Results 31 to 40 of about 170,445 (249)

Number of detected peptides from efflux pumps.

, 2023
Number of detected peptides from efflux pumps.
Holger C. Scholz (9118844), Theo M. Luider (242944), Roos H. Mars-Groenendijk (3087930), Hans C. van Leeuwen (2734018), Armand Paauw (255206), Lennard J. M. Dekker (8041340)   +5 more
core   +1 more source

Investigating functional interplay among Escherichia coli efflux pumps and their contributions to fitness [PDF]

, 2023
Bacterial efflux pumps are conserved active export proteins, many of which can provide multidrug resistance. In diderm bacteria, two efflux pump structural types — single-component efflux pumps and cell envelope-spanning multicomponent systems ...
Goetz, James
core   +1 more source

Ever-Adapting RND Efflux Pumps in Gram-Negative Multidrug-Resistant Pathogens: A Race against Time

Antibiotics, 2021
The rise in multidrug resistance (MDR) is one of the greatest threats to human health worldwide. MDR in bacterial pathogens is a major challenge in healthcare, as bacterial infections are becoming untreatable by commercially available antibiotics. One of
Martijn Zwama, Kunihiko Nishino
doaj   +1 more source

The Varied Role of Efflux Pumps of the MFS Family in the Interplay of Bacteria with Animal and Plant Cells

Microorganisms, 2019
Efflux pumps represent an important and large group of transporter proteins found in all organisms. The importance of efflux pumps resides in their ability to extrude a wide range of antibiotics, resulting in the emergence of multidrug resistance in many
Martina Pasqua, Milena Grossi, Alessandro Zennaro, Giulia Fanelli, Gioacchino Micheli, Frederic Barras, Bianca Colonna, Gianni Prosseda   +7 more
doaj   +1 more source

Antimicrobial and Efflux Pump Inhibitory Activity of Caffeoylquinic Acids from Artemisia absinthium against Gram-Positive Pathogenic Bacteria [PDF]

, 2010
Background: Traditional antibiotics are increasingly suffering from the emergence of multidrug resistance amongst pathogenic bacteria leading to a range of novel approaches to control microbial infections being investigated as potential alternative ...
Han Haley, Jacques Vervoort, Alexandre M. J. J. Bonvin, George P Tegos, Lewis Kim, Panagiotis L. Kastritis, Vervoort, J., NMR Spectroscopy, Michael R. Hamblin, Kastritis, P., Vervoort Jacques, Exarchou, Vassiliki, Vervoort, Jacques, Bonvin, A.M., Kastritis Panagiotis L., Hamblin, Michael, Tegos, George, Tegos, George P., Lewis, K., Kim Lewis, George P. Tegos, Bonvin, Alexandre M. J. J., Panagiotis L Kastritis, Bonvin Alexandre M. J. J., Sub NMR Spectroscopy, Han, H., Tegos, G.P., Alexandre M J J Bonvin, Fiamegos Yiannis C., Fiamegos, Y.C., Yiannis C Fiamegos, Kastritis, P.L., Hamblin, Michael R., Exarchou Vassiliki, Lewis, Kim, Exarchou, V., Han, Haley, Hamblin Michael R., Tegos George P., Michael R Hamblin, Fiamegos, Yiannis C., Haley Han, Yiannis C. Fiamegos, Kastritis, Panagiotis L., Vassiliki Exarchou, Bonvin, A.M.J.J., Hamblin, M.R., Vervoort, J.J.M.   +47 more
core   +2 more sources

Flavonoids as Inhibitors of Bacterial Efflux Pumps [PDF]

Molecules, 2021
Flavonoids are widely occurring secondary plant constituents, and are abundant in vegetable and fruit diets as well as herbal medicines. Therapeutic treatment options for bacterial infections are limited due to the spread of antimicrobial resistances.
Martin Waditzer, Franz Bucar
openaire   +3 more sources

Nanoparticles as Efflux Pump and Biofilm Inhibitor to Rejuvenate Bactericidal Effect of Conventional Antibiotics

Nanoscale Research Letters, 2017
The universal problem of bacterial resistance to antibiotic reflects a serious threat for physicians to control infections. Evolution in bacteria results in the development of various complex resistance mechanisms to neutralize the bactericidal effect of
Divya Gupta, Ajeet Singh, Asad U. Khan
doaj   +1 more source

Evaluation of Delafloxacin against a Burkholderia pseudomallei Efflux Mutant Panel

Microbiology Spectrum, 2022
In vitro activities of delafloxacin and ciprofloxacin were evaluated against Burkholderia pseudomallei mutants expressing or lacking defined resistance-nodulation-cell division (RND) efflux pumps using CLSI methodology at pHs of 5.8 and 7.2. Delafloxacin
Sandra P. McCurdy, Nawarat Somprasong, Herbert P. Schweizer   +2 more
doaj   +1 more source

Combination Therapy with Ciprofloxacin and Pentamidine against Multidrug-Resistant Pseudomonas aeruginosa: Assessment of In Vitro and In Vivo Efficacy and the Role of Resistance–Nodulation–Division (RND) Efflux Pumps

Antibiotics, 2023
The aim of this work was to (i) evaluate the efficacy of a combination treatment of pentamidine with ciprofloxacin against Galleria mellonella larvae infected with an MDR strain of P.
Megan Fletcher, Alex McCormack, Benjamin J. Parcell, Peter J. Coote   +3 more
doaj   +1 more source

Role of efflux pumps in reduced susceptibility to tigecycline in Acinetobacter baumannii

New Microbes and New Infections, 2019
Acinetobacter baumannii is an important human pathogen responsible for a various type of infections. These bacterial strains are generally resistant to numerous antibiotics.
S.H. Ardehali, T. Azimi, Fatemeh Fallah, M. Owrang, N. Aghamohammadi, L. Azimi   +5 more
doaj   +1 more source