Results 171 to 180 of about 741,060 (264)

Case Report: SMARCA4-deficient non-small cell lung cancer - effective local control with radiotherapy and emergence of a targetable EGFR mutation. [PDF]

Front Oncol
Luo J, Lin S, Wang M, Zeng Y, Tang W.
europepmc   +1 more source

The potential impact of H1 antihistamines on clinical outcomes in NSCLC patients undergoing EGFR‐TKIs treatment

British Journal of Clinical Pharmacology, EarlyView.
Background Epidermal growth factor receptor–tyrosine kinase inhibitors (EGFR‐TKIs) have substantially improved outcomes in non‐small cell lung cancer (NSCLC); however, the development of treatment resistance remains a major clinical challenge. This study examines the association between concomitant prescriptions of H1‐antihistamines (H1AHs) and ...
Van Thuan Nguyen, Ngoc Hoang Le, Nhu Quynh Phan, Toan Trung Duong, Le Thi Anh Thu, Hsuan‐Chia Yang, Chih‐Wei Huang, Min‐Huei Hsu, Jason C. Hsu, Chien‐Tien Su, Phung‐Anh Nguyen   +10 more
wiley   +1 more source

Analyse molekularpathologischer Faktoren des EGFR-Signalwegs und ihre Bedeutung als prädiktive Faktoren in der Behandlung des metastasierten kolorektalen Karzinoms mit dem EGFR-Antikörper Cetuximab [PDF]

, 2013
Kapaun, Christine
core   +1 more source

Treatment options and considerations for acquired resistance in EGFR mutation-positive non-small-cell lung cancer. [PDF]

ESMO Open
Le X, Popat S, Heymach JV, West H, Zhang L.   +4 more
europepmc   +1 more source

CYP3A5 genetic variability influences sildenafil and metabolite in pulmonary hypertension

British Journal of Clinical Pharmacology, EarlyView.
Aim Interindividual variability in sildenafil response among pulmonary hypertension patients (PH) may be influenced by CYP3A5 polymorphisms. CYP3A5*3 allele reduces CYP3A5 activity and affects sildenafil metabolism. This study investigated the associations between CYP3A5 genotype and plasma concentrations of sildenafil and N‐desmethyl sildenafil, as ...
Pranisa Wongwien, Burabha Pussadhamma, Sirimas Kanjanawart, Thikhumporn Areesinpitak, Nontaya Nakkam, Chingching Foocharoen, Wichittra Tassaneeyakul, Suda Vannaprasaht   +7 more
wiley   +1 more source

A Rare Case of Anti-Yo Antibody Positive Paraneoplastic Neurologic Syndromes With EGFR Mutation Positive Non-Small Cell Lung Cancer. [PDF]

Respirol Case Rep
Okagaki N, Ueyama M, Fujimoto S, Iwagaki S, Sakamoto H, Tanaka Y, Nakanishi T, Nakamura S, Matsumura K, Ikegami N, Kaji Y, Hashimoto S, Tanaka E, Taguchi Y, Fukunaga A, Suenaga T, Kanamori N, Kubo T, Hajiro T.   +18 more
europepmc   +1 more source

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu, Zeynep Betül Sarı, Muhammed Emin Sarı, Erdi Can Aytar   +3 more
wiley   +1 more source

Deep Learning Predicts EGFR Mutation Status from Histology Images in Non-Small Cell Lung Cancer. [PDF]

Cancer Res Commun
Park J, Shin S, Hwang W, Keum S, Brattoli B, Rawson JH, Lee T, Pereira S, Ahn CH, Senior MJT, Qaiser T, Kim S, Kim H, Chung JH, Choi YL, Lee SH, Bannister H, Riboni-Verri E, Ock CY, Hill RJ, Ali S, Moore L.   +21 more
europepmc   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Prediction of EGFR mutation status and mutation sites in lung cancer based on radiomics and deep learning. [PDF]

J Thorac Dis
Zeng Z, Zhang R, Dong Y, Liu B, Ma H, Zheng Y, Gao X, Li Q.   +7 more
europepmc   +1 more source