Results 61 to 70 of about 1,499,816 (300)
Recent human effective population size estimated from linkage disequilibrium [PDF]
Effective population size (N(e)) determines the amount of genetic variation, genetic drift, and linkage disequilibrium (LD) in populations. Here, we present the first genome-wide estimates of human effective population size from LD data.
Tenesa, Albert +12 more
core +1 more source
Small-sized animal populations can undergo significant loss of genetic variability that can lead to their extinction. Therefore, studies on animal breeding have focused on mating systems for minimizing the disappearance of genetic variability.
Candela Ojeda-Marín +4 more
doaj +1 more source
THE EFFECTS OF POPULATION BOTTLENECKS ON CLONAL INTERFERENCE, AND THE ADAPTATION EFFECTIVE POPULATION SIZE [PDF]
Clonal interference refers to the competition that arises in asexual populations when multiple beneficial mutations segregate simultaneously. A large body of theoretical and experimental work now addresses this issue. Although much of the experimental work is performed in populations that grow exponentially between periodic population bottlenecks, the ...
Paolo R A, Campos, L M, Wahl
openaire +2 more sources
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa +8 more
wiley +1 more source
For different number of available mates, , and probability that two eggs are fertilised by the same sperm package, , we show the ratio of the effective population size () to the total population size (). Parameters: , .
Bernhard Mehlig (366454) +8 more
core +1 more source
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro +11 more
wiley +1 more source
The inclusion of genomic information became a reality in shrimp breeding and it is expected to accelerate the genetic gain over time. The decay of linkage disequilibrium (LD) between single nucleotide polymorphisms (SNPs) is an important measure to ...
Baltasar F. Garcia +4 more
doaj +1 more source
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
wiley +1 more source
Effective population size Ne by watershed, where steelhead collections are in crosshatch pattern. * indicates the NE estimate was infinity.
Erik Lesko (5101352) +6 more
core +1 more source
Molecular approaches to calculate effective population size estimates (Ne) are increasingly used as an alternative to long‐term demographic monitoring of wildlife populations.
Patrick G. R. Wright +2 more
doaj +1 more source

