Results 41 to 50 of about 3,832,732 (295)

Prokaryote genome fluidity is dependent on effective population size [PDF]

, 2017
Many prokaryote species are known to have fluid genomes, with different strains varying markedly in accessory gene content through the combined action of gene loss, gene gain via lateral transfer, as well as gene duplication.
A Knöppel, AO Kislyuk, B Haegeman, Elze Hesse, F Baumdicker, H Ochman, H Tettelin, HP Narra, JP Gogarten, JP Gogarten, M Lynch, M Touchon, M Vos, M Vos, MF Polz, Michiel Vos, Nadia Andrea Andreani, RW Nowell, S Wielgoss   +18 more
core   +1 more source

Application of a novel 50K SNP genotyping array to assess the genetic diversity and linkage disequilibrium in a farmed Pacific white shrimp (Litopenaeus vannamei) population

Aquaculture Reports, 2021
The inclusion of genomic information became a reality in shrimp breeding and it is expected to accelerate the genetic gain over time. The decay of linkage disequilibrium (LD) between single nucleotide polymorphisms (SNPs) is an important measure to ...
Baltasar F. Garcia, Álvaro Bonaguro, Carolina Araya, Roberto Carvalheiro, José M. Yáñez   +4 more
doaj   +1 more source

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source

Can effective population size estimates be used to monitor population trends of woodland bats? A case study of Myotis bechsteinii

Ecology and Evolution, 2021
Molecular approaches to calculate effective population size estimates (Ne) are increasingly used as an alternative to long‐term demographic monitoring of wildlife populations.
Patrick G. R. Wright, Henry Schofield, Fiona Mathews   +2 more
doaj   +1 more source

Breeding Strategies to Optimize Effective Population Size in Low Census Captive Populations: The Case of Gazella cuvieri

Animals, 2021
Small-sized animal populations can undergo significant loss of genetic variability that can lead to their extinction. Therefore, studies on animal breeding have focused on mating systems for minimizing the disappearance of genetic variability.
Candela Ojeda-Marín, Isabel Cervantes, Eulalia Moreno, Félix Goyache, Juan Pablo Gutiérrez   +4 more
doaj   +1 more source

The effect of population structure, plant size, herbivory and reproductive potential on effective population size in the temperate epiphytic orchid, Sarcochilus australis [PDF]

, 2013
Distribution of plant size and reproductive success is investigated in the temperate epiphytic orchid Sarcochilus australis (Lindl.) Rchb. f. at Kinglake National Park, Victoria, in south-eastern Australia, and applied to estimating the effective ...
Tremblay, Raymond L.
core  

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Individualized Medicine in Africa: Bringing the Practice Into the Realms of Population Heterogeneity

Frontiers in Genetics, 2022
The declared aim of “personalized”, “stratified” or “precision” approaches is to place individual variation, as ascertained through genomic and various other biomarkers, at the heart of Scientific Medicine using it to predict risk of disease or response ...
Ayman A. Hussein, Reem Hamad, Melanie J. Newport, Muntaser E. Ibrahim   +3 more
doaj   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source