Results 31 to 40 of about 741,060 (264)

EGFR-TKI Sensitizing Mutation Rate in Adenocarcinoma of Lung

Pakistan Armed Forces Medical Journal, 2023
Objective: To assess EGFR-TKI sensitizing mutation rate in patients having lung adenocarcinoma and its association with smoking status. Study Design: Cross-sectional study.
Sana Sehar, Ghulam Haider, Berkha Rani, Versha Rai, Tooba Ather, Batool Memon   +5 more
doaj   +1 more source

Analysis of Epithelial Growth Factor-Receptor (EGFR) Phosphorylation in Uterine Smooth Muscle Tumors [PDF]

, 2013
Uterine fibroids are the commonest uterine benign tumors. A potential mechanism of malignant transformation from leiomyomas to leiomyosarcomas has beendescribed.
Darius Dian, Antonis Makrigiannakis, Jeschke, Udo, Klaus Friese, Weissenbacher, Tobias, Mayr, Doris, David Roeder, Udo Jeschke, Nina Ditsch, Thomas Vrekoussis, Tobias Weissenbacher, Vrekoussis, Thomas, Dian, Darius, Ditsch, Nina, Friese, Klaus, Doris Mayr, Makrigiannakis, Antonis, Roeder, David   +17 more
core   +1 more source

Correlation Analysis of Ki67 Expression and EGFR Mutation on the Risk of Recurrence and Metastasis in Postoperative Patients with Stage I Lung Adenocarcinoma

Chinese Journal of Lung Cancer, 2022
Background and objective The prognosis of stage I non-small cell lung cancer (NSCLC) is generally good. However, some of the stage I NSCLC patients still may have early recurrence and metastasis, and there is no standard method to screen this part of the
Lili XU, Renhua GUO
doaj   +1 more source

Modest effect of p53, EGFR and HER-2/neu on prognosis in epithelial ovarian cancer: a meta-analysis [PDF]

, 2009
Background: P53, egfr and her-2/neu are the most frequently studied molecular biological parameters in epithelial ovarian cancer, but their prognostic impact is still unequivocal.
de Jong, S., de Vries, E.G.E., de Bock, G.H.; id_orcid, Boezen, M., Post, W.J., van der Zee, A.G.J., de Vries, E.G.E.; id_orcid, Crijns, A.P.G., de Jong, S.; id_orcid, de Graeff, P., de Bock, G.H.   +10 more
core   +2 more sources

Survival Analysis of 159 Patients With Advanced Non-Small-Cell Lung Cancer Resistant to First-Generation Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor

Clinical Medicine Insights: Oncology, 2023
Background: Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) have limited or no response in some certain patients of non-small-cell lung cancer (NSCLC).
Aimin Hu, Kun Li, Hua Zheng, Haitao Rao, Tongmei Zhang, Baolan Li   +5 more
doaj   +1 more source

Growth Suppression in Lung Cancer Cells Harboring EGFR-C797S Mutation by Quercetin

Biomolecules, 2021
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are approved treatments for non-small-cell lung cancer (NSCLC) patients harboring activating EGFR mutations.
Kuo-Yen Huang, Tong-Hong Wang, Chin-Chuan Chen, Yann-Lii Leu, Hsin-Jung Li, Cai-Ling Jhong, Chi-Yuan Chen   +6 more
doaj   +1 more source

Trends in Overall Survival in Lung Adenocarcinoma with EGFR Mutation, KRAS Mutation, or No Mutation. [PDF]

Cancers (Basel)
Background: Treatment of lung adenocarcinoma has changed and now includes checkpoint inhibitors (CPIs) or, in the case of an EGFR mutation, third-generation EGFR TKI osimertinib.
Faehling M, Fallscheer S, Schwenk B, Seifarth H, Sträter J, Lengerke C, Christopoulos P.   +6 more
europepmc   +2 more sources

Survival of lung adenocarcinoma patients with malignant pleural effusion

, 2014
In the era of targeted therapy, the association between lung adenocarcinoma patient survival and malignant pleural effusions (MPEs) remains unclear. This study investigated the clinical characteristics, survival and epidermal growth factor receptor (EGFR)
楊志新 ;詹一秀 ;楊泮池 ;廖唯昱 ;余忠仁, Wu, Shang-Gin;Yu, Chong-Jen;Tsar, Meng-Feng;Liao, Wei-Yu;Yang, Chih-Hsin;Jan, I-Shiow;Yang, Pan-Chyr;Shin, Jin-Yuan   +1 more
core   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Apparent diffusion coefficient value of brain metastasis from lung carcinoma as potential predictor of epidermal growth factor receptor mutation

The Egyptian Journal of Radiology and Nuclear Medicine, 2023
Background Lung carcinoma metastases to the brain occurred in 40% of all lung carcinoma cases and it occupied the top ranking of mortality of cancers. MRI plays an important role in predicting mutations of lung carcinoma.
Muchtar Hanafi, Rachmi Fauziah Rahayu, Tonang Dwi Ardyanto   +2 more
doaj   +1 more source