Results 131 to 140 of about 3,891,523 (334)

Effect of linkage on the control of inbreeding in selection programmes

open access: yesGenetics Selection Evolution, 2000
Selection and mating methods for controlling inbreeding in selection programmes are based on relationships obtained from pedigrees. The efficiency of these methods has always been tested by studies using genetic models of independent loci. However, under
Caballero Armando   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Herbicide impacts on exotic grasses and a population of the critically endangered herb "Calystegia affinis" (Convolvulaceae) on Lord Howe Island [PDF]

open access: yes, 2013
Introduced perennial grasses are capable of altering the habitat of native species, causing reductions in population size and vigour, and potentially affecting life-history processes such as survival, pollination and seedling recruitment. We examined the
Auld, Tony D.   +5 more
core  

Decoding coalescent hidden Markov models in linear time

open access: yes, 2014
In many areas of computational biology, hidden Markov models (HMMs) have been used to model local genomic features. In particular, coalescent HMMs have been used to infer ancient population sizes, migration rates, divergence times, and other parameters ...
Harris, Kelley   +3 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Using a coalescent approach to assess gene flow and effective population size of Acrocomia aculeata (Jacq.) Lodd. Ex Mart. in the Brazilian Atlantic Forest

open access: green, 2020
Renan Marcelo Portela   +5 more
openalex   +1 more source

How many of them? Genetic diversity, survival and effective population size of the capercaillie population from the Gorce Mountains [PDF]

open access: hybrid, 2019
Sebastian Szczepański   +7 more
openalex   +1 more source

Fitting stochastic epidemic models to gene genealogies using linear noise approximation [PDF]

open access: yes, 2019
Phylodynamics is a set of population genetics tools that aim at reconstructing demographic history of a population based on molecular sequences of individuals sampled from the population of interest.
Bedford, Trevor   +3 more
core   +1 more source

Population Size and Effectiveness of Selection [PDF]

open access: yesEvolution, 1954
Everett R. Dempster, I. Michael Lerner
openaire   +1 more source

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