Results 11 to 20 of about 14,265 (225)

Efferocytosis in liver diseaseKey points

JHEP Reports
Summary: The process of dead cell clearance by phagocytic cells, called efferocytosis, prevents inflammatory cell necrosis and promotes resolution and repair. Defective efferocytosis contributes to the progression of numerous diseases in which cell death
Hongxue Shi, Mary P. Moore, Xiaobo Wang, Ira Tabas   +3 more
doaj   +4 more sources

Efferocytosis and Respiratory Disease

International Journal of Molecular Sciences, 2023
Cells are the smallest units that make up living organisms, which constantly undergo the processes of proliferation, differentiation, senescence and death.
Zhengjie Zhou, Xiaoping Guo, Wenxue Zheng, Yuan Yue, Guoqiang Wang, Xu Zuo, Jiaqi Zhang, Haoyu Zheng, Fang Wang, Yiming An   +9 more
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Targeting Efferocytosis in Inflammaging [PDF]

Annual Review of Pharmacology and Toxicology
Rapid removal of apoptotic cells by phagocytes, a process known as efferocytosis, is key for the maintenance of tissue homeostasis, the resolution of inflammation, and tissue repair.
KS Ravichandran (11338947), Poon, Ivan K. H., Ravichandran, Kodi S, Ivan Poon (9481238), Ravichandran, Kodi, Kodi S. Ravichandran, Ivan K.H. Poon, Poon, Ivan K H   +7 more
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Efferocytosis during Skeletal Muscle Regeneration

Cells, 2021
Efferocytosis, i.e., engulfment of dead cells by macrophages, is a crucial step during tissue repair after an injury. Efferocytosis delineates the transition from the pro-inflammatory phase of the inflammatory response to the recovery phase that ensures ...
Gaëtan Juban, Bénédicte Chazaud
doaj   +2 more sources

Efferocytosis Is an Innate Antibacterial Mechanism [PDF]

Cell Host & Microbe, 2012
SummaryMycobacterium tuberculosis persists within macrophages in an arrested phagosome and depends upon necrosis to elude immunity and disseminate. Although apoptosis of M.
Nunes-Alves, Cláudio, Booty, Matthew G., Martin, Constance J., Keren, Iris, Rosebrock, Tracy R., Desjardins, Danielle M., Remold, Heinz G., Behar, Samuel M., Fortune, Sarah M.   +8 more
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Metabolic reprogramming in efferocytosis [PDF]

Frontiers in Cell and Developmental Biology
Efferocytosis refers to the process by which phagocytes specifically identify and eliminate apoptotic cells. This process is essential for both maintaining tissue homeostasis and suppressing inflammatory responses, as well as facilitating tissue repair ...
Yingying Xi, Lei Yuan, Hui Xiao, Lu Chen, Kuo Li, Qing Yan, Aowei Wang   +6 more
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Mechanisms and Consequences of Defective Efferocytosis in Atherosclerosis

Frontiers in Cardiovascular Medicine, 2018
Efficient clearance of apoptotic cells, termed efferocytosis, critically regulates normal homeostasis whereas defective uptake of apoptotic cells results in chronic and non-resolving inflammatory diseases, such as advanced atherosclerosis.
Arif Yurdagul, Arif Yurdagul, Arif Yurdagul, Amanda C. Doran, Amanda C. Doran, Amanda C. Doran, Bishuang Cai, Bishuang Cai, Bishuang Cai, Gabrielle Fredman, Ira A. Tabas, Ira A. Tabas, Ira A. Tabas   +12 more
doaj   +2 more sources

Efferocytosis in homeostasis

Apoptotic cells are removed by professional and nonprofessional phagocytes via the process of "efferocytosis." Efferocytosis is highly efficient such that accumulation of dead cells is rarely seen in healthy tissues, even though our bodies remove 200-400
Maueröder, Christian, Ravichandran, Kodi, Gillis, Caitlin   +2 more
core   +3 more sources

Efferocytosis: A new therapeutic target for stroke

Chinese Medical Journal
. Efferocytosis refers to the process that phagocytes recognize and remove the apoptotic cells, which is essential for maintaining tissue homeostasis both in physiological and pathological conditions. Numerous studies have demonstrated that efferocytosis
Li Gao, Anatol Manaenko, Feng Zeng, Jingchen Li, Lele Liu, Ruichuan Xie, Xiaohua Zhang, John H. Zhang, Qiyong Mei, Jiping Tang, Qin Hu, Ting Gao   +11 more
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The Role of Efferocytosis in Autoimmune Diseases [PDF]

Frontiers in Immunology, 2018
Apoptosis happens continuously for millions of cells along with the active removal of apoptotic debris in order to maintain tissue homeostasis. In this respect, efferocytosis, i.e., the process of dead cell clearance, is orchestrated through cell ...
Najmeh Farahani, Sahebkar, A., Amirhossein Sahebkar, George E. Barreto, Bianconi, V., Matteo Pirro, E. Barreto, George, Farahan, Najmeh, Farahani, Najmeh, Sahebkar, Amirhossein, Seyed Mohammad Gheibi Hayat, Abdolmaleki, fereshte, Abdolmaleki, F., Vanessa Bianconi, Hayat, S. M. G., Pirro, M., Fereshte Abdolmaleki, Bianconi, Vanessa, Pirro, Matteo, Barreto, G. E., Gheibi Hayat, Seyed Mohammad   +20 more
core   +6 more sources