Results 41 to 50 of about 111,930 (282)

Microneme Protein 6 Is Involved in Invasion and Egress by Neospora caninum

Pathogens, 2021
Background: Neospora caninum, is the etiological agent of neosporosis, an infection that causes abortions in cattle and nervous system dysfunction in dogs. Invasion and egress are the key steps of the pathogenesis of N. caninum infection.
Xianmei Wang, Di Tang, Fei Wang, Gaowei Jin, Lifang Wang, Qun Liu, Jing Liu   +6 more
doaj   +1 more source

Herpesvirus Assembly and Egress [PDF]

Journal of Virology, 2002
Herpesvirus particles consist of four morphologically distinct structures, the core, capsid, tegument, and envelope. The inner nucleoprotein core comprising the linear double-stranded DNA genome is included in an icosahedral (T=16) capsid shell of 150 hexons and 12 pentons.
openaire   +2 more sources

BGP-like TE Capabilities for SHIM6 [PDF]

, 2006
In this paper we present a comprehensive set of mechanisms that restore to the site administrator the capacity of enforcing traffic engineering (TE) policies in a multiaddressed IPv6 scenario.
Azcorra, Arturo, Bagnulo Braun, Marcelo Gabriel, García-Martínez, Alberto   +2 more
core   +4 more sources

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Applying the lessons of the attack on the World Trade Center, 11th September 2001, to the design and use of interactive evacuation simulations [PDF]

, 2005
The collapse of buildings, such as terminal 2E at Paris' Charles de Gaule Airport, and of fires, such as the Rhode Island, Station Night Club tragedy, has focused public attention on the safety of large public buildings.
Johnson, C.W.
core   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

XMM-Newton X-ray spectroscopy of the high-mass X-ray binary 4U1700-37 at low flux [PDF]

, 2004
We present results of a monitoring campaign of the high-mass X-ray binary system 4U 1700-37/HD 153919, carried out with XMM-Newton in February 2001. The system was observed at four orbital phase intervals, covering 37% of one 3.41-day orbit.
A. van der Meer, Ankay, Ballet, Barziv, Bautista, Blondin, Boroson, Boroson, Brown, Burderi, Clark, den Herder, Drake, Dupree, Ebisawa, Goldstein, Gottwald, Haberl, Haberl, Haberl, Haberl, Hatchett, Hayakawa, Heap, Hickox, Hutchings, in 't Zand, Jansen, Johnson, Jones, Kaastra, Kaper, Kaper, Kaper, Kaper, Kilian, L. Kaper, La Barbera, Liu, Lotz, M. Méndez, M. van der Klis, Mason, Morrison, N. R. Trams, Nagase, Nagase, P. Barr, Paerels, Quaintrell, Reynolds, Rubin, Sako, Schaller, Schulz, Strüder, T. Di Salvo, Tarter, Trümper, Turner, van Loon, Vink, Vink, Watanabe, White, Wojdowski   +65 more
core   +2 more sources

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

Cytoplasmic free Ca²⁺ is essential for multiple steps in malaria parasite egress from infected erythrocytes

Malaria Journal, 2013
Background Egress of Plasmodium falciparum, from erythrocytes at the end of its asexual cycle and subsequent parasite invasion into new host cells, is responsible for parasite dissemination in the human body.
Glushakova Svetlana, Lizunov Vladimir, Blank Paul S, Melikov Kamran, Humphrey Glen, Zimmerberg Joshua   +5 more
doaj   +1 more source

An Endoplasmic Reticulum CREC Family Protein Regulates the Egress Proteolytic Cascade in Malaria Parasites

mBio, 2020
The endoplasmic reticulum (ER) is thought to play an essential role during egress of malaria parasites because the ER is assumed to be required for biogenesis and secretion of egress-related organelles.
Manuel A. Fierro, Beejan Asady, Carrie F. Brooks, David W. Cobb, Alejandra Villegas, Silvia N. J. Moreno, Vasant Muralidharan   +6 more
doaj   +1 more source