Results 71 to 80 of about 1,499,816 (300)

Effective population size of current human population

Genetics Research, 2011
SummaryIn order to estimate the effective population size (Ne) of the current human population, two new approaches, which were derived from previous methods, were used in this study. One is based on the deviation from linkage equilibrium (LE) between completely unlinked loci in different chromosomes and another is based on the deviation from the Hardy ...
openaire   +2 more sources

Developments in the prediction of effective population size [PDF]

Heredity, 1994
Effective population size is a key parameter in evolutionary and quantitative genetics because it measures the rate of genetic drift and inbreeding. Predictive equations of effective size under a range of circumstances and some of their implications are reviewed in this paper.
openaire   +2 more sources

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Factors influencing effective population size in commercial populations of gilthead seabream, Sparus aurata

, 2005
Gilthead seabream (Sparus aurata) is one of the most important species among intensively reared fish in the Mediterranean region. Although there is a considerable interest in the genetic improvement of this species, many of the genetic parameters of ...
McAndrew, Brendan, Brown, R Cameron, Woolliams, John A   +2 more
core   +1 more source

Effective population size and Ne/N ratio for two populations of Northern chamois (Rupicapra rupicapra) on the edge of the species’ distribution range

BMC Ecology and Evolution
Background Effective population size (Ne) is a fundamental parameter in conservation genetics, providing relevant information on the adaptability and long-term viability of populations. In contrast, wildlife management strategies, particularly for hunted
Susanne Jacobs, Hendrik Edelhoff, Cornelia Ebert, Wibke Peters   +3 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Effective population size estimation.

, 2015
The census population size (N) versus the estimated effective population size (N̂e) for 1,000 simulated E&R experiments. For each simulation, population size was chosen uniformly at random from the interval [10, 104].
Yun S. Song (109761), Jonathan Terhorst (718564), Christian Schlötterer (13734)   +2 more
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Detecting past changes of effective population size

, 2014
Understanding and predicting population abundance is a major challenge confronting scientists. Several genetic models have been developed using microsatellite markers to estimate the present and ancestral effective population sizes.
Natacha Nikolic, Claude Chevalet, Chevalet, Claude, C., Chevalet, Claude, Nikolic, Natacha   +4 more
core   +2 more sources

Effective population sizes in cattle, sheep, horses, pigs and goats estimated from census and herdbook data

Animal, 2016
Accurate measures of effective population sizes (Ne) in livestock require good quality data and specialized skills for their computation and analysis. Ne can be estimated by Wright’s equation Ne=4MF/(M+ F) (M, F being sires and dams, respectively), but ...
S.J.G. Hall
doaj   +1 more source