Results 31 to 40 of about 2,091,107 (247)

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Regime de colaboração e educação em tempo integral no Brasil [PDF]

Cadernos de Pesquisa, 2017
RESUMO A ampliação da cobertura da educação em tempo integral pelas escolas públicas brasileiras consiste em uma das 20 decisões centrais do Plano Nacional de Educação 2014-2024.
Donaldo Bello de Souza, Janaína Specht da Silva Menezes, Lígia Martha C. da Costa Coelho, Elisangela da Silva Bernado   +3 more
doaj   +1 more source

Educação integral e educação de tempo integral: aproximações e distanciamentos na operacionalização do Programa Mais Educação nas escolas polos municipais rurais de Monte Negro – RO [PDF]

, 2017
Dissertação de Mestrado apresentada ao Programa de Pós-Graduação, Mestrado Acadêmico em Educação, do Núcleo de Ciências Humanas, para conclusão de curso e obtenção do título de Mestre em Educação pela Fundação Universidade Federal de Rondônia (UNIR ...
Silva, Isac Rocha da, França, Rosângela de Fátima Cavalcante   +1 more
core  

Giant Direct Magnetoelectric Effect in Nanocomposite CoFe2O4:PVDF‐TrFE Thin Films

Advanced Science, EarlyView.
A novel three‐step grow‐etch‐fill fabrication approach creates structured cobalt ferrite/ferroelectric polymer nanocomposites with high interfacial areas. Driven by efficient strain‐mediated coupling, this crystalline system achieves a giant room‐temperature magnetoelectric coefficient nearly two orders of magnitude higher than other CFO/PVDF‐TrFE thin
Muireann de h‐Óra, Lynette Keeney, Rui Miguel Gonçalves Carvalho, Aliona Nicolenco, Tuhin Maity, Jordi Sort, Luís Amorim, Pedro Martins, Judith MacManus‐Driscoll   +8 more
wiley   +1 more source

Mapping the Innovation DNA of Agribusiness Firms: A Multi‐Method Analysis of Strategic Capabilities and Performance

Agribusiness, EarlyView.
ABSTRACT Innovation is essential for competitiveness in agribusiness facing dynamic environments. This study examines how market orientation, marketing, relational, and social capabilities influence innovation performance. Using data from 751 Spanish firms and a multi‐method approach that integrates Structural Equation Modeling (PLS‐SEM), Necessary ...
Beatriz Corchuelo Martínez‐Azúa, Alvaro Dias   +1 more
wiley   +1 more source

Machine‐Learning‐Assisted Onset‐Time Determination in Transient Luminescence Thermometry

Advanced Intelligent Discovery, EarlyView.
Artificial neural networks enable autonomous extraction of onset times from transient heating curves in luminescence thermometry. Using Ln3+‐doped upconverting nanoparticles as luminescent thermometers, we combine experimental transients with physically motivated synthetic curves to enhance data diversity and improve generalization.
David J. Sousa, Erving Ximendes, Luís D. Carlos, Carlos D. S. Brites   +3 more
wiley   +1 more source

Contribuições da psicologia histórico-cultural para a coordenação pedagógica da educação integral politécnica [PDF]

, 2017
Dissertação de Mestrado apresentada ao Programa de Pós-Graduação Mestrado Acadêmico em Educação da Universidade Federal de Rondônia, como requisito para obtenção do título de Mestre em Educação.
Maciel, Antônio Carlos, Teixeira, Eliane de Araújo   +1 more
core  

Dicarboxymethyl Cellulose‐Based Mixed‐Matrix Membrane Adsorbers: Preparation, Characterization, and Protein Retention Performance

Journal of Applied Polymer Science, EarlyView.
Dicarboxymethyl cellulose is incorporated, for the first time, into a polyethersulfone membrane. The functional membranes are prepared using dimethyl isosorbide through combined non‐solvent and vapor‐induced phase separation. The resulting membranes exhibit porous structures and protein‐retention potential, highlighting the potential of this cellulose ...
Diana Gago, Giuseppe Di Luca, Francesca Russo, Ricardo Chagas, Luísa Maria Ferreira, Francesco Galiano, Isabel Coelhoso, Alberto Figoli   +7 more
wiley   +1 more source

EDUCAÇÃO INTEGRAL NO BRASIL SOB A ÓTICA DA POLÍTICA EDUCACIONAL

Ambiente, 2020
Este artigo se propõe delinear como a educação de tempo integral no Brasil encontra-se estruturada, sob a ótica das políticas públicas sobre a educação integral brasileira.
Josias Ferreira da Silva
doaj   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source