Results 61 to 70 of about 8,255,634 (311)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

CCE connections

, 2011
Newsletter published 3 times per year by the Centre for Continuing Education at the University of Regina ...
Centre for Continuing Education
core  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Factors affecting the essential medicine prescribing behavior among general practitioners in Beijing, China: a cross-sectional study with structural equation model

BMC Primary Care
Background The aim of this study is to explore the influence of GPs’information, motivation and behavior skills on EM prescribing behavior in urban and suburban districts.
Xiaolei Chen, Zhengwen Feng, Qi Luo, Hui Li, Shuang Shao, Juan Du   +5 more
doaj   +1 more source

Probiotic Lactobacillus reuteri DSM 17938: what is known about it today?

Медицинский совет, 2019
The review is devoted to the analysis of data on the effects of Lactobacillus reuteri DSM 17938, confirmed in clinical trials. Thanks to their antimicrobial activity, L. reuteri is able to inhibit colonization by pathogenic microorganisms and restore the
I. N. Zakharova, I. V. Berezhnaya, A. Е. Kuchina, O. V. Dedikova   +3 more
doaj   +1 more source

Responsibility and Aurthority for Continuing Education and Conference Activities

, 2006
Teaching, Research, and ...
Office of Continuing Education and Conferences
core  

Thinking about Research in Continuing Education: A Meta-theoretical Primer

, 1999
Every approach to conducting research in continuing education involves background assumptions about the nature of what is being studied, the means through which one can acquire knowledge, and the purpose of the research process itself. Although often not
McLean, Scott
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Analysis of health service utilization of migrants in Beijing using Anderson health service utilization model

BMC Health Services Research, 2018
Background Migrants are the unique production of China’s urbanization process. They are often excluded from social welfare and security systems of cities, and often exposed to high health risk related closely to their health problems.
Shuang Shao, Meirong Wang, Guanghui Jin, Yali Zhao, Xiaoqin Lu, Juan Du   +5 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source