Results 251 to 260 of about 90,161 (342)

Lab‐Scale Continuous Biomanufacturing: A Tool for Process Development With Adaptive Strategies for Capture and Virus Inactivation

Biotechnology and Bioengineering, EarlyView.
Schematic representation of the continuous lab‐scale process. ABSTRACT Monoclonal antibodies (mAbs) are nowadays fundamental in treating a wide range of severe diseases, including cancer, infections, or autoimmune disorders. Due to their high specificity, potent activity, and fewer side effects compared to small molecular drugs, the market for mAbs is ...
Thomas Kruse, Fabian Schmitz, Janina Kilian, Jonas Austerjost, Lucas‐Nik Reger, Markus Kampmann   +5 more
wiley   +1 more source

Helicobacter pylori Efflux Pumps: A Double-Edged Sword in Antibiotic Resistance and Biofilm Formation. [PDF]

Int J Mol Sci
Krzyżek P.
europepmc   +1 more source

Isolation and Characterization of VceC Gain-of-Function Mutants That Can Function with the AcrAB Multiple-Drug-Resistant Efflux Pump of Escherichia coli

, 2006
Govindsamy Vediyappan, Tatyana Borisova, Joe A. Fralick   +2 more
openalex   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Efflux Pumps and Porins Enhance Bacterial Tolerance to Phenolic Compounds by Inhibiting Hydroxyl Radical Generation. [PDF]

Microorganisms
Sui X, Guo L, Bao Z, Xian M, Zhao G.
europepmc   +1 more source

Identification of a Novel Multidrug Efflux Pump of Mycobacterium tuberculosis

, 2008
Olga Danilchanka, Claudia Mailaender, Michael Niederweis   +2 more
openalex   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Virulence genes, efflux pumps, and molecular typing of Klebsiella pneumoniae isolates from North Iran. [PDF]

AMB Express
Birgani AH, Goli HR, Siadat SD, Fateh A, Nikbin VS, Sakhaee F, Ashrafian F, Haghshenas MR, Gholami M.   +8 more
europepmc   +1 more source

Antibacterial Efficacy of Polysaccharide Capped Silver Nanoparticles Is Not Compromised by AcrAB-TolC Efflux Pump

, 2018
Mitali Mishra, Satish Kumar, Rakesh Kumar Majhi, Luna Goswami, Chandan Goswami, Harapriya Mohapatra   +5 more
openalex   +1 more source

Shaping research in marine functional connectivity for integrated and effective marine science and management

Biological Reviews, EarlyView.
ABSTRACT Effective knowledge of ecological connectivity at sea and at the land–sea interface is key to supporting global policy goals to conserve and restore ocean biodiversity and function. However, a persistent lack of commonality in terminology and understanding around the concept of connectivity in marine ecological studies hampers its integration ...
Audrey M. Darnaude, Susanne E. Tanner, Andreu Blanco, Anna M. Sturrock, Yael Teff Seker, Angel Pérez‐Ruzafa, Jonne Kotta, Tamar Guy‐Haim, Francisco R. Barboza, Manuel Hidalgo, Katell Guizien, Jerneja Penca, Lucía López‐López, Maria Beger, Federica Costantini, Sophie Arnaud‐Haond, Cynthia Riginos, Kris Hostens, Gil Rilov, Stelios Katsanevakis, Ewan Hunter   +20 more
wiley   +1 more source