Results 91 to 100 of about 6,307,996 (298)

Comparative analysis of educational needs of patients with rheumatic diseases selected based on the Polish version of the Educational Needs Assessment Tool (Pol-ENAT)

open access: yes, 2016
Objectives: Chronic rheumatic diseases, which have a progressive course, lead to large deficits in physical, mental and social functioning. In the process of the planned and systematic education of patients/families, it is extremely important to ...
Matylda Sierakowska   +3 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Efficacy of the Social Information Processing Model in Predicting Behavioral Disorders

open access: yesCaspian Journal of Neurological Sciences, 2017
Background: The social information processing model is one of the most up-to-date cognitive models in the field of interpersonal interactions. This social-interaction-based model can be successfully used to investigate the reasons for emotional and ...
Abdolhossein Shamsi   +3 more
doaj  

Every Child Matters? An Evaluation of "Special Educational Needs" Programmes in England [PDF]

open access: yes
The need for education to help every child rather than focus on average attainment has become a more central part of the policy agenda in the US and the UK.
McNally, Sandra   +2 more
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Explanation of Self-determination Experiences in Students with Externalized Behavior Disorders: A Phenomenological Approach

open access: yesJournal of Qualitative Research in Health Sciences, 2019
Introduction: Students with externalized behavior disorders have lower levels of capacity for self-determination skills. The aim of this study was to explain self-determination experiences in students with externalized behavior disorders.
Zahra Mansurnejad   +2 more
doaj  

The Role of Family Talk on Self-Silencing, and Distress Tolerance of Mothers with Children (11-15 Years Old) with Internalized Behavioral Problems [PDF]

open access: yesمطالعات اجتماعی روان‌شناختی زنان
Given the importance of maternal health for society at large, this study aims to determine the role of Family Talk Intervention (FTI) on self-silencing and distress tolerance in mothers of children with internalized behavioral problems in Isfahan.
Sedigheh Isapareh, Amir Ghamarani
doaj   +1 more source

Authentic online learning: Aligning learner needs, pedagogy and technology [PDF]

open access: yes, 2013
Over the past few decades there has been a substantial swing among higher education practitioners towards a more constructivist approach to learning. Nevertheless, it is still evident that many instructivist models are widely used in both classroom and ...
Herrington, J., Parker, J., Maor, D.
core  

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Parent-teacher partnership: practical approaches to meet special educational needs

open access: yes, 1997
Aims to help in developing working partnerships to meet special educational needs. The book defines what it means to practice and how to achieve it, asking "How can parent-teacher partnership become a reality for all concerned and why is there resistance
Robertson, C.   +2 more
core  

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