Results 171 to 180 of about 2,588 (206)
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Structure–function properties of venom components from Australian elapids
Toxicon, 1999A comprehensive review of venom components isolated thus far from Australian elapids. Illustrated is that a tremendous structural homology exists among the components but this homology is not representative of the functional diversity. Further, the review illuminates the overlooked species and areas of research.
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Cloning and characterisation of novel cystatins from elapid snake venom glands
Biochimie, 2011Snake venoms contain a complex mixture of polypeptides that modulate prey homeostatic mechanisms through highly specific and targeted interactions. In this study we have identified and characterised cystatin-like cysteine-protease inhibitors from elapid snake venoms for the first time.
Richards, Renee +6 more
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Immunological and histochemical identity of esterases and other antigens in elapid venoms
Toxicon, 1972Abstract Antibodies were prepared by hyperimmunizing rabbits with Naja naja, Bungarus fasciatus, Agkistrodon piscivorus and Apis mellifera (honeybee) venoms. By using immuno-electrophoresis, Ouchterlony technique and histochemical reactions, the identity of certain antigenic components and esterases in several elapid venoms has been demonstrated.
D, Munjal, W B, Elliott
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The preparation of 3-nitrotyrosyl derivatives of three elapid venom cardiotoxins
Biochimica et Biophysica Acta (BBA) - Protein Structure, 1980Nitration studies using tetranitromethane were conducted on the tyrosine residues of cardiotoxins, naja melanoleuca VII1, Naja haje annulifera VII1 and Hemachatus haemachates toxin 12B. Various partially and fully nitrated derivatives were formed. Analysis of the products of nitrating naja melanoleuca VII1 showed that the average relative reactivities ...
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A comparative study of the homology of certain enzymes in elapid venoms
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1971Abstract 1. 1. Similar electrophoretic mobilities for esterases with identical substrate specificities have been shown for the venoms of several closely related elapidae. 2. 2. Two lactate dehydrogenase isozymes were shown for most Naja venoms with the slower migrating band (at alkaline pH's) showing constant mobility for all Naja species
R L, McLean, E J, Massaro, W B, Elliott
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Neutralization of tiger snake (Notechis scutatus) venom by serum from other Australian elapids
Toxicon, 1993Sera from four Australian elapids and one boidid (python) were tested for their ability to protect neonatal mice against the toxic action of tiger snake (Notechis scutatus) venom. Of the five serum samples tested, only serum from Pseudechis australis and Pseudechis porphyriacus were capable of neutralizing the tiger snake venom.
M J, Thurn, K W, Broady, P J, Mirtschin
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Three-finger toxins, a deadly weapon of elapid venom – Milestones of discovery
Toxicon, 2013Three-finger toxins (TFTs) are the main venom components of snakes from Elapidae family. Amino acid sequences of more than five hundreds TFTs are determined; these toxins form one of the largest protein families present in snake venoms. The first TFT α-bungarotoxin was isolated almost half a century ago and so far it remains a valuable tool in the ...
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The selective S-alkylation of a methionine residue in an elapid venom cardiotoxin
International Journal of Biochemistry, 19871. The reaction of cardiotoxin with iodoacetamide or iodomethane at pH 3.0 afforded the corresponding methionine sulphonium derivatives. The major products were S-alkylated at Met-26 whilst the minor products were S-alkylated at both Met-24 and -26. 2. Reaction with iodoacetamide under denaturing conditions led to a reversal of the relative abundances ...
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Histology, histochemistry, and emptying mechanism of the venom glands of some elapid snakes
Journal of Morphology, 1967AbstractThe venom glands of several species of elapid snakes are described. The main venom gland consists of many tubules which usually contain large amounts of secretion product. The accessory gland surrounds the entire venom duct and is usually composed of uniform mucous epithelium.
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Neurotoxic, cytotoxic and cardiovascular effects of some Australasian elapid venoms
2017A range of toxic components found in Australasian elapid venoms have been postulated to account for the clinical outcomes of envenoming. Depending on the species of snake, these outcomes may include neurotoxicity with flaccid paralysis, coagulopathy with spontaneous systemic hemorrhage, sudden cardiovascular collapse, and myotoxicity with skeletal ...
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