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Effect of eicosapentaenoic acid in asthma
Clinical & Experimental Allergy, 1988SummaryThe role of arachidonic acid metabolites in the pathogenesis of airway inflammation and clinical asthma is currently unknown. The addition of eicosapentaenoic acid (EPA) to the diet of humans has been shown to generate metabolites that are less potent than their arachidonic acid counterparts.
C M, Kirsch +8 more
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Stearidonic acid as a ‘pro-eicosapentaenoic acid’
Current Opinion in Lipidology, 2012ω-3 Fatty acids continue to be promoted as cardioprotective, generating an increased demand for these nutrients. Ocean-based supplies are limited, and so land-based sources are being sought. Stearidonic acid-fortified soybean oil may help to meet this demand.Stearidonic acid has been shown in animal and human studies to be more effective than its ...
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Eicosapentaenoic acid and chemoprevention of FAP
Gut, 2010In this issue of Gut , West et al 1 report positive results of a chemoprevention trial in British subjects with familial adenonomatous polyposis (FAP) ( see page 918 ). There is a long history of use of natural products in FAP and other adenoma prevention trials.2 4 In most cases the rationale seems predicated on notions of likely safety and ...
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Production of Eicosapentaenoic Acid by Marine Bacteria
The Journal of Biochemistry, 1988About 5,000 strains of marine microorganisms were screened for eicosapentaenoic acid (EPA)-producing ability, which was detected in 88 of them. All of the latter were found to be obligate aerobic, Gram-negative, motile, short rod-shaped bacteria. One strain, designated as SCRC-8132, showed a doubling time of 30 min at 25 degrees C and produced 20 mg ...
K, Yazawa +7 more
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The collembolan Sinella dubiosa produces eicosapentaenoic acid
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biologyn-3 polyunsaturated fatty acids (n-3 PUFAs), including eicosapentaenoic acid (EPA), are essential nutrients for vertebrate development and physiology. Microorganisms, such as microalgae, produce n-3 PUFAs that are transferred to higher predators in the aquatic food web.
Yuya, Ohhara +2 more
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Tumour fatty acid metabolism in the context of therapy resistance and obesity
Nature Reviews Cancer, 2021Andrew J Hoy +2 more
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