Results 161 to 170 of about 1,869 (190)

Are neurotoxins from elapid venoms glycoproteins?

Toxicon, 1971
S Y, Lin, C Y, Lee
exaly   +3 more sources

Identification and discrimination of snake venoms from Egyptian elapids

Toxicon, 2013
The avidity to the corresponding antigens is often higher than to the cross-reactive antigens. This was demonstrated with the highly cross-reactive elapid Egyptian snake venoms Naja haje (Nh), Naja nigricollis (Nn) and Walterinnesia aegyptia (Wa), and used for the differentiation among the three species in a simple ELISA-based assay.
Nihal M, Ibrahim, Ebtsam M, El-Kady, Rania A, Katamesh, Ibrahim H, El-Borei, Ahmed F, Wahby   +4 more
openaire   +2 more sources

Conformational Properties of the Neurotoxins and Cytotoxins Isolated from Elapid Snake Venoms

Critical Reviews in Biochemistry, 1983
The review will critically assess the information available on the conformation of homologous neurotoxins and cytotoxins isolated from Elapid snakes. Particular attention will be given to the dynamics of the molecules in solution because there is the possibility that defined intramolecular rearrangements are involved at the sites of action.
Mark J Dufton, R C Hider
exaly   +3 more sources

Venom ophthalmia caused by venoms of spitting elapid and other snakes: Report of ten cases with review of epidemiology, clinical features, pathophysiology and management

Toxicon, 2010
Venom ophthalmia caused by venoms of spitting elapid and other snakes: report of ten cases with review of epidemiology, clinical features, pathophysiology and management. Chu, ER, Weinstein, SA, White, J and Warrell, DA. Toxicon XX:xxx-xxx.
Scott A Weinstein, Julian White, David A Warrell   +2 more
exaly   +2 more sources

Cloning and characterisation of natriuretic peptides from the venom glands of Australian elapids

Biochimie, 2006
The venom from Australian elapid snakes contains a complex mixture of polypeptide toxins that adversely affect multiple homeostatic systems within their prey in a highly specific and targeted manner. Included in these toxin families are the recently described venom natriuretic peptides, which display similar structure and vasoactive functions to ...
St Pierre, Liam, Flight, Simone M., Masci, Paul P., Hanchard, Kim J., Lewis, Richard J., Alewood, Paul F., De Jersey, John, Lavin, Martin F.   +7 more
openaire   +5 more sources

Structure–function properties of venom components from Australian elapids

Toxicon, 1999
A comprehensive review of venom components isolated thus far from Australian elapids. Illustrated is that a tremendous structural homology exists among the components but this homology is not representative of the functional diversity. Further, the review illuminates the overlooked species and areas of research.
openaire   +4 more sources

The preparation of 3-nitrotyrosyl derivatives of three elapid venom cardiotoxins

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1980
Nitration studies using tetranitromethane were conducted on the tyrosine residues of cardiotoxins, naja melanoleuca VII1, Naja haje annulifera VII1 and Hemachatus haemachates toxin 12B. Various partially and fully nitrated derivatives were formed. Analysis of the products of nitrating naja melanoleuca VII1 showed that the average relative reactivities ...
openaire   +2 more sources

Anticoagulant activity in Australasian elapid snake venoms and neutralisation with antivenom and varespladib

Toxicon
The venoms of Australasian elapid snakes are known to possess coagulant activity, including some with strong procoagulant activity and others with anticoagulant activity, although the latter are less well known. This study investigates the anticoagulant activity of Australasian elapid snake venoms, and whether this activity is neutralised by commercial
Kate Murphy, Theo Tasoulis, Nathan Dunstan   +2 more
exaly   +3 more sources

The selective S-alkylation of a methionine residue in an elapid venom cardiotoxin

International Journal of Biochemistry, 1987
1. The reaction of cardiotoxin with iodoacetamide or iodomethane at pH 3.0 afforded the corresponding methionine sulphonium derivatives. The major products were S-alkylated at Met-26 whilst the minor products were S-alkylated at both Met-24 and -26. 2. Reaction with iodoacetamide under denaturing conditions led to a reversal of the relative abundances ...
openaire   +2 more sources

Three-finger toxins, a deadly weapon of elapid venom – Milestones of discovery

Toxicon, 2013
Three-finger toxins (TFTs) are the main venom components of snakes from Elapidae family. Amino acid sequences of more than five hundreds TFTs are determined; these toxins form one of the largest protein families present in snake venoms. The first TFT α-bungarotoxin was isolated almost half a century ago and so far it remains a valuable tool in the ...
openaire   +2 more sources