Results 101 to 110 of about 3,601 (193)

Nifurtimox Is Effective Against Neural Tumor Cells and Is Synergistic with Buthionine Sulfoximine. [PDF]

, 2016
Children with aggressive neural tumors have poor survival rates and novel therapies are needed. Previous studies have identified nifurtimox and buthionine sulfoximine (BSO) as effective agents in children with neuroblastoma and medulloblastoma.
Du, Michael, Scorsone, Kathleen A, Woodfield, Sarah E, Zage, Peter E, Zhang, Linna   +4 more
core   +1 more source

Antitrypanosomatid Pharmacomodulation at Position 3 of the 8-Nitroquinolin-2(1H)-one Scaffold Using Palladium-Catalysed Cross-Coupling Reactions [PDF]

, 2018
International audienceAn antikinetoplastid pharmacomodulation study at position 3 of the recently described hit molecule 3-bromo-8-nitroquinolin-2(1H)-one was conducted.
Abdoulaye, Mansour, Bonduelle, Colin, Boudot, Clotilde, Bourgeade-Delmas, Sandra, Courtioux, Bertrand, El-Kashef, Hussein, Fairlamb, Alan H., Paloque, Lucie, Pedron, Julien, Pratviel, Geneviève, Rastegari, Maryam, Sournia-Saquet, Alix, Valentin, Alexis, Verhaeghe, Pierre, Wyllie, Susan   +14 more
core   +4 more sources

Eflornithine

Indian Journal of Dermatology, Venereology and Leprology, 2007
Kruti S, Jobanputra, Aruna V, Rajpal, N G, Nagpur   +2 more
openaire   +3 more sources

Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs. [PDF]

, 2013
OBJECTIVES: Trypanosoma brucei drug transporters include the TbAT1/P2 aminopurine transporter and the high-affinity pentamidine transporter (HAPT1), but the genetic identity of HAPT1 is unknown. We recently reported that loss of T.
Aguinaga Andrés, David, Baker, Nicola, Barrett, Michael P, Burchmore, Richard JS, Clucas, Caroline, De Koning, Harry P, Eze, Anthonius A, Glover, Lucy, Graf, Fabrice E, Horn, David, Lee, Rebecca S, Ludin, Philipp, MacLeod, Annette, McDonald, Jennifer, Munday, Jane C, Mäser, Pascal, Natto, Manal J, Tait, Andy, Teka, Ibrahim A, Turner, C Michael R   +19 more
core   +4 more sources

The detection and treatment of human African trypanosomiasis

Research and Reports in Tropical Medicine, 2012
Bernard Bouteille,1 Alain Buguet21Laboratory of Parasitology, Dupuytren University Hospital of Limoges, France; 2Polyclinic Marie-Louise Poto-Djembo, Pointe-Noire, CongoAbstract: Human African trypanosomiasis (HAT) is caused by the injection of ...
Bouteille B, Buguet A
doaj  

Monitoring the use of nifurtimox-eflornithine combination therapy (NECT) in the treatment of second stage gambiense human African trypanosomiasis

Research and Reports in Tropical Medicine, 2012
Jose R Franco,1 Pere P Simarro,1 Abdoulaye Diarra,2 Jose A Ruiz-Postigo,3 Mireille Samo,1 Jean G Jannin11World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland; 2World Health ...
Franco JR, Simarro PP, Diarra A, Ruiz-Postigo JA, Samo M, Jannin JG   +5 more
doaj  

Effectiveness of a 10-Day Melarsoprol Schedule for the Treatment of Late-Stage Human African Trypanosomiasis: Confirmation from a Multinational Study (Impamel II) [PDF]

, 2017
BackgroundTreatment of late-stage human African trypanosomiasis (HAT) with melarsoprol can be improved by shortening the regimen. A previous trial demonstrated the safety and efficacy of a 10-day treatment schedule.
Asumu, Pedro N., Bilenge, Constantin Miaka Mia, Burri, Christian, Chappuis, Francois, Doua, Félix, Josenando, Théophile, Manthelot, Claude R., Nangouma, Auguste, Richer, Michaleen, Schmid, Caecilia, Simarro, Pere P.   +10 more
core  

Polyamine Metabolism for Drug Intervention in Trypanosomatids

Pathogens
Neglected tropical diseases transmitted by trypanosomatids include three major human scourges that globally affect the world’s poorest people: African trypanosomiasis or sleeping sickness, American trypanosomiasis or Chagas disease and different types of
Yolanda Pérez-Pertejo, Carlos García-Estrada, María Martínez-Valladares, Sankaranarayanan Murugesan, Rosa M. Reguera, Rafael Balaña-Fouce   +5 more
doaj   +1 more source

Nifurtimox-Eflornithine Combination Therapy for Second-Stage Gambiense Human African Trypanosomiasis: Médecins Sans Frontières Experience in the Democratic Republic of the Congo [PDF]

, 2017
Since 2009, nifurtimox-eflornithine combination therapy (NECT) has raised great hopes for the treatment of second-stage human African trypanosomiasis.
Alirol, Emilie, Amici Heradi, Josué, Chappuis, François, de Patoul, Catherine, Quere, Michel, Riedel, Andrea, Schrumpf, David   +6 more
core  

Poster Awards of the 4th Intercontinental Meeting of Hair Research Societies**Six poster awards, three for clinical and three for experimental hair research, were generously sponsored by Pfizer Consumer Health Care. [PDF]

, 1906
Tipografía de Noticiero de Vigo
core   +1 more source