Results 201 to 210 of about 1,499,816 (300)

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

An empirical evaluation of effective population size estimators

, 2001
The purpose of this study was to evaluate demographic and genetic methods of estimating the effective population size of a population. Effective population size (Ne) describes how populations lose genetic variation due to random genetic drift.
Swanson, Bradley J
core  

Spatio-Temporal Changes in Effective Population Size in an Expanding Metapopulation of Eurasian Otters. [PDF]

Evol Appl
Thomas NE, Chadwick EA, Bruford MW, Hailer F.   +3 more
europepmc   +1 more source

Identity-by-descent-based estimation of the X chromosome effective population size with application to sex-specific demographic history. [PDF]

G3 (Bethesda), 2023
Cai R, Browning BL, Browning SR.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Effects of Social Structure on Effective Population Size Change Estimates. [PDF]

Evol Appl
Parreira BR, Gopalakrishnan S, Chikhi L.
europepmc   +1 more source

Drivers of strong isolation and small effective population size at a leading range edge of a widespread plant. [PDF]

Heredity (Edinb), 2023
Cisternas-Fuentes A, Koski MH.
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Effective population size of <i>Culex quinquefasciatus</i> under insecticide-based vector management and following Hurricane Harvey in Harris County, Texas. [PDF]

Front Genet, 2023
Huang X, Athrey GN, Kaufman PE, Fredregill C, Slotman MA.   +4 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source