Results 51 to 60 of about 64,527 (310)
AntibioticsOne way that bacteria develop antibiotic resistance is by reducing intracellular antibiotic concentrations through efflux pumps. Therefore, enhancing the efficacy of antibiotics using efflux pump inhibitors provides a way to overcome this type of ...
Yena Seo, Minjun Kim, Tae-Jong Kim
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Journal of Infection in Developing Countries, 2016 Introduction: Multidrug resistance in Pseudomonas aeruginosa may be due to efflux pump overexpression. This study phenotypically examined the role of efflux pump inhibitors in decreasing antibiotic cross-resistance between beta-lactams, fluoroquinolones,
Mahshid Talebi-Taher +4 more
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The Effect of Thyme (Thymus vulgaris) Extract on the Expression of norA Efflux Pump Gene in Clinical Strains of Staphylococcus aureus [PDF]
Journal of Genetic Resources, 2018 The NorA efflux pump considered as one of the contributors to antibiotic resistance in Staphylococcus aureus strains. One of the challenges of the researchers is finding natural plant compounds with the ability to inhibit the pumps. The aim of this study
Ali Salehzadeh +3 more
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An efflux pump in genomic island GI-M202a mediates the transfer of polymyxin B resistance in Pandoraea pnomenusa M202 [PDF]
, 2023 Wenhui Gao +9 more
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Dual‐Ligand Metal‐Organic Frameworks via In Situ Amidoxime Engineering for Selective Ion Separation
Advanced Functional Materials, EarlyView.Inspired by microbial ion‐trapping mechanisms, a mild and universal strategy is developed to construct highly porous amidoxime‐functionalized MOFs. DFT calculations and molecular force measurements reveal that the dual‐ligand amidoxime configuration significantly strengthens Ga(III) affinity.
Zhifang Lv +9 more
wiley +1 more source
Efflux pumps positively contribute to rifampin resistance in rpoB mutant Mycobacterium tuberculosis
Annals of Clinical Microbiology and AntimicrobialsBackground While several recent studies have documented the importance of efflux pumps as mediators of rifampin (RIF) resistance, it remains uncertain which efflux pumps play major roles in rifampin-resistant Mycobacterium tuberculosis strains harboring ...
Fanrong Meng +16 more
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Detection of tetracyclines and efflux pump inhibitors [PDF]
Antimicrobial Agents and Chemotherapy, 1993 Screening assays for the detection of tetracyclines and inhibitors of tetracycline efflux pumps are described. The tetracycline assay is based on the observation that the tetA(B) gene encoding the efflux pump of transposon Tn10 is induced by tetracycline.
D M, Rothstein +6 more
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Triblock Polymer Engineering Enables Hydration‐Rich, High‐Performance, Fouling‐Resistant Interfaces
Advanced Functional Materials, EarlyView.A molecularly engineered triblock polymer (PHZ) rapidly reorganizes into a hydration‐rich interfacial layer on diverse surfaces, strongly suppressing hydrophobic attraction and fouling. The triblock polymer provides robust energy and steric barriers to oily foulants, enabling high‐performance antifouling at ultralow dosage.
Chenyu Qiao +6 more
wiley +1 more source
RND-type Drug Efflux Pumps from Gram-negative bacteria: Molecular Mechanism and Inhibition
Frontiers in Microbiology, 2015 Drug efflux protein complexes confer multidrug resistance on bacteria by transporting a wide spectrum of structurally diverse antibiotics. Moreover, organisms can only acquire resistance in the presence of an active efflux pump.
Henrietta eVenter +3 more
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Scientific Reports, 2023 Drug resistance is one of the most difficult challenges facing tuberculosis (TB) control. Drug efflux is among the mechanisms leading to drug resistance.
Nicoletta Campolattano +10 more
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