Results 51 to 60 of about 2,160 (114)
Functional interplay between RND efflux pumps and GacS in Pseudomonas aeruginosa
Applied and Environmental MicrobiologyPseudomonas aeruginosa is an opportunistic human pathogen that is ubiquitous in the environment. The environmental versatility of P. aeruginosa is often attributed to a large arsenal of active efflux pumps, low permeability of the outer membrane, and ...
Justyna W. Adamiak +6 more
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Role of H- and D- MATE-type transporters from multidrug resistant clinical isolates of Vibrio fluvialis in conferring fluoroquinolone resistance. [PDF]
PLoS ONE, 2012 BACKGROUND: The study seeks to understand the role of efflux pumps in multidrug resistance displayed by the clinical isolates of Vibrio fluvialis, a pathogen known to cause cholera-like diarrhoea.
Priyabrata Mohanty +2 more
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Synthetic feedback loop model for increasing microbial biofuel production using a biosensor
Frontiers in Microbiology, 2012 Current biofuel production methods use engineered bacteria to break down cellulose and convert it to biofuel. A major challenge in microbial fuel production is that increasing biofuel yields can be limited by the toxicity of the biofuel to the organism ...
Mary eHarrison, Mary eDunlop
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How resistance-nodulation-division (RND) efflux pumps contribute to virulence.
PLoS PathogensIn Gram-negative bacteria, multi-subunit efflux pumps transport molecules across the inner membrane, periplasm, and outer membrane to the extracellular environment.
Corrella S Detweiler, Ilyas Alav
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Inhibitors of bacterial efflux pumps that also inhibit efflux pumps of cancer cells.
Anticancer research, 2012 Bacteria and cancer cells frequently increase their resistance to chemotherapeutics as a consequence of therapy. Whenever studied, refractory response to chemotherapy is due to the over-expression of efflux pumps that render the bacterium or cancer cell resistant not only to the agent used for therapy, but to many, if not all other agents as well ...
Amaral, Leonard +6 more
openaire +2 more sources
Restoration of Antibiotic Effectiveness with P. hartigii Extract Against Multidrug-Resistant E. coli
Medical Sciences ForumAntibiotic resistance poses a critical threat to global health, largely driven by bacterial efflux pumps that expel antibiotics and reduce their efficacy.
Eda Altınöz +2 more
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Effects of efflux pumps on antifungal activity of chitosan against Candida albicans
Journal of Oral MicrobiologyBackground Antifungal resistance is a major problem, commonly caused by drug-efflux pump overexpression. To evaluate if chitosan could be effective in drug-resistant Candida infections, we investigated the effects of efflux pumps on antifungal activity ...
Sureeporn Muangsawat +5 more
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Frontiers in MicrobiologyMulti-drug resistance (MDR) bacteria pose a significant global health challenge, primarily driven by the activity of multi-drug efflux pumps and their intimate coupling to bacterial membrane bioenergetics.
Ajay Pratap Singh Hada +5 more
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Microbiology SpectrumCryptococcosis is a systemic mycosis affecting immunocompromised individuals (mainly C. neoformans) and immunocompetent hosts (mainly C. gattii). Effective treatment remains challenging due to antifungal resistance, driven by efflux pumps, target enzyme ...
Gabriel Rezende Pimenta +6 more
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Iranian Journal of MicrobiologyBackground and Objectives: Pseudomonas aeruginosa (P. aeruginosa), a multidrug-resistant bacterium, represents a considerable risk in healthcare environments owing to its capacity to induce various infections. The resistance of P.
Fahad Ullah +9 more
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