Results 91 to 100 of about 111,361 (262)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Regulation and Functions of ROP GTPases in Plant–Microbe Interactions
Cells, 2020 Rho proteins of plants (ROPs) form a specific clade of Rho GTPases, which are involved in either plant immunity or susceptibility to diseases. They are intensively studied in grass host plants, in which ROPs are signaling hubs downstream of both cell ...
Stefan Engelhardt +2 more
doaj +1 more source
The Pseudomonas syringae effector protein HopZ1a suppresses effector‐triggered immunity [PDF]
New Phytologist, 2010 Featured paper: See Editorial p877
Alberto P, Macho +4 more
openaire +2 more sources
The bacterial effector HopZ1a acetylates ZIP1 kinase to suppress Arabidopsis defence responses [PDF]
, 2018 During the plant-pathogen interaction, disease or resistance are determined in the plant by a series of molecular events. The plant detects Pathogen-Associated Molecular Patterns (PAMPs), such as flagellin, triggering a defence response called PTI (PAMP ...
Beuzon-Lopez, Carmen del Rosario +4 more
core
Toward a systems understanding of plant–microbe interactions [PDF]
, 2014 Plants are closely associated with microorganisms including pathogens and mutualists that influence plant fitness. Molecular genetic approaches have uncovered a number of signaling components from both plants and microbes and their mode of actions ...
Mine, A., Sato, M., Tsuda, K.
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Crop JournalAvirulence effectors (Avrs), encoded by plant pathogens, can be recognized by plants harboring the corresponding resistance proteins, thereby initiating effector-triggered immunity (ETI).
Jiayuan Guo +10 more
doaj +1 more source
A Novel Effector Gene SCRE2 Contributes to Full Virulence of Ustilaginoidea virens to Rice
Frontiers in Microbiology, 2019 Ustilaginoidea virens, the causal agent of rice false smut (RFS), has become one of the most devastating rice pathogens worldwide. As a group of essential virulence factors, the effectors in the filamentous fungus might play central roles in the ...
Anfei Fang +10 more
doaj +1 more source
Arabidopsis TAO1 is a TIR-NB-LRR protein that contributes to disease resistance induced by the Pseudomonas syringae effector AvrB [PDF]
, 2008 The type III effector protein encoded by avirulence gene B (AvrB) is delivered into plant cells by pathogenic strains of Pseudomonas syringae. There, it localizes to the plasma membrane and triggers immunity mediated by the Arabidopsis coiled-coil (CC ...
Aarts +25 more
core +5 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source