Results 51 to 60 of about 1,525 (163)
Molecular Evolution and Phylogeny of Elapid Snake Venom Three-Finger Toxins [PDF]
Animal venom components are of considerable interest to researchers across a wide variety of disciplines, including molecular biology, biochemistry, medicine, and evolutionary genetics. The three-finger family of snake venom peptides is a particularly interesting and biochemically complex group of venom peptides, because they are encoded by a large ...
Fry, B.G. +6 more
openaire +5 more sources
ABSTRACT Snakebite envenomation is a major public health concern, particularly in low‐ and middle‐income regions where access to safe and effective antivenoms is limited. Traditional antivenoms, derived from immunization with crude venom, often trigger adverse reactions and lack specificity against key venom components.
Hanan Maoz, Amir Elalouf
wiley +1 more source
Elapid snake venom is a highly valuable, but till now mainly unexplored, source of pharmacologically important peptides. We analyzed the peptide fractions with molecular masses up to 10 kDa of two elapid snake venoms—that of the African cobra, N.
Aisha Munawar +10 more
doaj +1 more source
Full-Length Venom Protein cDNA Sequences from Venom-Derived mRNA: Exploring Compositional Variation and Adaptive Multigene Evolution. [PDF]
Envenomation of humans by snakes is a complex and continuously evolving medical emergency, and treatment is made that much more difficult by the diverse biochemical composition of many venoms.
Cassandra M Modahl, Stephen P Mackessy
doaj +1 more source
Some Australian elapids possess potently procoagulant coagulotoxic venoms which activate the zymogen prothrombin into the functional enzyme thrombin. Although the activity of Australian elapid prothrombin-activators has been heavily investigated with ...
Nicholas J. Youngman +2 more
doaj +1 more source
A bicycle dragon (Ctenophorus cristatus) consumes a Jan's banded snake (Simoselaps bertholdi) near the Gawler Ranges National Park in South Australia. This observation is unusual because vertebrate prey make up a vanishingly small portion of the Ctenophorus dragon diet.
Daniel Hoops
wiley +1 more source
ABSTRACT Snakes are experiencing global population decline due to habitat loss, environmental degradation, pollution and climate change, yet effective conservation is often hindered by their cryptic behaviour and low detectability. In this study, we conducted targeted surveys and estimated detection probabilities for the endangered grey snake ...
Damian R. Michael +3 more
wiley +1 more source
Venom‐derived peptide diversity from Naja mandalayensis reveals bioactive subfractions capable of modulating neuronal oxidative stress responses. Integration of RP‐HPLC fractionation and proteomics identifies toxin families associated with improved mitochondrial function and cellular integrity in mHippoE‐18 cells, supporting venoms as a platform for ...
Brenda Rufino da Silva +3 more
wiley +1 more source
Snake Venom Protease Detection and Inhibition in Serum
A fluorescence assay enables sensitive detection of the activities of snake venom metalloproteases (SVMP) and serine proteases (SVSP) from viper venoms in buffer and serum. In combination with effective low‐molecular‐weight inhibitors such as ilomastat and nafamostat, this approach offers new prospects for the rapid diagnosis and adjunctive therapy of ...
Mareike Riedel, Christian Kersten
wiley +1 more source
Australian elapid snake envenomation in cats: Clinical priorities and approach
Practical relevance: No fewer than 140 species of terrestrial snakes reside in Australia, 92 of which possess venom glands. With the exception of the brown tree snake, the venom-producing snakes belong to the family Elapidae. The venom of a number of elapid species is more toxic than that of the Indian cobra and
Trudi J, Mcalees, Linda A, Abraham
openaire +2 more sources

