Results 91 to 100 of about 4,492,164 (288)

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

International/global networking against the backdrop of nondigital and digital editorial ventures

open access: yesZeitschrift für digitale Geisteswissenschaften, 2018
The article explores some of the continuities and discontinuities that mark the ongoing change in international editorial ventures from a nondigital to a digital framework.
João Dionísio
doaj   +1 more source

Advance Drying Technology for Heat Sensitive Products [PDF]

open access: yes, 2014
This book presents the advance drying technology for heat sensitive products cited from international journals, handbooks, and current research of authors. In the first edition, the printing and publication was funded Diponegoro University.
Djaeni, Mohamad   +2 more
core  

New advanced wireless technologies for objective monitoring of motor symptoms in parkinson's disease [PDF]

open access: yes, 2017
Edition of a Research topic of Frontiers in Neurology with 12 reviewed and accepted original papersPeer ReviewedPostprint (published ...
Cabestany Moncusí, Joan   +2 more
core   +2 more sources

Hypofractionated Radiotherapy Induces ISG15+MHC‐I+ Neutrophils to Augment Anti‐Tumor Immunity and Prime Immune Checkpoint Blockade Responses in Rectal Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu   +12 more
wiley   +1 more source

Newe landte in der historischen Sprachwissenschaft: Ein Beitrag zur Druckersprache der Nürnberger Offizin Georg Stüchs auf Grundlage der Digitaledition Paesi novamente retrovati - Newe unbekanthe landte

open access: yesZeitschrift für digitale Geisteswissenschaften, 2018
Using an examination of the orthography of a print by the printer Georg Stüchs from 1508, this paper demonstrates how modern digital editions can be used for historio-linguistic research. After an overview of the
Norbert Ankenbauer
doaj   +1 more source

Nick Havely, ed., Geoffrey Chaucer: The House of Fame [PDF]

open access: yes, 2015
This is a review of Nick Havely's edition of Geoffrey Chaucer's The House of ...
Petrina, Alessandra
core  

Xanthatin Targets CISD1 to Drive Ferroptosis and Mitophagy as a Dual Anticancer Strategy in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu   +9 more
wiley   +1 more source

Selbstzeugnisse digital – Erschließung, Präsentation und Benutzbarkeit

open access: yesZeitschrift für digitale Geisteswissenschaften, 2018
Next to the primary goal of encoding and the systematic markup of the autobiographical documents in the manuscript collection of the Herzog August Library (HAB), it is of central importance for the project ...
Inga Hanna Ralle
doaj   +1 more source

The Connection: Strategies for Creating and Operating 501(c)(3)s, 501(c)(4)s and Political Organizations - Third Edition [PDF]

open access: yes, 2012
The third edition of "The Connection" explains the different roles and functions of charities, social welfare organizations, PACs and other types of nonprofits. We clarify the federal rules and illuminate the ways these organizations can work together to
Holly Shadler
core  

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