Results 81 to 90 of about 111,361 (262)

Network properties of robust immunity in plants. [PDF]

PLoS Genetics, 2009
Two modes of plant immunity against biotrophic pathogens, Effector Triggered Immunity (ETI) and Pattern-Triggered Immunity (PTI), are triggered by recognition of pathogen effectors and Microbe-Associated Molecular Patterns (MAMPs), respectively. Although
Kenichi Tsuda, Masanao Sato, Thomas Stoddard, Jane Glazebrook, Fumiaki Katagiri   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Advances in Plant-Nematode Interactions with Emphasis on the Notorious Nematode Genus Meloidogyne. [PDF]

, 2019
Plant infections by plant-parasitic nematodes (PPNs) continue to be one of the major limitations in agricultural systems. Root-knot nematodes (RKNs), belonging to the genus Meloidogyne, are one of the most important groups of PPNs worldwide.
Kaloshian, Isgouhi, Teixeira, Marcella
core  

Modulation of plant autophagy during pathogen attack [PDF]

, 2017
In plants, the highly conserved catabolic process of autophagy has long been known as a means of maintaining cellular homeostasis and coping with abiotic stress conditions. Accumulating evidence has linked autophagy to immunity against invading pathogens,
Bozkurt, Tolga O., Duggan, Cian, Leary, Alexandre Y, Pandey, Pooja, Salguero Linares, Jose, Sanguankiattichai, Nattapong, Savage, Zachary D, Segretin, Maria Eugenia, Tumtas, Yasin, Yow, Rui Jin   +9 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

AvrBsT acetylates Arabidopsis ACIP1, a protein that associates with microtubules and is required for immunity.

PLoS Pathogens, 2014
Bacterial pathogens of plant and animals share a homologous group of virulence factors, referred to as the YopJ effector family, which are translocated by the type III secretion (T3S) system into host cells during infection.
Mi Sun Cheong, Angela Kirik, Jung-Gun Kim, Kenneth Frame, Viktor Kirik, Mary Beth Mudgett   +5 more
doaj   +1 more source

Immunity to Rice Blast Disease by Suppression of Effector-Triggered Necrosis [PDF]

Current Biology, 2016
Hemibiotrophic pathogens are some of the most destructive plant pathogens, causing huge economic losses and threatening global food security. Infection with these organisms often involves an initial biotrophic infection phase, during which the pathogen spreads in host tissue asymptomatically, followed by a necrotrophic phase, during which host-cell ...
Ruyi, Wang, Yuese, Ning, Xuetao, Shi, Feng, He, Chongyang, Zhang, Jiangbo, Fan, Nan, Jiang, Yu, Zhang, Ting, Zhang, Yajun, Hu, Maria, Bellizzi, Guo-Liang, Wang   +11 more
openaire   +2 more sources

The nuclear immune receptor RPS4 is required for RRS1SLH1-dependent constitutive defense activation in Arabidopsis thaliana [PDF]

, 2014
Plant nucleotide-binding leucine-rich repeat (NB-LRR) disease resistance (R) proteins recognize specific ‘‘avirulent’’ pathogen effectors and activate immune responses.
B Langmead, BE Howard, Bostjan Kobe, C Tasset, CF Hwang, Cécile Segonzac, D Birker, E Sinapidou, EM Kofoed, G Rallapalli, Ghanasyam Rallapalli, H Ueda, H Yang, J Hu, JD Jones, Jeffery L. Dangl, JL Dangl, Jonathan D. G. Jones, Joo Yong Woo, JR Peart, K Heidrich, K Heidrich, K Palma, K Vandepoele, Kee Hoon Sohn, KH Sohn, KH Sohn, KH Sohn, Kyung Hee Paek, L Deslandes, L Deslandes, L Deslandes, L Wirthmueller, M Bartsch, M Ikeda, M Narusaka, M Schon, M Wiermer, MD Robinson, MR Swiderski, Panagiotis F. Sarris, PN Dodds, R Breitling, R Edgar, RC Gentleman, S Bhattacharjee, S Cesari, S Xiao, SH Gabriels, Simon J. Williams, SJ Williams, SJ Williams, T Eulgem, TK Eitas, Toby E. Newman, V Bonardi, V Bonardi, W Gassmann, W Gassmann, WI Tameling, WJ Thomas, X Li, Y Noutoshi, Y Shirano, Y Zhang, Y Zhang, Y Zhang, Y Zhao, Z Zhu   +68 more
core   +3 more sources

Export of miRNAs from activated macrophages is cooperative and HuR‐dependent

FEBS Letters, EarlyView.
This study uncovers a new mechanism for miRNA export regulation in mammalian cells, driven by the RNA‐binding protein HuR. In macrophages, HuR cooperatively binds with miRNAs to export both low‐ and high‐affinity substrates, thereby influencing macrophage activation.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

A mucin-like peptide from Fasciola hepatica instructs dendritic cells with parasite specific Th1-polarizing activity [PDF]

, 2017
Fasciolosis is a trematode zoonosis of interest in public health and cattle production. We report here the immunostimulatory effect of a 66 mer mucin-like peptide from Fasciola hepatica (Fhmuc), which synergizes with lipopolysaccharide (LPS) to promote ...
Brossard, Natalie, Carmona, Carlos, Dergan Dylon, Leonardo Sebastian, Freire, Teresa, Noya, Verónica, Rabinovich, Gabriel Adrián, Rodríguez, Ernesto   +6 more
core   +1 more source