Results 161 to 170 of about 741,060 (264)

An extremely rare case of congenital pulmonary airway malformation (CPAM) and atypical adenomatous hyperplasia (AAH) with EGFR mutation in a five-year-old girl. [PDF]

BMC Pediatr
Liu X, Zhaxi C, Yang S, Jiang L, Zhou P.
europepmc   +1 more source

EGFR mutations tested, target concentrations, and OPA for each EGFR mutation.

EGFR mutations tested, target concentrations, and OPA for each EGFR mutation.
Jason Lai (44092), Theresa May (18334177), Sidney Scudder (12475550), Snehal Joshi (18334189), Michelle S. Clement (9560905), Alexander Kohlmann (76969), Patrick O’Donnell (3557501), Peter Meldgaard (4858900), Xiaocheng Li-Sucholeiki (15014244), Milena Kohlmann (18334183), Harkanwal Halait (18334180), Neelima Shrestha (18334192), Marilyn Kiral (18334195), Nitta Lee (18334186), Boe Sorensen (4858906)   +14 more
core   +1 more source

Growth Differentiation Factor 15 as a Cerebrospinal Fluid Biomarker for the Diagnosis and Prognosis of Leptomeningeal Metastasis

Annals of Neurology, EarlyView.
Objective As leptomeningeal metastasis (LM) has a poor prognosis, reliable cerebrospinal fluid (CSF) diagnostic biomarkers are urgently needed. This study evaluated the diagnostic value of CSF growth differentiation factor 15 (GDF15) in LM from lung adenocarcinoma (LUAD) and breast cancer (BC).
Haoyu Ruan, Jie Li, Fuhai Wang, Lei Zhang, Jie Luo, Yuan Mu, Ting Wang, Yuqing Wu, Jingping Liu, Yunyun Ning, Xuan Deng, Ming Guan, Jian Xu   +12 more
wiley   +1 more source

Deep learning framework for predicting EGFR mutation status from H&E whole slide images in lung adenocarcinoma. [PDF]

BMC Cancer
Shao W, Gu W, Song S, Chen D, Shao Z, Sun Q, Yu H.   +6 more
europepmc   +1 more source

A Case of Lung Adenocarcinoma With Concurrent EGFR Mutation and ALK Fusion Combined With Literature Review. [PDF]

Clin Case Rep
Chen Y, Qi F, Zeng Y, Tan J, Hu M, Zhang H, Zhang T.   +6 more
europepmc   +1 more source

Development and validation of a PET/CT radiomics and dual-task learning model for the prediction of pathological subtypes and EGFR mutation in non-small cell lung cancer. [PDF]

Transl Lung Cancer Res
Jiang F, Zhang NF, Gao Y, Chen X, Liu ET, Mou T.   +5 more
europepmc   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Establishment of a Flow Cytometry Protocol for Binarily Detecting Circulating Tumor Cells with EGFR Mutation. [PDF]

Diseases
Chang CY, Tu CC, Lin SR, Fang CH, Tseng PW, Liao WE, Huang LY, Wang SL, Lai WY, Chao Y, Chiu YL, Lee JM.   +11 more
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source