Results 31 to 40 of about 1,525 (163)

Horse immunization with short-chain consensus α-neurotoxin generates antibodies against broad spectrum of elapid venomous species

Nature Communications, 2019
Antivenoms, obtained by venom immunization, have narrow species coverage due to low immunogenicity of venom neurotoxins. Here the authors immunize horses with a designed recombinant consensus neurotoxin, and the resulting antisera protect mice from ...
Guillermo de la Rosa, Felipe Olvera, Irving G. Archundia, Bruno Lomonte, Alejandro Alagón, Gerardo Corzo   +5 more
doaj   +1 more source

Platelet Desialylation Is a Novel Mechanism and Therapeutic Target in Daboia siamensis and Agkistrodon halys Envenomation-Induced Thrombocytopenia

Molecules, 2022
Venom-induced thrombocytopenia (VIT) is one of the most important hemotoxic effects of a snakebite, which is often associated with venom-induced consumptive coagulopathy (VICC).
Cheng Zhang, Zhanfeng Zhang, Enyu Liang, Yunlong Gao, Hui Li, Fangfang Xu, Weiye Chen, Ming Liu, Xianzhang Huang   +8 more
doaj   +1 more source

Transcriptomic Insights Into the Evolution of Snake Venom: Mechanisms, Diversity, and Adaptation. [PDF]

Scientifica (Cairo)
Snake venoms are evolutionarily refined biochemical arsenals composed of diverse toxins with complex functional roles in predation, defense, and competition. Over the past 2 decades, transcriptomic approaches have transformed venom research by enabling high‐resolution insights into gene expression dynamics, molecular diversity, and the evolutionary ...
Sofyantoro F, Kusuma WA, Wahyudi ST, Lumbanraja FR, Rahmawan H, Rustamaji HC, Kurniawan DW, Rastuti U, Putri WA, Wibowo WA, Priyono DS, Yudha DS, Raharjo S, Nuringtyas TR.   +13 more
europepmc   +2 more sources

Sexual dimorphism in aipysurine sea snakes (Elapidae, Hydrophiinae)

Royal Society Open Science, 2023
The transition from terrestrial to aquatic life by hydrophiine elapid snakes modified targets of natural selection and likely affected sexual selection also. Thus, the shift to marine life also might have affected sexual dimorphism.
R. Shine, T. G. Shine, G. P. Brown, V. Udyawer   +3 more
doaj   +1 more source

Pharmacokinetics of Snake Venom

Toxins, 2018
Understanding snake venom pharmacokinetics is essential for developing risk assessment strategies and determining the optimal dose and timing of antivenom required to bind all venom in snakebite patients. This review aims to explore the current knowledge
Suchaya Sanhajariya, Stephen B. Duffull, Geoffrey K. Isbister   +2 more
doaj   +1 more source

A Review and Database of Snake Venom Proteomes

Toxins, 2017
Advances in the last decade combining transcriptomics with established proteomics methods have made possible rapid identification and quantification of protein families in snake venoms.
Theo Tasoulis, Geoffrey K. Isbister
doaj   +1 more source

Occurrence and evolution of cannibal behaviour in extant snakes. [PDF]

Biol Rev Camb Philos Soc
ABSTRACT Extant snakes (Serpentes) are a highly diverse group of squamate reptiles, which have independently evolved key morphological adaptations to consume a large variety of vertebrate and invertebrate prey. While these predator–prey interactions have been widely addressed by several studies, little is known regarding the occurrence of cannibal ...
Falcão BB, São Pedro VA, Entiauspe-Neto OM.   +2 more
europepmc   +2 more sources

Snake body size frequency distributions are robust to the description of novel species

Ecosphere, 2016
The accurate interpretation of body size frequency distributions (BSFDs) has important implications for understanding large‐scale ecological and evolutionary patterns because they are shaped by ecological and evolutionary processes.
Bryan Maritz, Mimmie Kgaditse, Graham John Alexander   +2 more
doaj   +1 more source

Venoms of Rear-Fanged Snakes: New Proteins and Novel Activities

Frontiers in Ecology and Evolution, 2019
Snake venom research has focused on front-fanged venomous snakes because of the high incidence of human morbidity and mortality from envenomations and larger venom yields of these species, while venoms from rear-fanged snakes have been largely neglected.
Cassandra M. Modahl, Stephen P. Mackessy
doaj   +1 more source

No gain from pain: Lack of nociceptor activation suggests no adaptation for defence in the evolution of European viper venoms

Functional Ecology, Volume 40, Issue 10, Page 3048-3062, October 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Snake venoms show variability in composition at all taxonomic levels, both within and between species, and the selective pressures underlying this variation have long been debated.
Bálint Üveges, Samuel D. Robinson, Vanessa Schendel, Edvárd Mizsei, Ana Ćuriċ, Maria Dimaki, Vincenzo Ferri, Silviu Petrovan, Andrea V. Pozzi, Tihomir Radonjiċ, Tibor Sos, Jeffrey W. Streicher, Alexandru Strugariu, Emina Šunje, Ștefan Zamfirescu, Oleksandr Zinenko, Irina Vetter, Wolfgang Wüster   +17 more
wiley   +1 more source