Results 151 to 160 of about 73,550 (267)

Mathematical Model of \u3cem\u3eChlorella minutissima\u3c/em\u3e UTEX2341 Growth and Lipid Production Under Photoheterotrophic Fermentation Conditions [PDF]

To reduce the cost of algal biomass production, mathematical model was developed for the first time to describe microalgae growth, lipid production and glycerin consumption under photoheterotrophic conditions based on logistic, Luedeking–Piret and ...
Hristova, Krassimira R., Rasa, Ehsan, Scow, Kate M., Tantayotai, Prapakorn, Yang, Jinshui, Yuan, Hong Li   +5 more
core  

Fatty Acid Metabolism in Health and Cancer: From Fundamental Mechanisms to Therapeutic Application

MedComm, Volume 7, Issue 6, June 2026.
The modulation of the TME by fatty acid metabolism primarily occurs through four key pathways: inflammation regulation, signal transduction, translation to TME, and oxidative stress. ABSTRACT Fatty acid metabolism (FAM) plays a vital role in maintaining health by supporting energy production, cellular structure, and signaling processes.
Na Hang, Runkang Zhao, Fan Zhang, Dandan Guo, Qing Li, Zhijun Shen, Ruiqing Gao, Chenyu Gao, Zhao Xie, Sentao Fu, Peng Luo, Bufu Tang, Ling Wang   +12 more
wiley   +1 more source

ω‐3PUFAs Inhibit Gallbladder Cancer Through Enhancing STK31 Methylation

Molecular Nutrition &Food Research, Volume 70, Issue 11, 15 June 2026.
ABSTRACT Gallbladder cancer (GBC) is an aggressive malignancy with limited treatment options. ω‐3PUFAs have known anticancer activity, but their role in GBC remains unclear. The anti‐GBC effects of ω‐3PUFAs (DHA/EPA) were evaluated using in vitro assays and mouse xenograft models.
Shuang‐Xing Li, Wei‐Yu Zhu, Hai‐Ying Peng, Bin Zhang, Zhu‐Ying Lin, Song‐Lin Yang, Yi‐Yi Zhao, Hui Gao, Shan He, Yuan Liu, Xiao‐Dan Wang, Yang‐Fan Guo, Wen‐Ju Wang, Zong‐Liu Hou, Ming‐Yao Meng, Li‐Wei Liao, Lin Li   +16 more
wiley   +1 more source

Acute Hypercapnia/Ischemia Alters the Esterification of Arachidonic Acid and Docosahexaenoic Acid Epoxide Metabolites in Rat Brain Neutral Lipids. [PDF]

In the brain, approximately 90% of oxylipins are esterified to lipids. However, the significance of this esterification process is not known. In the present study, we (1) validated an aminopropyl solid phase extraction (SPE) method for separating ...
Bazinet, Richard P, Hammock, Bruce D, Metherel, Adam H, Newman, John W, Otoki, Yurika, Pedersen, Theresa, Taha, Ameer Y, Yang, Jun   +7 more
core  

Peroxisomal Lipid Metabolism as a Therapeutic Target in Leukemia

Molecular Nutrition &Food Research, Volume 70, Issue 11, 15 June 2026.
Peroxisomes are emerging as key regulators of lipid metabolism in leukemia. Enhanced metabolism of very‐long‐chain fatty acids (VLCFAs) supports leukemia cell survival, redox homeostasis, and therapeutic resistance. Pharmacologic disruption of peroxisomal fatty acid oxidation causes VLCFA accumulation, oxidative stress, and mitochondrial dysfunction ...
Ekaterina N. Parfenova, Paul A. Spagnuolo   +1 more
wiley   +1 more source

Omega‐3 DHA as a blank canvas: A molecular approximation to how lipid mediators modulate LGR6 in inflammation resolution

Protein Science, Volume 35, Issue 6, June 2026.
Abstract The leucine‐rich repeat‐containing G protein‐coupled receptor 6 (LGR6) has a potential role in inflammation resolution and different cancer processes. In this study, we employed computational techniques, including molecular docking and molecular dynamics simulations of mammalian membrane‐embeded systems, to understand the activation mechanism ...
Álex Pérez‐Sánchez, Mireia Garcia‐Viloca, Àngels González‐Lafont, José M. Lluch   +3 more
wiley   +1 more source

Physiological doses of eicosapentaenoic acid suppress high-fat diet-induced atrial fibrillation in mice independent of lipid lowering. [PDF]

J Physiol Sci
Horii K, Ono K, Masuda S, Morishima M.
europepmc   +1 more source

Meta Analysis of DHA and EPA Supplementation on Cardiovascular Outcomes and Atrial Fibrillation Risk

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Cardiovascular diseases (CVD) remain to impose a main global burden of morbidity and mortality despite advances in anticipation and treatment. Omega‐3 fatty acids, mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been extensively studied for potential cardioprotective effects, yet their impact on cardiovascular outcomes ...
Sepideh Karkon Shayan, Rosull Saadoon Abbood, Sarah F. Al‐Taie, Paria Ganji Nataj, Maksudova Malika Khamdamjonovna, Siamak Aminnezhad, Yasaman Ghodsi Boushehri, Jabbarov Jamoliddin Sindorovich, Ali Sinehsepehr, Farshad Zare, Seyed Abbas Pakmehr, Elham Abdollahi, Milad Vahedinezhad   +12 more
wiley   +1 more source

Maternal docosahexaenoic acid and eicosapentaenoic acid supplementation: effects and mechanisms on lipid metabolism in the offspring. [PDF]

Front Nutr
Shao C, Lin H, Yu J, Chen H, Ren Y, Ren J, Zeng Y, Wu Y, Zhang Q, Xiao X.   +9 more
europepmc   +1 more source

Maternal Intake of Dipteryx alata Vog. Reduces Offspring's Brain Oxidative Stress and Anxiety: Insights From In Silico and In Vivo Studies

Journal of Food Science, Volume 91, Issue 6, June 2026.
ABSTRACT We undertook a computational investigation and evaluation of the impact of maternal supplementation with baru almonds (Dipteryx alata Vog.) on anxiety‐like behavior and oxidative stress in the brains of adolescent and adult rat offspring. Molecular docking studies were conducted and revealed that the phenolic compounds (PCs) from the baru ...
Diego Elias Pereira, Rita de Cássia de Araújo Bidô, Maciel da Costa Alves, Renally de Lima Moura, Ana Carolina dos Santos Costa, Larissa Maria Gomes Dutra, Louis Gustavo da Costa Sobral e Sá, Vanessa Bordin Viera, Jaqueline Ferreira Ramos, Juliano Carlo Rufino Freitas, Daline Fernandes de Araújo, Gerlane Coelho Bernardo Guerra, Juliana Késsia Barbosa Soares   +12 more
wiley   +1 more source