Results 81 to 90 of about 5,216,642 (307)

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

8° Seminario Internazionale sulla Ricerca Empirica in Educazione: «Il contributo della ricerca educativa per lo sviluppo di un atteggiamento scientifico del docente»

Journal of Educational, Cultural and Psychological Studies, 2019
On 14 and 15 December 2018 at the Department of Education of the University Roma Tre has been held the 8th International Seminar on the methodology of educational research «The contribution of educational research for the development of a scientific ...
Giovanni Moretti
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Research Findings to Support Effective Educational Policies: A Guide for Policymakers [PDF]

, 2011
Updates a 2009 guide with new research on what an effective school leader does; how to improve the training of principals to meet the tough demands of their jobs; how districts can better support and evaluate principals; and how to expand learning ...

core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Interpreting Likert type, summated, unidimensional, and attitudinal scales: I neither agree nor disagree, Likert or not

Advancements in Agricultural Development
This paper provides a rationale and convention for discussing the true limits and interpretation of data collected using unidimensional, summated, Likert-type, and attitudinal scales used in research investigating human behavior, sociology, education ...
James R. Lindner, Nicholas Lindner
doaj   +1 more source

Saberes docentes e formação de professores: um breve panorama da pesquisa brasileira Teacher's knowledge and teacher's education: a panorama of Brazilian research

Educação & Sociedade, 2001
As pesquisas sobre formação e profissão docentes apontam para uma revisão da compreensão da prática pedagógica do professor, que é tomado como mobilizador de saberes profissionais.
CÉLIA MARIA FERNANDES NUNES
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Educational research fellowships [PDF]

Rheumatology, 2004
A K, Brown, S, Clarke, D A, Coady, I, Haq   +3 more
openaire   +2 more sources