Results 141 to 150 of about 1,499,816 (300)

Estimate of effective population size by sibship assignment method.

open access: yes, 2020
Estimate of effective population size by sibship assignment method.
Katja Claus (5032598)   +8 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Estimates of Female Effective Population Size (NEF) and population growth.

open access: yes, 2015
CI 95%- 95% Credible interval for the estimates.1Prior bounds for population growth between-5,000 and 15,000.2Estimates for female effective population size assuming exponential population growth.3Estimates for female effective population size assuming ...
Laura V. Verrastro (693495)   +3 more
core   +1 more source

The genetic status and rescue measure for a geographically isolated population of Amur tigers

open access: yesScientific Reports
The Amur tiger is currently confronted with challenges of anthropogenic development, leading to its population becoming fragmented into two geographically isolated groups: smaller and larger ones.
Yao Ning   +12 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Estimating effective population size using close‐kin mark–recapture

open access: yesMethods in Ecology and Evolution
Close‐kin mark–recapture (CKMR) is a method that allows estimating population census size, among other parameters, through the observed number of pairs that are close‐kin including parent–offspring pairs (POPs) and half‐sibling pairs (HSPs).
Jonathan Babyn   +3 more
doaj   +1 more source

Estimating the Effective Size of European Wolf Populations

open access: yesEvolutionary Applications
ABSTRACTMolecular methods are routinely used to estimate the effective size of populations (Ne). However, underlying model assumptions are frequently violated to an unknown extent. Although simulations can detect sources of bias and help to adjust sampling strategies and analyses methods, additional information from empirical data can also be used to ...
Joachim Mergeay   +10 more
openaire   +4 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Temporal TM3 coalescent-based effective population size estimates.

open access: yes, 2016
NG = number of generations between a pair of samples. Ne = effective population size estimate. Lower and Upper 95% CI = represents a 95% Confidence Interval (CI) for Ne estimated for a pair of samples.
Tatiana Fioravanti (2609869)   +12 more
core   +1 more source

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