Results 101 to 110 of about 3,610 (188)

Nifurtimox Is Effective Against Neural Tumor Cells and Is Synergistic with Buthionine Sulfoximine. [PDF]

open access: yes, 2016
Children with aggressive neural tumors have poor survival rates and novel therapies are needed. Previous studies have identified nifurtimox and buthionine sulfoximine (BSO) as effective agents in children with neuroblastoma and medulloblastoma.
Du, Michael   +4 more
core   +1 more source

Update on field use of the available drugs for the chemotherapy of human African trypanosomiasis [PDF]

open access: yes, 2017
Despite the fact that eflornithine was considered as the safer drug to treat human African trypanosomiasis (HAT) and has been freely available since 2001, the difficulties in logistics and cost burden associated with this drug meant that the toxic ...
DIARRA, A.   +4 more
core  

The detection and treatment of human African trypanosomiasis

open access: yesResearch and Reports in Tropical Medicine, 2012
Bernard Bouteille,1 Alain Buguet21Laboratory of Parasitology, Dupuytren University Hospital of Limoges, France; 2Polyclinic Marie-Louise Poto-Djembo, Pointe-Noire, CongoAbstract: Human African trypanosomiasis (HAT) is caused by the injection of ...
Bouteille B, Buguet A
doaj  

Monitoring the use of nifurtimox-eflornithine combination therapy (NECT) in the treatment of second stage gambiense human African trypanosomiasis

open access: yesResearch and Reports in Tropical Medicine, 2012
Jose R Franco,1 Pere P Simarro,1 Abdoulaye Diarra,2 Jose A Ruiz-Postigo,3 Mireille Samo,1 Jean G Jannin11World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland; 2World Health ...
Franco JR   +5 more
doaj  

Polyamine Metabolism for Drug Intervention in Trypanosomatids

open access: yesPathogens
Neglected tropical diseases transmitted by trypanosomatids include three major human scourges that globally affect the world’s poorest people: African trypanosomiasis or sleeping sickness, American trypanosomiasis or Chagas disease and different types of
Yolanda Pérez-Pertejo   +5 more
doaj   +1 more source

Effectiveness of a 10-Day Melarsoprol Schedule for the Treatment of Late-Stage Human African Trypanosomiasis: Confirmation from a Multinational Study (Impamel II) [PDF]

open access: yes, 2017
BackgroundTreatment of late-stage human African trypanosomiasis (HAT) with melarsoprol can be improved by shortening the regimen. A previous trial demonstrated the safety and efficacy of a 10-day treatment schedule.
Asumu, Pedro N.   +10 more
core  

Chemoprevention in hereditary digestive neoplasia: A comprehensive review. [PDF]

open access: yesTherap Adv Gastroenterol, 2023
Chevalier E, Benamouzig R.
europepmc   +1 more source

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