Results 61 to 70 of about 1,790,156 (306)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A Flexible Regimen of Combination Antihypertensive Therapy for Lower Blood Pressure to the Lower Target Level. Viewpoint of Cardiologist and Clinical Pharmacologist

Рациональная фармакотерапия в кардиологии, 2019
Modern tactics of antihypertensive therapy with fixed dose combination or with free combinations of antihypertensive drugs are reviewed in the article. The evidence that a flexible regimen of combination antihypertensive therapy is more reasonable in the
S. R. Gilyarevskiy, M. V. Golshmid, G. Yu. Zaharova, I. M. Kuzmina, I. I. Sinitsina   +4 more
doaj   +1 more source

Case Series of Multisystem Inflammatory Syndrome (MIS-C) in Children during the SARS-CoV-2 Pandemic in Latvia

Clinics and Practice, 2021
The total number of COVID-19 positive cases in Latvia has escalated rapidly since October 2020, peaking in late December 2020 and early January 2021.
Iveta Racko, Liene Smane, Lizete Klavina, Zanda Pucuka, Ieva Roge, Jana Pavare   +5 more
doaj   +1 more source

Partnership to Aid in Cultivating Diverse Vendors for National Grid, CVS [PDF]

, 2014
Curriculum created by Professional Education Center at the School of Continuing Studies will train diverse supply chain participants on essential skills for small business ...
Clark, Brian E.
core   +1 more source

Continuing midwifery education beyond graduation : student midwives' awareness of continuous professional development [PDF]

, 2017
Midwifery education plays an important role in educating graduates about engaging in continuous professional development (CPD) but there is a lack of empirical research analysing student midwives’ awareness of CPD beyond graduation.
Embo, Mieke, Valcke, Martin
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Probiotic Lactobacillus reuteri DSM 17938: what is known about it today?

Медицинский совет, 2019
The review is devoted to the analysis of data on the effects of Lactobacillus reuteri DSM 17938, confirmed in clinical trials. Thanks to their antimicrobial activity, L. reuteri is able to inhibit colonization by pathogenic microorganisms and restore the
I. N. Zakharova, I. V. Berezhnaya, A. Е. Kuchina, O. V. Dedikova   +3 more
doaj   +1 more source

The context, influences and challenges for undergraduate nurse clinical education: Continuing the dialogue [PDF]

, 2015
Introduction – Approaches to clinical education are highly diverse and becoming increasingly complex to sustain in complex milieu Objective – To identify the influences and challenges of providing nurse clinical education in the undergraduate setting ...
AIHW, Allan, Allan, Andrews, ANMAC, Annear, Arthur, Austria, Benner, Bernie Carter, Berragan, Bradshaw, Budgen, Buerhaus, Callaghan, Campbell, Chernomas, CIHI, Clinton, Courtney-Pratt, Cross, Daly, Debra Jackson, Dickson, Dobrowolska, Doiron, Donnelly, EU2005/36, European Commission, Fawcett, Hasson, Hayden, Holland, HWA, Jackson, Jackson, Jackson, Jan Forber, Jokelainen, Kardong-Edgren, Koch, Lauder, Mannix, Michelle DiGiacomo, Moscato, Moscato, Mulready-Shick, Myall, NHWT, Nielsen, Nishioka, NMC, NMC, O'Driscoll, Ostrogorsky, Patricia Davidson, Roxburgh, Ruth-Sahd, Salamonson, Sherman, Smith, Smith, Tanner, UKCC, Walker, Willis, Wolff   +66 more
core   +1 more source