Results 81 to 90 of about 111,930 (282)

Characterising exo-ringsystems around fast-rotating stars using the Rossiter-McLaughlin effect [PDF]

open access: yes, 2017
Planetary rings produce a distinct shape distortion in transit lightcurves. However, to accurately model such lightcurves the observations need to cover the entire transit, especially ingress and egress, as well as an out-of-transit baseline.
de Mooij, E. J. W.   +2 more
core   +3 more sources

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Traffic Engineering with Segment Routing: SDN-based Architectural Design and Open Source Implementation

open access: yes, 2015
Traffic Engineering (TE) in IP carrier networks is one of the functions that can benefit from the Software Defined Networking paradigm. By logically centralizing the control of the network, it is possible to "program" per-flow routing based on TE goals ...
Davoli, Luca   +4 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Structural Features of Apicomplexan Pore-Forming Proteins and Their Roles in Parasite Cell Traversal and Egress

open access: yesToxins, 2017
Apicomplexan parasites cause diseases, including malaria and toxoplasmosis, in a range of hosts, including humans. These intracellular parasites utilize pore-forming proteins that disrupt host cell membranes to either traverse host cells while migrating ...
Alfredo J. Guerra, Vern B. Carruthers
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Host and Viral Proteins Modulating Ebola and Marburg Virus Egress

open access: yesViruses, 2019
The filoviruses Ebolavirus and Marburgvirus are among the deadliest viral pathogens known to infect humans, causing emerging diseases with fatality rates of up to 90% during some outbreaks.
Tamsin B. Gordon   +4 more
doaj   +1 more source

Detecting transit signatures of exoplanetary rings using SOAP3.0 [PDF]

open access: yes, 2017
CONTEXT. It is theoretically possible for rings to have formed around extrasolar planets in a similar way to that in which they formed around the giant planets in our solar system. However, no such rings have been detected to date. AIMS: We aim to test
Akinsanmi, B.   +3 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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