Results 81 to 90 of about 85,671 (296)

Dual‐Ligand Metal‐Organic Frameworks via In Situ Amidoxime Engineering for Selective Ion Separation

Advanced Functional Materials, EarlyView.
Inspired by microbial ion‐trapping mechanisms, a mild and universal strategy is developed to construct highly porous amidoxime‐functionalized MOFs. DFT calculations and molecular force measurements reveal that the dual‐ligand amidoxime configuration significantly strengthens Ga(III) affinity.
Zhifang Lv, Guixia Fan, Yun Bai, Guosheng Li, Peng Li, Wenjihao Hu, Yijun Cao, Wenshuai Yang, Daoguang Teng, Hongbo Zeng   +9 more
wiley   +1 more source

Role of H- and D- MATE-type transporters from multidrug resistant clinical isolates of Vibrio fluvialis in conferring fluoroquinolone resistance. [PDF]

PLoS ONE, 2012
BACKGROUND: The study seeks to understand the role of efflux pumps in multidrug resistance displayed by the clinical isolates of Vibrio fluvialis, a pathogen known to cause cholera-like diarrhoea.
Priyabrata Mohanty, Arati Patel, Ashima Kushwaha Bhardwaj   +2 more
doaj   +1 more source

RND Efflux Systems Contribute to Resistance and Virulence of Aliarcobacter butzleri

Antibiotics, 2021
Aliarcobacter butzleri is an emergent enteropathogen that can be found in a range of environments. This bacterium presents a vast repertoire of efflux pumps, such as the ones belonging to the resistance nodulation cell division family, which may be ...
Cristiana Mateus, Ana Rita Nunes, Mónica Oleastro, Fernanda Domingues, Susana Ferreira   +4 more
doaj   +1 more source

Gourd‐Inspired Design of Unit Cell with Multiple Gradients for Physiological‐Range Pressure Sensing

Advanced Functional Materials, EarlyView.
Gourd‐shaped micro‐dome arrays with coordinated modulus, conductivity, and geometric gradients co‐optimize sensitivity and linearity in piezoresistive tactile sensors. Under pressure, a solid upper dome embeds into a porous lower dome, triggering rapid contact‐area growth and series‐to‐parallel conduction, enabling unsaturated, intensity‐resolved ...
Jiayi Xu, Ming Lei, Yuanzhe Liang, Biao Qi, Ziyi Dai, Yong Zhao, Bingpu Zhou   +6 more
wiley   +1 more source

Overexpression of Efflux Pumps, Mutations in the Pumps’ Regulators, Chromosomal Mutations, and AAC(6′)-Ib-cr Are Associated With Fluoroquinolone Resistance in Diverse Sequence Types of Neonatal Septicaemic Acinetobacter baumannii: A 7-Year Single Center Study

Frontiers in Microbiology, 2021
This study investigates susceptibility toward three fluoroquinolones (ciprofloxacin, levofloxacin, moxifloxacin), multiple fluoroquinolone-resistance mechanisms, and epidemiological relationship of neonatal septicaemic Acinetobacter baumannii.
Subhasree Roy, Somdatta Chatterjee, Amrita Bhattacharjee, Pinaki Chattopadhyay, Bijan Saha, Shanta Dutta, Sulagna Basu   +6 more
doaj   +1 more source

Transcriptome assembly and profiling of Candida auris reveals novel insights into biofilm-mediated resistance [PDF]

, 2018
Candida auris has emerged as a significant global nosocomial pathogen. This is primarily due to its antifungal resistance profile but also its capacity to form adherent biofilm communities on a range of clinically important substrates.
Ben-Ami, Berkow, Berkow, Bizerra, Bongomin, Borman, Borman, Calvo, Chatterjee, Chowdhary, Defosse, Denning, Dominguez, Fisher, Fonseca, Fox, Fu, Grahl, Haas, Hager, Hashemi, Hunter, Jeffery-Smith, Kean, Kean, Kean, Kean, Kempf, Kordalewska, Kordalewska, Larkin, Liu, Liu, Lockhart, Lohse, Martínez, Mukherjee, Naglik, Naglik, Nailis, Nobile, Perfect, Pierce, Rajendran, Rajendran, Rajendran, Ramage, Ramage, Ramage, Rodrigues, Ruiz-Gaitán, Schelenz, Sherry, Sherry, Silva, Soldini, Taff, Taff, Tumbarello, Tunney, Winter, Zarnowski, Zhao, Zhao   +63 more
core   +4 more sources

Triblock Polymer Engineering Enables Hydration‐Rich, High‐Performance, Fouling‐Resistant Interfaces

Advanced Functional Materials, EarlyView.
A molecularly engineered triblock polymer (PHZ) rapidly reorganizes into a hydration‐rich interfacial layer on diverse surfaces, strongly suppressing hydrophobic attraction and fouling. The triblock polymer provides robust energy and steric barriers to oily foulants, enabling high‐performance antifouling at ultralow dosage.
Chenyu Qiao, Ziqian Zhao, Yueying Huang, Yongxiang Sun, Genglin Li, Xuguang Song, Hongbo Zeng   +6 more
wiley   +1 more source

α-Hexylcinnamaldehyde synergistically increases doxorubicin cytotoxicity towards human cancer cell lines [PDF]

, 2016
α-Hexylcinnamaldehyde (HCA), a compound derived from cinnamaldehyde, was evaluated for its potential chemosensitizing ...
DI GIACOMO, Silvia, DI SOTTO, Antonella, El Readi, Mahmoud Zaki, Mazzanti, Gabriela, Wink, Michael   +4 more
core  

Not only P-glycoprotein: amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins [PDF]

, 2017
The development of drug resistance continues to be a dominant hindrance toward curative cancer treatment. Overexpression of a wide-spectrum of ATP-dependent efflux pumps, and in particular of ABCB1 (P-glycoprotein or MDR1) is a well-known resistance ...
Assaraf, Yehuda G., Colotti, Gianni, Fazi, Francesco, Genovese, Ilaria, Ilari, Andrea   +4 more
core   +1 more source

Detection of tetracyclines and efflux pump inhibitors [PDF]

Antimicrobial Agents and Chemotherapy, 1993
Screening assays for the detection of tetracyclines and inhibitors of tetracycline efflux pumps are described. The tetracycline assay is based on the observation that the tetA(B) gene encoding the efflux pump of transposon Tn10 is induced by tetracycline.
D M, Rothstein, M, McGlynn, V, Bernan, J, McGahren, J, Zaccardi, N, Cekleniak, K P, Bertrand   +6 more
openaire   +2 more sources