Results 81 to 90 of about 5,216,239 (335)
Rapid Fabrication of Custom Microfluidic Devices for Research and Educational Applications [PDF]
, 2019 Microfluidic devices allow for the manipulation of fluids, particles, cells, micro-sized organs or organisms in channels ranging from the nano to submillimeter scales. A rapid increase in the use of this technology in the biological sciences has prompted
Juan, Jonathan +4 more
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Actualidades Investigativas en Educación, 2014 En la actualidad, el ejercicio profesional de la docencia, en todos los niveles, requiere de competencia para hacer investigación educativa. Cumplir tal requerimiento exige el diseño de programas de formación específica, cuya implementación asegure la ...
María Margarita Villegas
doaj +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Research Impact and Sustainability in Education: A Conceptual Literature Review
Education SciencesResearch sustainability and research impact are closely related concepts, both referring to the importance of extending research projects’ outcomes, changes or benefits beyond their period of implementation.
Ricardo Torres +2 more
doaj +1 more source
Good practices, innovation or scientific research in education? A conceptual reflection [PDF]
, 2020 In this work a conceptual delimitation of "good teaching practices", "educational innovation" and "educational research" is proposed, based on both the experimental design and the quality of the evidence provided by these ...
Hernández Fernández, Antonio
core
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Highlighting research on the challenges and implications of some selected educational issues
Bahir Dar Journal of EducationThis editorial highlights the manuscripts published in the January 2024 edition of the Bahir Dar Journal of Education. Written by a total of 24 scholars from six universities and one international non-governmental organization, the manuscripts provide ...
Mulugeta Yayeh Worku
doaj +1 more source
Investigación sobre la práctica docente en las universidades
Cuaderno de Pedagogía Universitaria, 2014 La investigación sobre la práctica docente (ISPD) en el contexto universitario es un estudio crítico de la docencia que busca reflexionar sobre esta para mejorar su incidencia en la calidad del aprendizaje de los estudiantes. Este artículo se basa en la
Martha E. Báez
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source