Results 61 to 70 of about 145,748 (333)

EVALUASI IMPLEMENTASI SUPERVISI MANAJERIAL DALAM MENINGKATKAN KINERJA ADMINISTRATIF DI INSTITUSI PENDIDIKAN

open access: yesJurnal Visi Ilmu Pendidikan
This research evaluates the implementation of managerial supervision to enhance administrative performance in educational institutions. The study aims to analyze how managerial supervision influences administrative efficiency and effectiveness ...
Anggi Nauli Simatupang   +3 more
doaj   +1 more source

Barriers to rational antibiotic prescription in Iran: a descriptive qualitative study

open access: yesAntimicrobial Resistance and Infection Control, 2022
Introduction Rational antibiotic prescription (RAP) refers to the purposeful and appropriate antibiotic prescription with correct dose and course to produce the most possible benefits and less possible side effects.
Ramin Sami   +4 more
doaj   +1 more source

Administration: An examination of theory and its application to secondary public schools in Cyprus with particular reference to the role of principals [PDF]

open access: yes, 1995
The purpose of this study is to present in broad lines some of the basic theories of administration and to consequently examine the way administration is exercised in the secondary public schools of Cyprus to determine whether a better understanding of ...
Constantinidou, Ellada A.
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Clinical Supervision in Nursing Education: Definitions and Models [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2013
Introduction: Clinical supervision, as a mechanism for promoting knowledge and professional skills of nurses, is a core activity in nursing practice. To use clinical supervision in nursing education, it is necessary to have a comprehensive understanding ...
khadijeh Nasiriani   +2 more
doaj  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

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