Results 191 to 200 of about 741,060 (264)

CT-based radiomics and deep learning to predict EGFR mutation status in lung adenocarcinoma. [PDF]

Front Oncol
Jiang X, Sun Q, Wang C, Li W, Chen W, Xu J, Yu L.   +6 more
europepmc   +1 more source

Progression and prognostic significance of electrocardiographic findings in patients with cardiac amyloidosis

ESC Heart Failure, Volume 12, Issue 2, Page 809-818, April 2025.
Abstract Aims This study aimed to evaluate the change of the main electrocardiographic (ECG) characteristics and their prognostic role across the main subtypes of cardiac amyloidosis [light‐chain amyloidosis (AL) and hereditary (ATTRv) and wild‐type transthyretin amyloidosis (ATTRwt)].
Alessia Argirò, Mattia Zampieri, Carlotta Mazzoni, Carlo Fumagalli, Michela Baccini, Alessandra Mattei, Alberto Cipriani, Laura De Michieli, Aldostefano Porcari, Gianfranco Sinagra, Marco Merlo, Giacomo Tini, Beatrice Musumeci, Domitilla Russo, Pier Filippo Vianello, Marco Canepa, Roberto Licordari, Gianluca di Bella, Claudio Rapezzi, Federico Perfetto, Francesco Cappelli   +20 more
wiley   +1 more source

In-Silico Predictions of Drug Resistance in Lung Cancers With EGFR Mutation. [PDF]

Proc Platf Adv Sci Comput Conf
Imam I, Abbas UL, Gosser CM, Brainson CF, de Jong W, Liu X, Moseley HNB, Qing S, Zhang S, Zinner R, Ellingson SR.   +10 more
europepmc   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

NSCLC EGFR Mutation Prediction via Random Forest Model: A Clinical-CT-Radiomics Integration Approach. [PDF]

Adv Respir Med
Benfares A, Alami B, Boukansa S, Qjidaa M, Benomar I, Serraj M, Lakhssassi A, Jamil MO, Maaroufi M, Qjidaa H.   +9 more
europepmc   +1 more source

ER‐Localized Deadenylase PNLDC1 Suppresses Colorectal Cancer Progression by Targeting the mRNA Decay of TUBB4B

Exploration, EarlyView.
The deficiency of PNLDC1 exacerbates the advancement of CRC. PNLDC1 interacts with TUBB4B mRNA to regulate the p53–p21–CDK2–cyclin E2 pathway, thereby influencing the G2/M phase of the cell cycle. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related mortality, highlighting the urgent need for novel therapeutic strategies.
Lexin Liu, Yuelin Guan, Yuzhou Qin, Guiping Chen, Guozhen Wang, Xiang Yan, Xue Li, Lei Sun, Wei Yu, Shi Ouyang, Zhichao Ma, Zihao Xu, Zhongkai Cao, Fan Yu, Tong Zhou, Ziyou Luo, Xiangjun Chen, Yongbin Yan, Lidan Hu   +18 more
wiley   +1 more source

AKT Inhibitor Capivasertib as a Target for Osimertinib Combination Therapy in Lung Adenocarcinoma with <i>EGFR</i> Mutation. [PDF]

Genes (Basel)
Tokunaga T, Ishihara Y, Takeda AH, Tomioka Y, Nagata A, Kato M, Suetsugu T, Mizuno K, Ueda K, Seki N.   +9 more
europepmc   +1 more source

Case Report: Successful conversion surgery following chemo-antiangiogenic therapy in a lung adenocarcinoma patient with active rheumatoid arthritis and rare EGFR mutation after immunotherapy-triggered flare. [PDF]

Front Oncol
Ma J, Yan P, Liu C, Wang Y.
europepmc   +1 more source

Gene signatures characterizing driver mutations in lung squamous carcinoma are predictive of the progression of pre‐cancer lesions

International Journal of Cancer, EarlyView.
What's New? Lung squamous cell carcinoma (LUSC) is more aggressive than lung adenocarcinoma, and is most often diagnosed at an advanced stage. Here, the authors evaluated gene expression data from LUSC tumors and came up with gene signatures for 34 genetic abnormalities whose expression changes throughout different precancerous stages. Several of these
Yupei Lin, Venugopalareddy Mekala, Jianrong Li, Xiang Wang, Muhammad Aminu, Jia Wu, Jianjun Zhang, Robert Taylor Ripley, Christopher I. Amos, Chao Cheng   +9 more
wiley   +1 more source

Updated incidence of EGFR mutation in Middle Eastern patients with non-small cell lung cancer: a 7-year study in a Lebanese institution. [PDF]

BMC Cancer
Kourie HR, Farhat C, Zouein J, Chebly A, Noujeim F, Riachy M, Dabar G, Harmouche C, Haber B, Bacha ZA, Kattan J, Nasr F, Chahine G, Ghosn M, Trak-Smayra V, ElKarak F, Kesrouani C.   +16 more
europepmc   +1 more source