Results 1 to 10 of about 2,957 (202)
The macromolecular enzyme complex prothrombinase serves an indispensable role in blood coagulation as it catalyzes the conversion of prothrombin to thrombin, a key regulatory enzyme in the formation of a blood clot.
Mettine H.A. Bos, Rodney M. Camire
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Distinct regulatory networks control toxin gene expression in elapid and viperid snakes [PDF]
Background Venom systems are ideal models to study genetic regulatory mechanisms that underpin evolutionary novelty. Snake venom glands are thought to share a common origin, but there are major distinctions between venom toxins from the medically ...
Cassandra M. Modahl +8 more
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A Review and Database of Snake Venom Proteomes
Advances in the last decade combining transcriptomics with established proteomics methods have made possible rapid identification and quantification of protein families in snake venoms.
Theo Tasoulis, Geoffrey K. Isbister
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Diversification rates and phenotypic evolution in venomous snakes (Elapidae) [PDF]
The relationship between rates of diversification and of body size change (a common proxy for phenotypic evolution) was investigated across Elapidae, the largest radiation of highly venomous snakes.
Michael S. Y. Lee +3 more
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Background The cysteine-rich neurotoxins from elapid venoms are primarily responsible for human and animal envenomation; however, their low concentration in the venom may hamper the production of efficient elapid antivenoms.
Herlinda Clement +5 more
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Some Australian elapids possess potently procoagulant coagulotoxic venoms which activate the zymogen prothrombin into the functional enzyme thrombin. Although the activity of Australian elapid prothrombin-activators has been heavily investigated with ...
Nicholas J. Youngman +2 more
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Diplodactylus tessellatus Gunther, 1875 (Squamata: Diplodactylidae), Parasuta dwyeri Greer, 2006 and Suta suta Peters, 1863 (Squamata: Elapidae): distribution extension in the Murray catchment of New South Wales, South-eastern Australia [PDF]
We present new records of the Diplodactylid lizard Diplodactylus tessellatus and Elapid snakes Parasuta dwyeri and Suta suta for the Murray Catchment Management Area of New South Wales, south-eastern Australia.
Damian Michael, David Lindenmayer
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Snake venom NAD glycohydrolases: primary structures, genomic location, and gene structure [PDF]
NAD glycohydrolase (EC 3.2.2.5) (NADase) sequences have been identified in 10 elapid and crotalid venom gland transcriptomes, eight of which are complete.
Ivan Koludarov, Steven D. Aird
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Polyvalent Snake Antivenoms: Production Strategy and Their Therapeutic Benefits
Snake envenomation remains an important yet neglected medical problem in many countries, with around five million people affected, and over a hundred thousand deaths annually. Plasma-derived antivenoms are the main therapeutic agent available. Monovalent
Kavi Ratanabanangkoon
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The cytotoxicity caused by snake venoms is a serious medical problem that greatly contributes to the morbidity observed in snakebite patients. The cytotoxic components found in snake venoms belong to a variety of toxin classes and may cause cytotoxic ...
Eric Wachtel +8 more
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