Results 71 to 80 of about 1,525 (163)

Phospholipase A2 (PLA₂) as an Early Indicator of Envenomation in Australian Elapid Snakebites (ASP-27)

Biomedicines, 2020
Early diagnosis of snake envenomation is essential, especially neurotoxicity and myotoxicity. We investigated the diagnostic value of serum phospholipase (PLA2) in Australian snakebites.
Geoffrey K. Isbister, Nandita Mirajkar, Kellie Fakes, Simon G. A. Brown, Punnam Chander Veerati   +4 more
doaj   +1 more source

Complete mitochondrial genome of the Ijima's Sea Snake (Emydocephalus ijimae) (Squamata, Elapidae)

Mitochondrial DNA. Part B. Resources, 2019
In this study, we provide the first report of the complete mitochondrial genome of Emydocephalus ijimae. The mitogenome length is 18,259 bp and includes 13 protein-coding genes, two rRNA genes, 22 tRNA genes, and three non-coding regions.
Chang-Ho Yi, Jaejin Park, Takahide Sasai, Hye Seon Kim, Jong-Gwan Kim, Min-Seop Kim, In-Young Cho, Il-Hun Kim   +7 more
doaj   +1 more source

Why is Skeletal Muscle Regeneration Impaired after Myonecrosis Induced by Viperid Snake Venoms?

Toxins, 2018
Skeletal muscle regeneration after myonecrosis involves the activation, proliferation and fusion of myogenic cells, and a coordinated inflammatory response encompassing phagocytosis of necrotic cell debris, and the concerted synthesis of cytokines and ...
José María Gutiérrez, Teresa Escalante, Rosario Hernández, Stefano Gastaldello, Patricia Saravia-Otten, Alexandra Rucavado   +5 more
doaj   +1 more source

A novel in vitro potency assay of antisera against Thai Naja kaouthia based on nicotinic acetylcholine receptor binding

Scientific Reports, 2017
Snake envenomation is an important medical problem. One of the hurdles in antivenom development is the in vivo assay of antivenom potency which is expensive, gives variable results and kills many animals.
Kavi Ratanabanangkoon, Pavinee Simsiriwong, Kritsada Pruksaphon, Kae Yi Tan, Sukanya Eursakun, Choo Hock Tan, Bunkuea Chantrathonkul, Wongsakorn Wongwadhunyoo, Sirida Youngchim, Nget Hong Tan   +9 more
doaj   +1 more source

Generation of Multivalent Nanobody-Based Proteins with Improved Neutralization of Long α-Neurotoxins from Elapid Snakes. [PDF]

Bioconjug Chem, 2022
Wade J, Rimbault C, Ali H, Ledsgaard L, Rivera-de-Torre E, Abou Hachem M, Boddum K, Mirza N, Bohn MF, Sakya SA, Ruso-Julve F, Andersen JT, Laustsen AH.   +12 more
europepmc   +1 more source

A Documented Case of Ichthyophagy in the Malayan Krait (Bungarus candidus) and Its Implications for Toxinology

Diversity
Snakebite is a neglected tropical disease, and the high potency of snake venoms has been evolutionary refined for trophic interactions. Hence, understanding the feeding ecology of snakes is a major element needed to meaningfully interpret toxinological ...
Tim Lüddecke
doaj   +1 more source

From Venom to Vein: Factor VII Activation as a Major Pathophysiological Target for Procoagulant Australian Elapid Snake Venoms

Toxins
Australian elapid snake venoms are uniquely procoagulant, utilizing blood clotting enzyme Factor Xa (FXa) as a toxin, which evolved as a basal trait in this clade.
Uthpala Chandrasekara, Abhinandan Chowdhury, Lorenzo Seneci, Christina N. Zdenek, Nathan Dunstan, Bryan G. Fry   +5 more
doaj   +1 more source

A cryptic elapid snake persists in the wake of catastrophic wildfires

Oryx
AbstractThe increased severity and frequency of bushfires accompanying human-induced global warming have dire implications for biodiversity conservation. Here we investigate the response of a cryptic, cool-climate elapid, the mustard-bellied snake Drysdalia rhodogaster, to the extensive Black Summer fires of 2019/2020 in south-eastern Australia.
Mitchell J. Hodgson, Alexandra K. Ross, Yingyod Lapwong, Santiago Cuartas, Bridget Roberts, Owen Price, Jonathan Webb, Nicola Sentinella, Joshua Lee, Shawn W. Laffan, Hugh M. Burley, Finlay McIntosh, Mike Letnic   +12 more
openaire   +2 more sources

A polygeneric immunogen composed of 22 venoms from sub-Saharan African snakes to expand the neutralization scope of the EchiTAb-plus-ICP antivenom

Toxicon: X
Recent research suggests that a polygeneric immunogen made from the venoms of the most medically important viperid and elapid snakes in sub-Saharan Africa could elicit a broader antibody response in horses compared to the current EchiTAb-plus-ICP ...
Andrés Sánchez, Gina Durán, Maykel Cerdas, Jairo Gutiérrez, Álvaro Segura, María Herrera, Mariángela Vargas, Adriana Sánchez, Paola Sánchez, Gabriela Solano, Mauren Villalta, Edwin Moscoso, Deibid Umaña, Mauricio Arguedas, Aarón Gómez, José María Gutiérrez, Guillermo León   +16 more
doaj   +1 more source

Unveiling Novel Kunitz- and Waprin-Type Toxins in the Micrurus mipartitus Coral Snake Venom Gland: An In Silico Transcriptome Analysis

Toxins
Kunitz-type peptide expression has been described in the venom of snakes of the Viperidae, Elapidae and Colubridae families. This work aimed to identify these peptides in the venom gland transcriptome of the coral snake Micrurus mipartitus ...
Mónica Saldarriaga-Córdoba, Claudia Clavero-León, Paola Rey-Suarez, Vitelbina Nuñez-Rangel, Ruben Avendaño-Herrera, Stefany Solano-González, Juan F. Alzate   +6 more
doaj   +1 more source