Results 21 to 30 of about 2,957 (202)

Sociodemographic, geographic and temporal patterns of snakebites in Brazil: a descriptive study, 2010-2022 [PDF]

Epidemiologia e Serviços de Saúde
Objective: To analyze snakebite accidents that occurred in Brazil between 2010 and 2022, focusing on the sociodemographic characteristics of victims, snake genus involved, seasonality, geographic distribution, degree of risk and relationship with biomes.
Gisele Dias de Freitas, Thiago Salomão de Azevedo, Anderson de Oliveira, Alec Brian Lacerda, Gabriella Pereira dos Santos, Etna Leal, Flávio Santos Dourado, Hui Wen Fan, Francisco Chiaravalloti-Neto   +8 more
doaj   +5 more sources

Profiling cytotoxicity of nanofractionated elapid snake venoms in human cell lines representing different tissues [PDF]

Journal of Pharmaceutical Analysis
Elapid snakebites cause severe toxicity, predominantly neurotoxicity and general cytotoxicity. However, the specific cellular impacts of individual venom toxins remain largely underexplored.
Haifeng Xu, Mátyás A. Bittenbinder, Julien Slagboom, Nicholas R. Casewell, Paul Jennings, Jeroen Kool   +5 more
doaj   +2 more sources

Horse immunization with short-chain consensus α-neurotoxin generates antibodies against broad spectrum of elapid venomous species [PDF]

Nature Communications, 2019
Antivenoms, obtained by venom immunization, have narrow species coverage due to low immunogenicity of venom neurotoxins. Here the authors immunize horses with a designed recombinant consensus neurotoxin, and the resulting antisera protect mice from ...
Guillermo de la Rosa, Felipe Olvera, Irving G. Archundia, Bruno Lomonte, Alejandro Alagón, Gerardo Corzo   +5 more
doaj   +2 more sources

Elapid venom toxins: multiple recruitments of ancient scaffolds [PDF]

European Journal of Biochemistry, 1999
Nigroxins A and B, two myotoxic phospholipases A2 (PLA2s) from the venom of the American elapid Micrurus nigrocinctus, belong to a new PLA2 subclass. Their primary structures were established and compared with those of PLA2s that have already been studied with respect to myotoxic activity.
Alape Girón, Alberto, Persson, Bengt, Cederlund, Ella, Flores Díaz, Marietta, Gutiérrez, José María, Thelestam, Mónica, Bergman, Tomas, Jörnvall, Hans   +7 more
openaire   +5 more sources

From Venom to Vein: Factor VII Activation as a Major Pathophysiological Target for Procoagulant Australian Elapid Snake Venoms [PDF]

Toxins
Australian elapid snake venoms are uniquely procoagulant, utilizing blood clotting enzyme Factor Xa (FXa) as a toxin, which evolved as a basal trait in this clade.
Uthpala Chandrasekara, Abhinandan Chowdhury, Lorenzo Seneci, Christina N. Zdenek, Nathan Dunstan, Bryan G. Fry   +5 more
doaj   +2 more sources

Identification and Characterization of Novel Serpentoviruses in Viperid and Elapid Snakes

Viruses
Viruses in the subfamily Serpentovirinae (order Nidovirales, family Tobaniviridae) can cause significant morbidity and mortality in captive snakes, but documented infections have been limited to snakes of the Boidae, Colubridae, Homalopsidae, and ...
Steven B. Tillis, Sarah B. Chaney, Esther E. V. Crouch, Donal Boyer, Kevin Torregrosa, Avishai D. Shuter, Anibal Armendaris, April L. Childress, Denise McAloose, Jean A. Paré, Robert J. Ossiboff, Kenneth J. Conley   +11 more
doaj   +3 more sources

Hepatotoxic effect of elapid venom-a rare manifestation: Case report [PDF]

Journal of Family Medicine and Primary Care
Snake bite is a neglected tropical disease affecting millions of people across the globe. The highest burden exists in South East Asia and Sub-Saharan Africa.
Partha K. Chaudhuri, Nazifa Azam, Abha Madhur, Jyotsna Singh, Ranvijay Kumar, Anupa Prasad, Pratik Sarkar   +6 more
doaj   +2 more sources

Generalization of predator recognition: Velvet geckos display anti-predator behaviours in response to chemicals from non-dangerous elapid snakes

Current Zoology, 2010
Many prey species detect chemical cues from predators and modify their behaviours in ways that reduce their risk of predation. Theory predicts that prey should modify their anti-predator responses according to the degree of threat posed by the predator ...
Jonathan K. WEBB, Weiguo DU, David PIKE, Richard SHINE
doaj   +3 more sources

The Backbone of Regionalisation: Refining Axial Regionalisation Through 3D Morphometric Sampling Strategies on Elapid Snakes. [PDF]

J Morphol
Using 3D geometric morphometrics on every precaudal vertebra from 12 elapid snakes, this study used segmented linear regression to test regionalisation. The results show a five‐region model is best supported, including short cervical and lumbar regions and a strong heart‐aligned boundary at approximately 20% of the pre‐caudal column.
Ammresh, Camaiti M, Melville J, Evans A, Sherratt E.   +4 more
europepmc   +2 more sources

Inflammation induced by snake venoms optimizes envenomation. [PDF]

J Physiol
Abstract figure legend Schematic illustrating mechanisms underlying direct vascular absorption and subsequent movement of venom toxins into the tissues consequent to snakebite. A, snakebite into prey deposits venom toxins into the tissue interstitium, with the venom then causing acute inflammation primarily in venules.
van Helden DF, Spratt N, Dosen PJ, McFadden SA, Holdsworth J, Beard DJ, Coupland K, Jobling P, Hardy TA, Laver DR.   +9 more
europepmc   +2 more sources