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Severe hypertension in elapid envenomation [PDF]

open access: yesJournal of Cardiovascular Disease Research (discontinued), 2013
Snakebite is not an uncommon medical emergency in India; however, symptoms of autonomic dysfunction in snakebite are rare. The elapid snake envenomation is a frequent occurrence in India, and the krait bite is prevalent in the south Indian region. Here, we present three cases of snakebite with severe hypertension and requiring intravenous nitroglycerin
Martin Grootveld
exaly   +7 more sources

Distinct regulatory networks control toxin gene expression in elapid and viperid snakes [PDF]

open access: yesBMC Genomics
Background Venom systems are ideal models to study genetic regulatory mechanisms that underpin evolutionary novelty. Snake venom glands are thought to share a common origin, but there are major distinctions between venom toxins from the medically ...
Cassandra M. Modahl   +8 more
doaj   +4 more sources

Venom Down Under: Dynamic Evolution of Australian Elapid Snake Toxins [PDF]

open access: yesToxins, 2013
Despite the unparalleled diversity of venomous snakes in Australia, research has concentrated on a handful of medically significant species and even of these very few toxins have been fully sequenced.
Timothy N W Jackson   +2 more
exaly   +5 more sources

Rapid Radiations and the Race to Redundancy: An Investigation of the Evolution of Australian Elapid Snake Venoms [PDF]

open access: yesToxins, 2016
Australia is the stronghold of the front-fanged venomous snake family Elapidae. The Australasian elapid snake radiation, which includes approximately 100 terrestrial species in Australia, as well as Melanesian species and all the world's true sea snakes,
Timothy N W Jackson   +2 more
exaly   +5 more sources

Identification and Characterization of Novel Serpentoviruses in Viperid and Elapid Snakes [PDF]

open access: yesViruses
Viruses in the subfamily Serpentovirinae (order Nidovirales, family Tobaniviridae) can cause significant morbidity and mortality in captive snakes, but documented infections have been limited to snakes of the Boidae, Colubridae, Homalopsidae, and ...
Steven B. Tillis   +11 more
doaj   +4 more sources

Differential Effects of Marimastat and Prinomastat on the Metalloprotease Activity of Various Snake Venoms [PDF]

open access: yesToxins
Snakebite envenoming is a neglected tropical disease, responsible for approximately 140,000 deaths globally each year. Vipers and elapid snakes represent the most significant snake families in medical contexts, exhibiting a variety of venom components ...
Mahtab Khatibi   +6 more
doaj   +2 more sources

Effects of Cape Cobra (Naja nivea) Venom and Its Isolated Protein on the Modulation of Platelet Activation [PDF]

open access: yesToxins
The Cape cobra (Naja nivea), one of Africa’s most lethal snakes, can cause rapid, life-threatening paralysis. However, the impact of this venom on platelet function and blood coagulation remains poorly understood. To address this gap, we investigated the
Mahtab Khatibi   +5 more
doaj   +2 more sources

A Quest for a Universal Plasma-Derived Antivenom Against All Elapid Neurotoxic Snake Venoms

open access: yesFrontiers in Immunology, 2021
This review describes the research aimed at the development of universal antivenom against elapid neurotoxic snake venoms. The antivenoms produced in Thailand in the 1980s were of low potency, especially against the elapid venoms.
Kavi Ratanabanangkoon
exaly   +3 more sources

The evolution of scale sensilla in the transition from land to sea in elapid snakes [PDF]

open access: yesOpen Biology, 2016
Scale sensilla are small tactile mechanosensory organs located on the head scales of many squamate reptiles (lizards and snakes). In sea snakes and sea kraits (Elapidae: Hydrophiinae), these scale organs are presumptive scale sensilla that purportedly ...
Jenna M Crowe-Riddell   +2 more
exaly   +2 more sources

Profiling cytotoxicity of nanofractionated elapid snake venoms in human cell lines representing different tissues [PDF]

open access: yesJournal of Pharmaceutical Analysis
Elapid snakebites cause severe toxicity, predominantly neurotoxicity and general cytotoxicity. However, the specific cellular impacts of individual venom toxins remain largely underexplored.
Haifeng Xu   +5 more
doaj   +2 more sources

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