Stanisław Przybyszewski, the most prominent writer of the Young Poland period.
Katarzyna Badowska
doaj   +1 more source

Eye-tracking as a measure of cognitive effort for post-editing of machine translation [PDF]

, 2018
The three measurements for post-editing effort as proposed by Krings (2001) have been adopted by many researchers in subsequent studies and publications.
ALPAC, Bruckner, Caffrey, Carl, Carl, Chang, Danks, Denkowski, Gaspari, Gonçalves, Hokamp, Hutchins, Hvelplund, Jakobsen, Koglin, Krings, Lacruz, Lommel, Läubli, Moorkens, Mossop, Nunes Vieira, O’Brien, O’Brien, O’Brien, Schmidtke, Senez, Shreve, Snover, Specia, Specia, Su, Teixeira, Turian, Vasconcellos, Wagner, Way, Wilms   +37 more
core   +1 more source

Neuroepigenetic Editing [PDF]

, 2018
Epigenetic regulation is intrinsic to basic neurobiological function as well as neurological disease. Regulation of chromatin-modifying enzymes in the brain is critical during both development and adulthood and in response to external stimuli. Biochemical studies are complemented by numerous next-generation sequencing (NGS) studies that quantify global
Peter J, Hamilton, Carissa J, Lim, Eric J, Nestler, Elizabeth A, Heller   +3 more
openaire   +3 more sources

Cluster Editing: Kernelization based on Edge Cuts

, 2010
Kernelization algorithms for the {\sc cluster editing} problem have been a popular topic in the recent research in parameterized computation. Thus far most kernelization algorithms for this problem are based on the concept of {\it critical cliques}.
A. Zuylen van, J. Chen, J. Dean, J. Flum, J. Gramm, J. Guo, M. Charikar, M. Tedder, M.R. Fellows, N. Ailon, N. Alon, N. Bansal, P. Berkhin, R. Niedermeier, R. Shamir, R.G. Downey, R.H. Möhring, S. Böcker, W.H. Cunningham, Z.-Z. Chen   +19 more
core   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Functional characterization of tumor-specific CRISPR-directed gene editing as a combinatorial therapy for the treatment of solid tumors

Molecular Therapy: Oncology
As we pursue clinical applications for CRISPR-directed gene editing in overcoming resistance to anticancer drugs, we have focused on genetic disruption of the transcription factor, NRF2, a master regulator of cellular stress and detoxification. The level
Kelly H. Banas, Pawel A. Bialk, Natalia Rivera-Torres, Katelynn Owens, Tori N. Reiner, Kristen M. Pisarcik, Nicole Haas, Emily Gielda, Komal Khan, Krishna Priya Narra, Eric B. Kmiec   +10 more
doaj   +1 more source

On the Threshold of Intractability [PDF]

, 2015
We study the computational complexity of the graph modification problems Threshold Editing and Chain Editing, adding and deleting as few edges as possible to transform the input into a threshold (or chain) graph.
A. Brandstädt, A. Natanzon, F.V. Fomin, J. Guo, J. Nastos, L. Cai, M. Yannakakis, M.C. Golumbic, P. Burzyn, R. Shamir, T. Feder, U. Brandes, Y. Liu, Y. Liu, Y. Liu   +14 more
core   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Endogenous leptin promotes autophagy in EBSS-induced PFCs

Animal Cells and Systems, 2019
Leptin is an important adipokine and plays a vital role in animals. However, the role of leptin in the autophagic response of pig fibroblast cells (PFCs) has not been fully elucidated.
Deling Jiao, Zhen Yang, Lulu Wang, Binyue Hu, Jing Wang, Anyong Xu, Wenmin Cheng, Baoyu Jia, Yubo Qing, Hong-Ye Zhao, Hong-Jiang Wei   +10 more
doaj   +1 more source

RAGs and Regulation of Autoantibodies [PDF]

, 2004
Autoreactive antibodies are etiologic agents in a number of autoimmune diseases. Like all other antibodies these antibodies are produced in developing B cells by V(D)J recombination in the bone marrow.
Casellas, Rafael, Jankovic, Mila, Nussenzweig, Michel C., Wardemann, ­Hedda, Yannoutsos, Nikos   +4 more
core   +1 more source