Results 41 to 50 of about 4,987,765 (222)

Meteoritic Abundances of Fatty Acids and Potential Reaction Pathways in Planetesimals [PDF]

open access: yesIcarus, 2019, 319, 685-700, 2018
The origin of fatty acids on the prebiotic Earth is important as they likely formed the encapsulating membranes of the first protocells. Carbon-rich meteorites (i.e., carbonaceous chondrites) such as Murchison and Tagish Lake are well known to contain these molecules, and their delivery to the early planet by intense early meteorite bombardments ...
arxiv   +1 more source

Eicosapentaenoic acid attenuates obesity-related hepatocellular carcinogenesis

open access: yesCarcinogenesis, 2017
By using a carcinogen-injected dietary obesity model, we demonstrated that eicosapentaenoic acid attenuated the development of hepatocellular carcinoma associated with obesity by inhibiting the activation of STAT3 and subsequent tumor cell proliferation ...
Akane Inoue-Yamauchi, H. Itagaki, H. Oda
semanticscholar   +1 more source

Efficient One‐Step Production of 7S,17S‐ and 10S,17S‐Dihydroxydocosahexaenoic Acids by a Double‐Oxygenating 15S‐Lipoxygenase From Chlamydomonas incerta

open access: yesBiotechnology and Bioengineering, EarlyView.
Biotransformation pathway from polyunsaturated fatty acids into dihydroxy fatty acids as lipid mediators by Escherichia coli expressing Chlamydomonas incerta 15S‐lipoxygenase with double oxygenating activity. The 15S‐lipoxygenase was the most efficient for the simultaneous production of resolvin D5 (7S,17S‐dihydroxydocosahexaenoic acid, 7S,17S‐DiHDHA ...
Hyun‐Ah Park, Jin Lee, Deok‐Kun Oh
wiley   +1 more source

Bioactives From Brown Algae: Antioxidant, Anti‐Inflammatory, Anticancer, and Antimicrobial Potential

open access: yesChemBioEng Reviews, EarlyView.
This review explores key bioactives in brown algae and their antioxidant, anti‐inflammatory, anticancer, and antimicrobial properties. Covering studies from 2014 to 2024, it highlights their relevance in pharmaceuticals, nutraceuticals, cosmetics, and foods, while addressing challenges and future directions to unlock their full potential.
Irvin Fonseca‐Barahona   +2 more
wiley   +1 more source

Differential effects of eicosapentaenoic acid and oleic acid on lipid synthesis and secretion by HepG2 cells.

open access: yesJournal of Lipid Research, 1991
The effects of eicosapentaenoic acid and oleic acid on lipid synthesis and secretion by HepG2 cells were examined to identify fatty acid specific changes in lipid metabolism that might indicate a basis for the hypolipidemic effect attributed to ...
R Homan, JE Grossman, HJ Pownall
doaj  

Rapeseeds a Rich Source of Polyunsaturated Fatty Acids

open access: yesProceedings, 2019
In human diet, polyunsaturated fatty acids (PUFA), have an essential role in optimal brain functions and stroke prevention, specially, omega-3 fatty acids, e.g., 9,12,15-linolenic acid (ALA, 18:3), 5,8,11,14,17-eicosapentaenoic acid (EPA, 20:5), and 4,7 ...
Cristina Emanuela Enăşcuţă   +7 more
doaj   +1 more source

Habitual Fish Consumption, n‐3 Fatty Acids, and Nuclear Magnetic Resonance Lipoprotein Subfractions in Women

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Supplementation with omega‐3 (n‐3) fatty acid or dietary fish may protect against atherosclerosis, but the potential mechanisms are unclear.
Nuria Amigó   +5 more
doaj   +1 more source

Lipid Metabolism and Immune Function: Chemical Tools for Insights into T‐Cell Biology

open access: yesChemBioChem, EarlyView.
This review explores how lipids regulate immune responses, particularly in T‐cell function. Advances in metabolomics and proteomics provide insights into lipid‐mediated immunity. Fluorescent lipids enable single‐cell analysis of lipid uptake and metabolism.
Luuk Reinalda   +2 more
wiley   +1 more source

Sustainable source of omega-3 eicosapentaenoic acid from metabolically engineered Yarrowia lipolytica: from fundamental research to commercial production

open access: yesApplied Microbiology and Biotechnology, 2015
The omega-3 fatty acids, cis-5, 8, 11, 14, and 17-eicosapentaenoic acid (C20:5; EPA) and cis-4, 7, 10, 13, 16, and 19-docosahexaenoic acid (C22:6; DHA), have wide-ranging benefits in improving heart health, immune function, mental health, and infant ...
D. Xie, E. Jackson, Q. Zhu
semanticscholar   +1 more source

Total Synthesis of Ectocarpin A

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A fully enantioselective total synthesis of ectocarpin A, a new oxylipin, has been achieved in 12 steps starting from tetrahydro‐1H‐cyclopentafuranone. Key steps include the formation of the chiral core, diastereoselective epoxidation, enzymatic desymmetrization of a 1,4‐diol, epimerization, and strategic Wittig and Julia‐Kocienski olefinations to ...
Alexandre Guy   +2 more
wiley   +1 more source

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