Results 101 to 110 of about 6,307,996 (298)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

EDUCATIONAL NEEDS OF OLDER ADULTS

SOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference
The aim of the article is to find out educational needs of older adults and to discuss the process of the training course development and its implementation jointly with older learners in Lithuania. Mixed methods research was applied incorporating survey and participatory research.
Pivorienė, Jolanta, Žemaitaitytė, Irena, Bardauskienė, Raminta, Katkonienė, Agata, Sadauskas, Justinas   +4 more
openaire   +3 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Psychometric Properties of the Family Resilience Assessment Scale for Children With Disabilities in China

SAGE Open
The study aimed to explore the factor structure and psychometric properties of the Chinese version of the Family Resilience Assessment Scale for Children with Disabilities (FRAS-CWD).
Boqiong-Tian, Renhong-Shen, Rujun-Huang, Su Qiong-Xu   +3 more
doaj   +1 more source

Beyond special educational needs labeling: internalizing and externalizing symptom profiles explain school well-being in inclusive education

Frontiers in Education
IntroductionThe study investigates how students’ psychosocial problems and special educational needs (SEN) relate to their subjective school well-being (SWB) within inclusive secondary education.
Philippos Zdoupas, Désirée Laubenstein
doaj   +1 more source

The Need for Diversity in Higher Education

Academic Medicine, 2003
The author states that there is a need in all higher education, including the health professions, for racial, ethnic, and other kinds of diversity, and describes two court cases involving the University of Michigan's undergraduate and law school affirmative action admission policies. The outcomes of these cases will profoundly affect the quality of U.S.
openaire   +3 more sources

Policy Echoes: Vocational Education and Special Educational Needs

, 2013
Paper presented at the 10th JVET Conference Researching Policy and Practice in Vocational Education and Training; Worcester College, Oxford, 5 – 7 July 2013 Vocational programmes at the lowest levels have been subject to significant criticism, not least
Liz Atkins
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source